JP2004521607A - ケモカイン、神経ペプチド前駆体または少なくとも一つの神経ペプチドをコードする核酸配列を含んでなる核酸分子 - Google Patents

ケモカイン、神経ペプチド前駆体または少なくとも一つの神経ペプチドをコードする核酸配列を含んでなる核酸分子 Download PDF

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JP2004521607A
JP2004521607A JP2002500722A JP2002500722A JP2004521607A JP 2004521607 A JP2004521607 A JP 2004521607A JP 2002500722 A JP2002500722 A JP 2002500722A JP 2002500722 A JP2002500722 A JP 2002500722A JP 2004521607 A JP2004521607 A JP 2004521607A
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nucleic acid
sdf
seq
acid sequence
fragment
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JP2004521607A5 (enExample
Inventor
ハンス、ベルナー、ミューラー
フランク、ボッセ
マルク、グライヒマン
クレメンス、ギレン
ヨハネス、アウエル
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NEURAXO BIOTEC GmbH
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NEURAXO BIOTEC GmbH
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • C07K14/522Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4, KC
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2002500722A 2000-06-02 2001-06-01 ケモカイン、神経ペプチド前駆体または少なくとも一つの神経ペプチドをコードする核酸配列を含んでなる核酸分子 Pending JP2004521607A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10027383A DE10027383A1 (de) 2000-06-02 2000-06-02 Nukleinsäure-Molekül umfassend eine für ein Chemokin, einen Neuropeptid-Präkursor oder mindestens ein Neuropeptid kodierende Nukleinsäuresequenz
PCT/EP2001/006250 WO2001092530A1 (de) 2000-06-02 2001-06-01 Nukleinsäure-molekül umfassend eine für ein sdf-1 gamma chemokin, einen neuropeptid-präkursor oder mindestens ein neuropeptid kodierende nukleinsäuresequenz

Publications (2)

Publication Number Publication Date
JP2004521607A true JP2004521607A (ja) 2004-07-22
JP2004521607A5 JP2004521607A5 (enExample) 2005-02-17

Family

ID=7644466

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002500722A Pending JP2004521607A (ja) 2000-06-02 2001-06-01 ケモカイン、神経ペプチド前駆体または少なくとも一つの神経ペプチドをコードする核酸配列を含んでなる核酸分子

Country Status (9)

Country Link
US (2) US20030215792A1 (enExample)
EP (1) EP1287142B1 (enExample)
JP (1) JP2004521607A (enExample)
AT (1) ATE309361T1 (enExample)
AU (1) AU6233501A (enExample)
DE (2) DE10027383A1 (enExample)
DK (1) DK1287142T3 (enExample)
ES (1) ES2251483T3 (enExample)
WO (1) WO2001092530A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004232972A1 (en) * 2003-04-16 2004-11-04 Argyll Biotechnologies, Llc Prophylactic and therapeutic benefits of new class of immune stimulating peptides
WO2006124013A2 (en) * 2004-04-30 2006-11-23 Five Prime Therapeutics, Inc. Novel stromal cell-derived factor-1 polypeptides, polynucleotides, modulators thereof, and method of use
UA96926C2 (ru) * 2005-10-31 2011-12-26 Мерк Сероно Са Применение sdf-1 для лечения и/или профилактики неврологических заболеваний
AU2007237840A1 (en) * 2006-04-07 2007-10-25 Neuro Therapeutics Ab Survival and development of neural cells
WO2008003780A2 (en) * 2006-07-07 2008-01-10 TRÖSCHER, Herbert Use of proteins of the sdf-1-family for improvement of axonal plasticity or for axonal regeneration following lesions
US7696309B2 (en) 2006-10-23 2010-04-13 The Brigham And Women's Hospital, Inc. Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage
EP2197907A2 (en) * 2007-10-15 2010-06-23 Centre National De La Recherche Scientifique-CNRS Cxcl12 gamma a chemokine and uses thereof
US9308277B2 (en) 2010-02-25 2016-04-12 Mesoblast International Sàrl Protease-resistant mutants of stromal cell derived factor-1 in the repair of tissue damage
US10662234B2 (en) 2011-06-07 2020-05-26 Mesoblast International Sàrl Methods for repairing tissue damage using protease-resistant mutants of stromal cell derived factor-1

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
US5885794A (en) * 1991-05-10 1999-03-23 The Salk Institute For Biological Studies Recombinant production of vertebrate activin receptor polypeptides and identification of receptor DNAs in the activin/TGF-β superfamily
CA2117953C (en) * 1993-10-14 2001-12-11 Tasuku Honjo Human stromal derived factor 1 alpha and 1 beta and dnas encoding the same
US6114502A (en) * 1996-04-10 2000-09-05 Axys Pharmaceuticals, Inc. Gene family associated with neurosensory defects
EP0892807A1 (en) * 1996-04-10 1999-01-27 Axys Pharmaceuticals, Inc. Gene family associated with neurosensory defects
US6100387A (en) * 1997-02-28 2000-08-08 Genetics Institute, Inc. Chimeric polypeptides containing chemokine domains
MXPA00003885A (es) * 1997-10-22 2004-04-23 Inst Genetics Llc Quimiocinas con modificiaciones de la terminacion amino.
US6747137B1 (en) * 1998-02-13 2004-06-08 Genome Therapeutics Corporation Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics
WO1999055915A2 (en) * 1998-04-29 1999-11-04 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services IDENTIFICATION OF POLYMORPHISMS IN THE PCTG4 REGION OF Xq13
AU5134799A (en) * 1998-07-30 2000-02-21 Human Genome Sciences, Inc. 98 human secreted proteins
AU2201801A (en) * 1999-12-16 2001-06-25 Ribotargets Limited Assays

Also Published As

Publication number Publication date
EP1287142A1 (de) 2003-03-05
WO2001092530A1 (de) 2001-12-06
AU6233501A (en) 2001-12-11
EP1287142B1 (de) 2005-11-09
DK1287142T3 (da) 2006-03-13
US20030215792A1 (en) 2003-11-20
US20080319165A1 (en) 2008-12-25
DE50108009D1 (de) 2005-12-15
ATE309361T1 (de) 2005-11-15
ES2251483T3 (es) 2006-05-01
DE10027383A1 (de) 2001-12-20

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