JP2004525888A5 - - Google Patents
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- Publication number
- JP2004525888A5 JP2004525888A5 JP2002559370A JP2002559370A JP2004525888A5 JP 2004525888 A5 JP2004525888 A5 JP 2004525888A5 JP 2002559370 A JP2002559370 A JP 2002559370A JP 2002559370 A JP2002559370 A JP 2002559370A JP 2004525888 A5 JP2004525888 A5 JP 2004525888A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- methoxy
- phenylsulfonyl
- integer
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *OC([C@](CCC1)N1C([C@@](CC1CCCCC1)NCC(NCC*O)=O)=O)=O Chemical compound *OC([C@](CCC1)N1C([C@@](CC1CCCCC1)NCC(NCC*O)=O)=O)=O 0.000 description 3
- LDDXTZJQVINROX-UHFFFAOYSA-N CNCc(cc1)ccc1C(N)=N Chemical compound CNCc(cc1)ccc1C(N)=N LDDXTZJQVINROX-UHFFFAOYSA-N 0.000 description 2
- MSPORBDQRNSRAM-UHFFFAOYSA-N CNCC(CC1)CCN1C(N)=N Chemical compound CNCC(CC1)CCN1C(N)=N MSPORBDQRNSRAM-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10102878A DE10102878A1 (de) | 2001-01-23 | 2001-01-23 | Oligo- oder Polyalkylengekoppelte Thrombininhibitoren |
| PCT/EP2002/000652 WO2002059065A2 (de) | 2001-01-23 | 2002-01-23 | Oligo- oder polyalkylenglycolgekoppelte thrombininhibitoren |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004525888A JP2004525888A (ja) | 2004-08-26 |
| JP2004525888A5 true JP2004525888A5 (https=) | 2008-04-10 |
| JP4461217B2 JP4461217B2 (ja) | 2010-05-12 |
Family
ID=7671444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002559370A Expired - Fee Related JP4461217B2 (ja) | 2001-01-23 | 2002-01-23 | オリゴまたはポリアルキレングリコール結合トロンビン阻害剤 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7407982B2 (https=) |
| EP (1) | EP1355674B1 (https=) |
| JP (1) | JP4461217B2 (https=) |
| AT (1) | ATE485838T1 (https=) |
| CA (1) | CA2431487C (https=) |
| DE (2) | DE10102878A1 (https=) |
| WO (1) | WO2002059065A2 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10162521A1 (de) * | 2001-12-19 | 2003-07-17 | Goetz Nowak | Verwendung von molekulargewichtserweiterten Substanzen in der Tumortherapie |
| US7838560B2 (en) * | 2002-03-11 | 2010-11-23 | The Medicines Company (Leipzig) Gmbh | Urokinase inhibitors, production and use thereof |
| DE10301300B4 (de) * | 2003-01-15 | 2009-07-16 | Curacyte Chemistry Gmbh | Verwendung von acylierten 4-Amidino- und 4-Guanidinobenzylaminen zur Inhibierung von Plasmakallikrein |
| DE10342108A1 (de) * | 2003-09-11 | 2005-04-14 | Curacyte Chemistry Gmbh | Basisch-substituierte Benzylaminanaloga als Inhibitoren des Gerinnungsfaktors Xa, ihre Herstellung und Verwendung |
| DK1737889T3 (da) | 2004-10-19 | 2011-01-03 | Lonza Ag | Fremgangsmåde til fastfase-peptidsyntese |
| DE102005044319A1 (de) * | 2005-09-16 | 2007-03-22 | Curacyte Chemistry Gmbh | 2-(Aminomethyl)-5-Chlor-Benzylamid-Derivate und ihre Verwendung als Hemmstoffe des Gerinnungsfaktors Xa |
| DE102006048300A1 (de) | 2006-01-26 | 2007-08-02 | Hellstern, Peter, Prof. Dr.med. | Inhibitoren des Blutgerinnungsfaktors Xa zur Verwendung als Antikoagulans |
| JPWO2008032758A1 (ja) * | 2006-09-15 | 2010-01-28 | 東レ株式会社 | 基材およびその製造方法 |
| WO2008032400A1 (fr) * | 2006-09-15 | 2008-03-20 | Toray Industries, Inc. | Procédé pour la production d'un substrat modifié |
| DE102006050672A1 (de) | 2006-10-24 | 2008-04-30 | Curacyte Discovery Gmbh | Hemmstoffe des Plasmins und des Plasmakallikreins |
| DE102007033787A1 (de) | 2007-07-09 | 2009-01-15 | Aesculap Ag | Gefäßprothese mit reduzierter Thrombogenität |
| WO2010033226A1 (en) * | 2008-09-17 | 2010-03-25 | Nektar Therapeutics | Oligomer-protease inhibitor conjugates |
| US8835710B2 (en) * | 2009-03-24 | 2014-09-16 | Mead Johnson Nutrition Company | Animal model for infant pathologies |
| TWI476020B (zh) | 2009-12-24 | 2015-03-11 | Toray Industries | 具有抗血液凝固作用之親水性高分子化合物、包含其之醫療器材或醫療材料之表面處理劑、以及經其處理之醫療器材或醫療材料 |
| ES2703176T3 (es) | 2010-03-11 | 2019-03-07 | Univ New York | Compuestos amido como moduladores de RORgammat y usos de los mismos |
| EP2655399B1 (en) | 2010-12-21 | 2017-09-27 | The Medicines Company (Leipzig) GmbH | Trypsin-like serine protease inhibitors, their preparation and use as selective inhibitors of the clotting factors iia and xa |
| TW201309354A (zh) | 2011-06-23 | 2013-03-01 | Toray Industries | 醫療材料 |
| TW201311774A (zh) * | 2011-06-23 | 2013-03-16 | Toray Industries | 具有抗血液凝固作用的疏水性高分子化合物 |
| JPWO2012176841A1 (ja) * | 2011-06-24 | 2015-02-23 | 寛治 井上 | 遊離血栓捕獲器具 |
| EP2985041B1 (en) * | 2013-04-12 | 2017-07-19 | Toray Industries, Inc. | Antithrombotic artificial blood vessel |
| EP3075400A4 (en) | 2013-11-28 | 2017-07-19 | Toray Industries, Inc. | Anti-thrombotic material |
| CA2935808C (en) * | 2014-02-12 | 2018-08-21 | Toray Industries, Inc. | Artificial blood vessel |
| JP6863295B2 (ja) | 2016-10-07 | 2021-04-21 | 東レ株式会社 | 筒状織物 |
| CA3058121A1 (en) | 2017-03-31 | 2018-10-04 | Toray Industries, Inc. | Cylindrical structure |
| CN117497842B (zh) * | 2023-12-27 | 2024-03-12 | 江苏蓝固新能源科技有限公司 | 一种聚合物电解质和制备方法及其在二次电池中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991008229A1 (de) | 1989-12-01 | 1991-06-13 | Basf Aktiengesellschaft | Hirudinpolyalkylenglykolkonjugate |
| US5583146A (en) | 1992-12-02 | 1996-12-10 | Bristol-Myers Squibb Company | Heterocyclic thrombin inhibitors |
| DE4342154A1 (de) * | 1993-12-10 | 1995-06-14 | Behringwerke Ag | Amidinophenylalaninderivate, Verfahren zu deren Herstellung, deren Verwendung und diese enthaltende Mittel als Antikoagulantien |
| US5914319A (en) * | 1995-02-27 | 1999-06-22 | Eli Lilly And Company | Antithrombotic agents |
| US5798377A (en) * | 1996-10-21 | 1998-08-25 | Merck & Co., Inc. | Thrombin inhibitors |
| DE69800640T2 (de) * | 1997-01-29 | 2001-07-05 | Polymasc Pharmaceuticals Plc, London | Pegylationsverfahren |
-
2001
- 2001-01-23 DE DE10102878A patent/DE10102878A1/de not_active Ceased
-
2002
- 2002-01-23 CA CA2431487A patent/CA2431487C/en not_active Expired - Fee Related
- 2002-01-23 JP JP2002559370A patent/JP4461217B2/ja not_active Expired - Fee Related
- 2002-01-23 AT AT02708308T patent/ATE485838T1/de active
- 2002-01-23 WO PCT/EP2002/000652 patent/WO2002059065A2/de not_active Ceased
- 2002-01-23 DE DE50214734T patent/DE50214734D1/de not_active Expired - Lifetime
- 2002-01-23 US US10/344,722 patent/US7407982B2/en not_active Expired - Fee Related
- 2002-01-23 EP EP02708308A patent/EP1355674B1/de not_active Expired - Lifetime