JP2004523267A5 - - Google Patents
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- Publication number
- JP2004523267A5 JP2004523267A5 JP2002552605A JP2002552605A JP2004523267A5 JP 2004523267 A5 JP2004523267 A5 JP 2004523267A5 JP 2002552605 A JP2002552605 A JP 2002552605A JP 2002552605 A JP2002552605 A JP 2002552605A JP 2004523267 A5 JP2004523267 A5 JP 2004523267A5
- Authority
- JP
- Japan
- Prior art keywords
- chlorhexidine
- medical article
- percent
- concentration
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 claims 82
- 229960003260 chlorhexidine Drugs 0.000 claims 57
- 239000012458 free base Substances 0.000 claims 37
- 230000000845 anti-microbial effect Effects 0.000 claims 36
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 33
- 239000002904 solvent Substances 0.000 claims 26
- 238000000034 method Methods 0.000 claims 22
- 239000000203 mixture Substances 0.000 claims 21
- 150000003839 salts Chemical class 0.000 claims 20
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 16
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 claims 16
- 230000000844 anti-bacterial effect Effects 0.000 claims 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 10
- WDRFFJWBUDTUCA-UHFFFAOYSA-N chlorhexidine acetate Chemical group CC(O)=O.CC(O)=O.C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 WDRFFJWBUDTUCA-UHFFFAOYSA-N 0.000 claims 8
- 229960001884 chlorhexidine diacetate Drugs 0.000 claims 8
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 claims 8
- 239000002260 anti-inflammatory agent Substances 0.000 claims 4
- 229940124599 anti-inflammatory drug Drugs 0.000 claims 4
- 239000000017 hydrogel Substances 0.000 claims 4
- 229940127554 medical product Drugs 0.000 claims 4
- 150000007524 organic acids Chemical class 0.000 claims 4
- 238000001035 drying Methods 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 229940100890 silver compound Drugs 0.000 claims 2
- 150000003379 silver compounds Chemical class 0.000 claims 2
- ZXSQEZNORDWBGZ-UHFFFAOYSA-N 1,3-dihydropyrrolo[2,3-b]pyridin-2-one Chemical compound C1=CN=C2NC(=O)CC2=C1 ZXSQEZNORDWBGZ-UHFFFAOYSA-N 0.000 claims 1
- 229920001477 hydrophilic polymer Polymers 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- -1 polytetrafluoroethylene Polymers 0.000 claims 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims 1
- 239000004810 polytetrafluoroethylene Substances 0.000 claims 1
- 229910001958 silver carbonate Inorganic materials 0.000 claims 1
- LKZMBDSASOBTPN-UHFFFAOYSA-L silver carbonate Substances [Ag].[O-]C([O-])=O LKZMBDSASOBTPN-UHFFFAOYSA-L 0.000 claims 1
- 229960003600 silver sulfadiazine Drugs 0.000 claims 1
- UEJSSZHHYBHCEL-UHFFFAOYSA-N silver(1+) sulfadiazinate Chemical compound [Ag+].C1=CC(N)=CC=C1S(=O)(=O)[N-]C1=NC=CC=N1 UEJSSZHHYBHCEL-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/746,670 US7329412B2 (en) | 2000-12-22 | 2000-12-22 | Antimicrobial medical devices containing chlorhexidine free base and salt |
| PCT/US2001/049205 WO2002051464A2 (en) | 2000-12-22 | 2001-12-21 | Antimicrobial medical devices |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004523267A JP2004523267A (ja) | 2004-08-05 |
| JP2004523267A5 true JP2004523267A5 (enExample) | 2005-05-26 |
Family
ID=25001831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002552605A Pending JP2004523267A (ja) | 2000-12-22 | 2001-12-21 | 抗菌性医用装置 |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US7329412B2 (enExample) |
| EP (1) | EP1343547B1 (enExample) |
| JP (1) | JP2004523267A (enExample) |
| AT (1) | ATE428456T1 (enExample) |
| AU (1) | AU2002231069B2 (enExample) |
| CA (2) | CA2784754C (enExample) |
| DE (1) | DE60138412D1 (enExample) |
| ES (1) | ES2327492T3 (enExample) |
| WO (1) | WO2002051464A2 (enExample) |
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-
2000
- 2000-12-22 US US09/746,670 patent/US7329412B2/en not_active Expired - Fee Related
-
2001
- 2001-12-21 AU AU2002231069A patent/AU2002231069B2/en not_active Expired
- 2001-12-21 CA CA2784754A patent/CA2784754C/en not_active Expired - Lifetime
- 2001-12-21 WO PCT/US2001/049205 patent/WO2002051464A2/en not_active Ceased
- 2001-12-21 EP EP01991336A patent/EP1343547B1/en not_active Expired - Lifetime
- 2001-12-21 CA CA2432915A patent/CA2432915C/en not_active Expired - Lifetime
- 2001-12-21 ES ES01991336T patent/ES2327492T3/es not_active Expired - Lifetime
- 2001-12-21 AT AT01991336T patent/ATE428456T1/de not_active IP Right Cessation
- 2001-12-21 JP JP2002552605A patent/JP2004523267A/ja active Pending
- 2001-12-21 DE DE60138412T patent/DE60138412D1/de not_active Expired - Lifetime
-
2003
- 2003-06-20 US US10/600,257 patent/US7537779B2/en not_active Expired - Fee Related
-
2007
- 2007-11-28 US US11/946,622 patent/US8383143B2/en not_active Expired - Fee Related
-
2013
- 2013-02-04 US US13/758,686 patent/US8906401B2/en not_active Expired - Fee Related
-
2014
- 2014-12-01 US US14/557,160 patent/US20150087716A1/en not_active Abandoned
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