JP2004523217A5 - - Google Patents
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- JP2004523217A5 JP2004523217A5 JP2002545150A JP2002545150A JP2004523217A5 JP 2004523217 A5 JP2004523217 A5 JP 2004523217A5 JP 2002545150 A JP2002545150 A JP 2002545150A JP 2002545150 A JP2002545150 A JP 2002545150A JP 2004523217 A5 JP2004523217 A5 JP 2004523217A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- cell
- undifferentiated
- population
- expressed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 210000004027 cell Anatomy 0.000 description 45
- 150000007523 nucleic acids Chemical class 0.000 description 12
- 230000001665 lethal effect Effects 0.000 description 11
- 210000000130 stem cell Anatomy 0.000 description 11
- 238000000034 method Methods 0.000 description 7
- 108091028043 Nucleic acid sequence Proteins 0.000 description 6
- 108020004707 nucleic acids Proteins 0.000 description 6
- 102000039446 nucleic acids Human genes 0.000 description 6
- 239000003795 chemical substances by application Substances 0.000 description 5
- 108010017842 Telomerase Proteins 0.000 description 4
- 102100032938 Telomerase reverse transcriptase Human genes 0.000 description 4
- 108700029229 Transcriptional Regulatory Elements Proteins 0.000 description 4
- 230000006907 apoptotic process Effects 0.000 description 4
- 230000000779 depleting effect Effects 0.000 description 4
- 229940002612 prodrug Drugs 0.000 description 4
- 239000000651 prodrug Substances 0.000 description 4
- 230000022532 regulation of transcription, DNA-dependent Effects 0.000 description 4
- 241000288906 Primates Species 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000006601 Thymidine Kinase Human genes 0.000 description 2
- 108020004440 Thymidine kinase Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 108700012359 toxins Proteins 0.000 description 2
- 206010059866 Drug resistance Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 210000001130 astrocyte Anatomy 0.000 description 1
- 210000004413 cardiac myocyte Anatomy 0.000 description 1
- IRSCQMHQWWYFCW-UHFFFAOYSA-N ganciclovir Chemical compound O=C1NC(N)=NC2=C1N=CN2COC(CO)CO IRSCQMHQWWYFCW-UHFFFAOYSA-N 0.000 description 1
- 229960002963 ganciclovir Drugs 0.000 description 1
- 210000003494 hepatocyte Anatomy 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 231100000518 lethal Toxicity 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 210000004248 oligodendroglia Anatomy 0.000 description 1
- 210000000963 osteoblast Anatomy 0.000 description 1
- 210000001778 pluripotent stem cell Anatomy 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25335700P | 2000-11-27 | 2000-11-27 | |
| US25344300P | 2000-11-27 | 2000-11-27 | |
| US09/783,203 US6576464B2 (en) | 2000-11-27 | 2001-02-13 | Methods for providing differentiated stem cells |
| PCT/US2001/044309 WO2002042445A2 (en) | 2000-11-27 | 2001-11-26 | Differentiated cells suitable for human therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004523217A JP2004523217A (ja) | 2004-08-05 |
| JP2004523217A5 true JP2004523217A5 (https=) | 2005-05-26 |
Family
ID=27400669
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002545150A Pending JP2004523217A (ja) | 2000-11-27 | 2001-11-26 | ヒトの治療に適した分化細胞 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US6576464B2 (https=) |
| EP (1) | EP1337632B1 (https=) |
| JP (1) | JP2004523217A (https=) |
| KR (1) | KR20030081334A (https=) |
| CN (2) | CN101928692A (https=) |
| AU (2) | AU3768102A (https=) |
| CA (1) | CA2434760C (https=) |
| ES (1) | ES2544942T3 (https=) |
| GB (1) | GB2386120B (https=) |
| IL (2) | IL155695A0 (https=) |
| WO (1) | WO2002042445A2 (https=) |
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2001
- 2001-02-13 US US09/783,203 patent/US6576464B2/en not_active Expired - Lifetime
- 2001-11-26 CN CN2009102249802A patent/CN101928692A/zh active Pending
- 2001-11-26 WO PCT/US2001/044309 patent/WO2002042445A2/en not_active Ceased
- 2001-11-26 GB GB0313389A patent/GB2386120B/en not_active Expired - Fee Related
- 2001-11-26 CA CA 2434760 patent/CA2434760C/en not_active Expired - Fee Related
- 2001-11-26 IL IL15569501A patent/IL155695A0/xx active IP Right Grant
- 2001-11-26 CN CNA018196470A patent/CN1478145A/zh active Pending
- 2001-11-26 KR KR10-2003-7007100A patent/KR20030081334A/ko not_active Withdrawn
- 2001-11-26 JP JP2002545150A patent/JP2004523217A/ja active Pending
- 2001-11-26 AU AU3768102A patent/AU3768102A/xx active Pending
- 2001-11-26 ES ES01986488.3T patent/ES2544942T3/es not_active Expired - Lifetime
- 2001-11-26 EP EP01986488.3A patent/EP1337632B1/en not_active Expired - Lifetime
- 2001-11-26 AU AU2002237681A patent/AU2002237681B2/en not_active Ceased
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2002
- 2002-05-07 US US10/141,220 patent/US20030040111A1/en not_active Abandoned
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2003
- 2003-04-30 IL IL155695A patent/IL155695A/en not_active IP Right Cessation
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- 2006-02-21 US US11/359,341 patent/US8426198B2/en not_active Expired - Fee Related
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