JP2004525623A - ディファレンシャルに発現する同義遺伝子のコンカテマー - Google Patents
ディファレンシャルに発現する同義遺伝子のコンカテマー Download PDFInfo
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- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| DKPA200100127 | 2001-01-25 | ||
| US30102201P | 2001-06-27 | 2001-06-27 | |
| PCT/DK2002/000055 WO2002059296A2 (en) | 2001-01-25 | 2002-01-25 | Concatemers of differentially expressed multiple genes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| JP2009287858A Division JP5001346B2 (ja) | 2001-01-25 | 2009-12-18 | ディファレンシャルに発現する同義遺伝子のコンカテマー |
Publications (2)
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| JP2004525623A true JP2004525623A (ja) | 2004-08-26 |
| JP2004525623A5 JP2004525623A5 (https=) | 2005-12-22 |
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| JP2002559583A Withdrawn JP2004525623A (ja) | 2001-01-25 | 2002-01-25 | ディファレンシャルに発現する同義遺伝子のコンカテマー |
| JP2009287858A Expired - Fee Related JP5001346B2 (ja) | 2001-01-25 | 2009-12-18 | ディファレンシャルに発現する同義遺伝子のコンカテマー |
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| JP2009287858A Expired - Fee Related JP5001346B2 (ja) | 2001-01-25 | 2009-12-18 | ディファレンシャルに発現する同義遺伝子のコンカテマー |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1360308B1 (https=) |
| JP (2) | JP2004525623A (https=) |
| AT (1) | ATE375394T1 (https=) |
| AU (1) | AU2002227882B2 (https=) |
| CA (1) | CA2474161C (https=) |
| DE (1) | DE60222857T2 (https=) |
| NZ (1) | NZ527208A (https=) |
| WO (1) | WO2002059296A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220243243A1 (en) * | 2019-06-13 | 2022-08-04 | Global Life Sciences Solutions Usa Llc | Expression of products from nucleic acid concatemers |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7235716B2 (en) | 1997-06-03 | 2007-06-26 | Chromatin, Inc. | Plant centromere compositions |
| US7193128B2 (en) | 1997-06-03 | 2007-03-20 | Chromatin, Inc. | Methods for generating or increasing revenues from crops |
| US7119250B2 (en) | 1997-06-03 | 2006-10-10 | The University Of Chicago | Plant centromere compositions |
| US7227057B2 (en) | 1997-06-03 | 2007-06-05 | Chromatin, Inc. | Plant centromere compositions |
| US8008459B2 (en) | 2001-01-25 | 2011-08-30 | Evolva Sa | Concatemers of differentially expressed multiple genes |
| DE60239386D1 (de) | 2001-01-25 | 2011-04-21 | Evolva Ltd | Zellbibliothek |
| AU2003247270A1 (en) * | 2002-08-01 | 2004-03-03 | Evolva Ltd | Methods of mixing large numbers of heterologous genes |
| NZ554824A (en) | 2004-10-22 | 2010-10-29 | Revivicor Inc | Porcines that lack endogenous antibody chains and express exogenous immunoglobulins |
| EP2348827B1 (en) | 2008-10-27 | 2015-07-01 | Revivicor, Inc. | Immunocompromised ungulates |
| EP2456894A4 (en) | 2009-07-23 | 2013-09-25 | Chromatin Inc | CENTROMER SEQUENCES AND SORGHUM MINI-CHROMOSOMES |
| WO2011146833A1 (en) | 2010-05-20 | 2011-11-24 | Evolva Inc. | Method of producing isoprenoid compounds in yeast |
| JP6261500B2 (ja) | 2011-07-22 | 2018-01-17 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ヌクレアーゼ切断特異性の評価および改善 |
| JP6295512B2 (ja) * | 2012-03-15 | 2018-03-20 | 株式会社豊田中央研究所 | 酵母における外来遺伝子の発現産物の生産方法、酵母における発現調節剤及びその利用 |
| US20150044192A1 (en) | 2013-08-09 | 2015-02-12 | President And Fellows Of Harvard College | Methods for identifying a target site of a cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9388430B2 (en) | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
| US9340799B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | MRNA-sensing switchable gRNAs |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| US20150165054A1 (en) | 2013-12-12 | 2015-06-18 | President And Fellows Of Harvard College | Methods for correcting caspase-9 point mutations |
| WO2016022363A2 (en) | 2014-07-30 | 2016-02-11 | President And Fellows Of Harvard College | Cas9 proteins including ligand-dependent inteins |
| CN106591370A (zh) * | 2015-10-19 | 2017-04-26 | 南京华贞生物医药科技有限公司 | 一种治疗自身免疫性相关疾病以及糖尿病的病毒载体及其构建方法和应用 |
| JP7109784B2 (ja) | 2015-10-23 | 2022-08-01 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 遺伝子編集のための進化したＣａｓ９蛋白質 |
| KR102547316B1 (ko) | 2016-08-03 | 2023-06-23 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 아데노신 핵염기 편집제 및 그의 용도 |
| US11661590B2 (en) | 2016-08-09 | 2023-05-30 | President And Fellows Of Harvard College | Programmable CAS9-recombinase fusion proteins and uses thereof |
| US11542509B2 (en) | 2016-08-24 | 2023-01-03 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
| EP3526320A1 (en) | 2016-10-14 | 2019-08-21 | President and Fellows of Harvard College | Aav delivery of nucleobase editors |
| WO2018119359A1 (en) | 2016-12-23 | 2018-06-28 | President And Fellows Of Harvard College | Editing of ccr5 receptor gene to protect against hiv infection |
| EP3592853A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Suppression of pain by gene editing |
| JP2020510038A (ja) | 2017-03-09 | 2020-04-02 | プレジデント アンド フェローズ オブ ハーバード カレッジ | がんワクチン |
| JP2020510439A (ja) | 2017-03-10 | 2020-04-09 | プレジデント アンド フェローズ オブ ハーバード カレッジ | シトシンからグアニンへの塩基編集因子 |
| CA3057192A1 (en) | 2017-03-23 | 2018-09-27 | President And Fellows Of Harvard College | Nucleobase editors comprising nucleic acid programmable dna binding proteins |
| WO2018209320A1 (en) | 2017-05-12 | 2018-11-15 | President And Fellows Of Harvard College | Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation |
| WO2019023680A1 (en) | 2017-07-28 | 2019-01-31 | President And Fellows Of Harvard College | METHODS AND COMPOSITIONS FOR EVOLUTION OF BASIC EDITORS USING PHAGE-ASSISTED CONTINUOUS EVOLUTION (PACE) |
| EP3676376B1 (en) | 2017-08-30 | 2025-01-15 | President and Fellows of Harvard College | High efficiency base editors comprising gam |
| KR20250107288A (ko) | 2017-10-16 | 2025-07-11 | 더 브로드 인스티튜트, 인코퍼레이티드 | 아데노신 염기 편집제의 용도 |
| WO2019118949A1 (en) | 2017-12-15 | 2019-06-20 | The Broad Institute, Inc. | Systems and methods for predicting repair outcomes in genetic engineering |
| EP3797160A1 (en) | 2018-05-23 | 2021-03-31 | The Broad Institute Inc. | Base editors and uses thereof |
| US12522807B2 (en) | 2018-07-09 | 2026-01-13 | The Broad Institute, Inc. | RNA programmable epigenetic RNA modifiers and uses thereof |
| WO2020092453A1 (en) | 2018-10-29 | 2020-05-07 | The Broad Institute, Inc. | Nucleobase editors comprising geocas9 and uses thereof |
| US12351837B2 (en) | 2019-01-23 | 2025-07-08 | The Broad Institute, Inc. | Supernegatively charged proteins and uses thereof |
| JP7657726B2 (ja) | 2019-03-19 | 2025-04-07 | ザ ブロード インスティテュート，インコーポレーテッド | 編集ヌクレオチド配列を編集するための方法および組成物 |
| US12473543B2 (en) | 2019-04-17 | 2025-11-18 | The Broad Institute, Inc. | Adenine base editors with reduced off-target effects |
| US12435330B2 (en) | 2019-10-10 | 2025-10-07 | The Broad Institute, Inc. | Methods and compositions for prime editing RNA |
| DE112021002672T5 (de) | 2020-05-08 | 2023-04-13 | President And Fellows Of Harvard College | Vefahren und zusammensetzungen zum gleichzeitigen editieren beider stränge einer doppelsträngigen nukleotid-zielsequenz |
| CN116312618B (zh) * | 2023-03-27 | 2025-09-16 | 中科南京智能技术研究院 | 一种说话人识别方法及系统 |
Family Cites Families (2)
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| US5316922A (en) * | 1992-04-15 | 1994-05-31 | The United States Of America As Represented By Department Of Health And Human Services | Method for indentifying and expressing proteins that recognize and adhere to specific probes |
| US6242211B1 (en) * | 1996-04-24 | 2001-06-05 | Terragen Discovery, Inc. | Methods for generating and screening novel metabolic pathways |
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2002
- 2002-01-25 EP EP02709978A patent/EP1360308B1/en not_active Expired - Lifetime
- 2002-01-25 CA CA2474161A patent/CA2474161C/en not_active Expired - Fee Related
- 2002-01-25 DE DE60222857T patent/DE60222857T2/de not_active Expired - Lifetime
- 2002-01-25 AT AT02709978T patent/ATE375394T1/de active
- 2002-01-25 NZ NZ527208A patent/NZ527208A/en not_active IP Right Cessation
- 2002-01-25 WO PCT/DK2002/000055 patent/WO2002059296A2/en not_active Ceased
- 2002-01-25 AU AU2002227882A patent/AU2002227882B2/en not_active Ceased
- 2002-01-25 JP JP2002559583A patent/JP2004525623A/ja not_active Withdrawn
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2009
- 2009-12-18 JP JP2009287858A patent/JP5001346B2/ja not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220243243A1 (en) * | 2019-06-13 | 2022-08-04 | Global Life Sciences Solutions Usa Llc | Expression of products from nucleic acid concatemers |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1360308B1 (en) | 2007-10-10 |
| EP1360308A2 (en) | 2003-11-12 |
| WO2002059296A8 (en) | 2004-04-15 |
| AU2002227882C9 (en) | 2002-08-06 |
| NZ527208A (en) | 2005-05-27 |
| WO2002059296A3 (en) | 2003-05-01 |
| WO2002059296A2 (en) | 2002-08-01 |
| CA2474161C (en) | 2012-03-27 |
| ATE375394T1 (de) | 2007-10-15 |
| DE60222857T2 (de) | 2008-07-17 |
| AU2002227882B2 (en) | 2007-06-28 |
| DE60222857D1 (de) | 2007-11-22 |
| JP2010057519A (ja) | 2010-03-18 |
| AU2002227882C1 (en) | 2002-08-06 |
| CA2474161A1 (en) | 2002-08-01 |
| JP5001346B2 (ja) | 2012-08-15 |
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