JP2004518639A5 - - Google Patents

Info

Publication number

JP2004518639A5

JP2004518639A5 JP2002544012A JP2002544012A JP2004518639A5 JP 2004518639 A5 JP2004518639 A5 JP 2004518639A5 JP 2002544012 A JP2002544012 A JP 2002544012A JP 2002544012 A JP2002544012 A JP 2002544012A JP 2004518639 A5 JP2004518639 A5 JP 2004518639A5

Authority

JP

Japan

Prior art keywords

alkyl

linear

branched

group

hydrogen

Prior art date

2001-11-21

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
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• 125000000217 alkyl group Chemical group 0.000 claims 61
• UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 22
• 229910052739 hydrogen Inorganic materials 0.000 claims 22
• 239000001257 hydrogen Substances 0.000 claims 22
• 125000000304 alkynyl group Chemical group 0.000 claims 14
• 150000001875 compounds Chemical class 0.000 claims 14
• 125000003342 alkenyl group Chemical group 0.000 claims 13
• -1 acetoxymethyl Chemical group 0.000 claims 12
• 150000002148 esters Chemical class 0.000 claims 11
• 229960000367 inositol Drugs 0.000 claims 8
• 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 7
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 7
• 150000003839 salts Chemical class 0.000 claims 7
• NFHFRUOZVGFOOS-UHFFFAOYSA-N palladium;triphenylphosphane Chemical compound [Pd].C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1.C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1.C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1.C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1 NFHFRUOZVGFOOS-UHFFFAOYSA-N 0.000 claims 5
• 229910019142 PO4 Inorganic materials 0.000 claims 4
• 229910052736 halogen Inorganic materials 0.000 claims 4
• 150000002367 halogens Chemical class 0.000 claims 4
• NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 4
• 239000010452 phosphate Substances 0.000 claims 4
• 239000000126 substance Substances 0.000 claims 4
• VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 3
• 206010061218 Inflammation Diseases 0.000 claims 3
• 230000004054 inflammatory process Effects 0.000 claims 3
• 230000028327 secretion Effects 0.000 claims 3
• 239000003814 drug Substances 0.000 claims 2
• HOXINJBQVZWYGZ-UHFFFAOYSA-N fenbutatin oxide Chemical compound C=1C=CC=CC=1C(C)(C)C[Sn](O[Sn](CC(C)(C)C=1C=CC=CC=1)(CC(C)(C)C=1C=CC=CC=1)CC(C)(C)C=1C=CC=CC=1)(CC(C)(C)C=1C=CC=CC=1)CC(C)(C)C1=CC=CC=C1 HOXINJBQVZWYGZ-UHFFFAOYSA-N 0.000 claims 2
• 230000002401 inhibitory effect Effects 0.000 claims 2
• 230000001105 regulatory effect Effects 0.000 claims 2
• 239000001226 triphosphate Substances 0.000 claims 2
• SQUHHTBVTRBESD-UHFFFAOYSA-N Hexa-Ac-myo-Inositol Natural products CC(=O)OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O SQUHHTBVTRBESD-UHFFFAOYSA-N 0.000 claims 1
• HZTJDBWXSVQJFY-UHFFFAOYSA-N [acetyloxymethoxy-[[4,6,7-tris[bis(acetyloxymethoxy)phosphoryloxy]-2,2-dimethyl-7a-propyl-4,5,6,7-tetrahydro-3aH-1,3-benzodioxol-5-yl]oxy]phosphoryl]oxymethyl acetate Chemical compound C(C)(=O)OCOP(=O)(OCOC(C)=O)OC1C(C(C(C2OC(OC21CCC)(C)C)OP(=O)(OCOC(C)=O)OCOC(C)=O)OP(=O)(OCOC(C)=O)OCOC(C)=O)OP(=O)(OCOC(C)=O)OCOC(C)=O HZTJDBWXSVQJFY-UHFFFAOYSA-N 0.000 claims 1
• 230000033228 biological regulation Effects 0.000 claims 1
• 238000006243 chemical reaction Methods 0.000 claims 1
• 125000004122 cyclic group Chemical group 0.000 claims 1
• 230000005764 inhibitory process Effects 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• LFGREXWGYUGZLY-UHFFFAOYSA-N phosphoryl Chemical group [P]=O LFGREXWGYUGZLY-UHFFFAOYSA-N 0.000 claims 1
• CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 claims 1