JP2004519450A5 - - Google Patents
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- Publication number
- JP2004519450A5 JP2004519450A5 JP2002552911A JP2002552911A JP2004519450A5 JP 2004519450 A5 JP2004519450 A5 JP 2004519450A5 JP 2002552911 A JP2002552911 A JP 2002552911A JP 2002552911 A JP2002552911 A JP 2002552911A JP 2004519450 A5 JP2004519450 A5 JP 2004519450A5
- Authority
- JP
- Japan
- Prior art keywords
- hal
- carbon atoms
- alkenyl
- substituted
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000004432 carbon atom Chemical group C* 0.000 description 10
- 125000003342 alkenyl group Chemical group 0.000 description 4
- 125000000217 alkyl group Chemical group 0.000 description 4
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 description 2
- 101100167365 Caenorhabditis elegans cha-1 gene Proteins 0.000 description 2
- 125000001309 chloro group Chemical group Cl* 0.000 description 2
- 125000000753 cycloalkyl group Chemical group 0.000 description 2
- 125000002993 cycloalkylene group Chemical group 0.000 description 2
- 125000001153 fluoro group Chemical group F* 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 239000012453 solvate Substances 0.000 description 2
- -1 COOA 1 Chemical group 0.000 description 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 description 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10064997A DE10064997A1 (de) | 2000-12-23 | 2000-12-23 | Benzoylpyridazine |
| PCT/EP2001/015070 WO2002051814A1 (en) | 2000-12-23 | 2001-12-19 | Benzoylpyridazines |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004519450A JP2004519450A (ja) | 2004-07-02 |
| JP2004519450A5 true JP2004519450A5 (https=) | 2009-03-05 |
| JP4532071B2 JP4532071B2 (ja) | 2010-08-25 |
Family
ID=7668970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002552911A Expired - Fee Related JP4532071B2 (ja) | 2000-12-23 | 2001-12-19 | ベンゾイルピリダジン |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7312328B2 (https=) |
| EP (1) | EP1343769B1 (https=) |
| JP (1) | JP4532071B2 (https=) |
| KR (1) | KR20030065564A (https=) |
| CN (1) | CN1483026A (https=) |
| AR (1) | AR032010A1 (https=) |
| AT (1) | ATE476423T1 (https=) |
| BR (1) | BR0116304A (https=) |
| CA (1) | CA2432568C (https=) |
| CZ (1) | CZ20031860A3 (https=) |
| DE (2) | DE10064997A1 (https=) |
| ES (1) | ES2349622T3 (https=) |
| HU (1) | HUP0302562A2 (https=) |
| MX (1) | MXPA03005494A (https=) |
| NO (1) | NO20032862L (https=) |
| PL (1) | PL364229A1 (https=) |
| RU (1) | RU2003122188A (https=) |
| SK (1) | SK8662003A3 (https=) |
| WO (1) | WO2002051814A1 (https=) |
| ZA (1) | ZA200305661B (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003300076C1 (en) | 2002-12-30 | 2010-03-04 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
| PE20060272A1 (es) * | 2004-05-24 | 2006-05-22 | Glaxo Group Ltd | (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a |
| GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
| TWI546537B (zh) * | 2009-05-19 | 2016-08-21 | 維維亞生技公司 | 提供針對血液腫瘤之體外個人化藥物測試之方法 |
| US10806711B2 (en) | 2011-08-12 | 2020-10-20 | University Of Cincinnati | Method of treating acute decompensated heart failure with probenecid |
| AU2014244053B2 (en) | 2013-03-13 | 2018-08-30 | University Of Cincinnati | Treatment of a diastolic cardiac dysfunction with a TRPV2 receptor agonist |
| WO2016149126A1 (en) | 2015-03-13 | 2016-09-22 | The Board Of Trustees Of The Leland Stanford Junior University | Ltb4 inhibition to prevent and treat human lymphedema |
| CN105175283A (zh) * | 2015-09-23 | 2015-12-23 | 蚌埠中实化学技术有限公司 | 一种3-乙氧基-4-甲氧基苯腈的制备方法 |
| US11116737B1 (en) | 2020-04-10 | 2021-09-14 | University Of Georgia Research Foundation, Inc. | Methods of using probenecid for treatment of coronavirus infections |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT68424A (en) * | 1992-07-01 | 1995-06-28 | Ortho Pharma Corp | Novel 1-arylsulphonyl-, -arylcarbonyl- and 1-arylphosphonyl-3-phenyl-1,4,5,6-tetrahydro-pyridazines |
| EP0738268B1 (en) | 1993-12-22 | 2004-03-03 | Celltech R&D Limited | Trisubstituted phenyl derivatives, processes for their preparation and their use as phosphodiesterase (type iv) inhibitors |
| US5786354A (en) | 1994-06-21 | 1998-07-28 | Celltech Therapeutics, Limited | Tri-substituted phenyl derivatives and processes for their preparation |
| GB9412672D0 (en) | 1994-06-23 | 1994-08-10 | Celltech Ltd | Chemical compounds |
| DE19514568A1 (de) * | 1995-04-20 | 1996-10-24 | Merck Patent Gmbh | Arylalkyl-pyridazinone |
| DE19533975A1 (de) * | 1995-09-14 | 1997-03-20 | Merck Patent Gmbh | Arylalkyl-diazinone |
| GB9525262D0 (en) | 1995-12-11 | 1996-02-07 | Bayer Ag | Heterocyclylcarbonyl substituted benzofuranyl-ureas |
| DE19632549A1 (de) | 1996-08-13 | 1998-02-19 | Merck Patent Gmbh | Arylalkanoylpyridazine |
| DE19826841A1 (de) * | 1998-06-16 | 1999-12-23 | Merck Patent Gmbh | Arylalkanoylpyridazine |
| DE19850701A1 (de) * | 1998-11-04 | 2000-05-11 | Merck Patent Gmbh | Benzoylpyridazine |
-
2000
- 2000-12-23 DE DE10064997A patent/DE10064997A1/de not_active Withdrawn
-
2001
- 2001-12-19 AR ARP010105890A patent/AR032010A1/es unknown
- 2001-12-19 KR KR10-2003-7008423A patent/KR20030065564A/ko not_active Withdrawn
- 2001-12-19 CN CNA018211763A patent/CN1483026A/zh active Pending
- 2001-12-19 CZ CZ20031860A patent/CZ20031860A3/cs unknown
- 2001-12-19 CA CA2432568A patent/CA2432568C/en not_active Expired - Fee Related
- 2001-12-19 DE DE60142749T patent/DE60142749D1/de not_active Expired - Lifetime
- 2001-12-19 US US10/451,393 patent/US7312328B2/en not_active Expired - Fee Related
- 2001-12-19 MX MXPA03005494A patent/MXPA03005494A/es unknown
- 2001-12-19 WO PCT/EP2001/015070 patent/WO2002051814A1/en not_active Ceased
- 2001-12-19 ES ES01272031T patent/ES2349622T3/es not_active Expired - Lifetime
- 2001-12-19 AT AT01272031T patent/ATE476423T1/de not_active IP Right Cessation
- 2001-12-19 JP JP2002552911A patent/JP4532071B2/ja not_active Expired - Fee Related
- 2001-12-19 HU HU0302562A patent/HUP0302562A2/hu unknown
- 2001-12-19 BR BR0116304-3A patent/BR0116304A/pt not_active Application Discontinuation
- 2001-12-19 SK SK866-2003A patent/SK8662003A3/sk unknown
- 2001-12-19 RU RU2003122188/04A patent/RU2003122188A/ru not_active Application Discontinuation
- 2001-12-19 EP EP01272031A patent/EP1343769B1/en not_active Expired - Lifetime
- 2001-12-19 PL PL01364229A patent/PL364229A1/xx unknown
-
2003
- 2003-06-20 NO NO20032862A patent/NO20032862L/no not_active Application Discontinuation
- 2003-07-22 ZA ZA200305661A patent/ZA200305661B/en unknown