JP2004512258A - 生物系における細胞応答の調節のための方法および試薬 - Google Patents

生物系における細胞応答の調節のための方法および試薬 Download PDF

Info

Publication number
JP2004512258A
JP2004512258A JP2001569247A JP2001569247A JP2004512258A JP 2004512258 A JP2004512258 A JP 2004512258A JP 2001569247 A JP2001569247 A JP 2001569247A JP 2001569247 A JP2001569247 A JP 2001569247A JP 2004512258 A JP2004512258 A JP 2004512258A
Authority
JP
Japan
Prior art keywords
cell
ligand
sre
multivalent ligand
multivalent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2001569247A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004512258A5 (enExample
Inventor
キースリング, ローラ エル.
ストロング, ローラ イー.
ゲストウィッキ, ジェイソン イー.
Original Assignee
ウィスコンシン アルムニ リサーチ ファンデイション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ウィスコンシン アルムニ リサーチ ファンデイション filed Critical ウィスコンシン アルムニ リサーチ ファンデイション
Publication of JP2004512258A publication Critical patent/JP2004512258A/ja
Publication of JP2004512258A5 publication Critical patent/JP2004512258A5/ja
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/178Lectin superfamily, e.g. selectins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
JP2001569247A 2000-03-21 2001-03-21 生物系における細胞応答の調節のための方法および試薬 Withdrawn JP2004512258A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19101400P 2000-03-21 2000-03-21
PCT/US2001/009174 WO2001071309A2 (en) 2000-03-21 2001-03-21 Methods and reagents for regulation of cellular responses in biological systems

Publications (2)

Publication Number Publication Date
JP2004512258A true JP2004512258A (ja) 2004-04-22
JP2004512258A5 JP2004512258A5 (enExample) 2008-05-22

Family

ID=22703769

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001569247A Withdrawn JP2004512258A (ja) 2000-03-21 2001-03-21 生物系における細胞応答の調節のための方法および試薬

Country Status (6)

Country Link
US (2) US20030125262A1 (enExample)
EP (1) EP1334118A4 (enExample)
JP (1) JP2004512258A (enExample)
AU (2) AU8149901A (enExample)
CA (1) CA2403669A1 (enExample)
WO (1) WO2001071309A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006347908A (ja) * 2005-06-14 2006-12-28 National Institute Of Advanced Industrial & Technology シアル酸含有3糖化合物、それを用いるサーズウイルスまたはサーズスパイク蛋白質の検出

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8149901A (en) * 2000-03-21 2001-10-03 Wisconsin Alummi Res Foundatio Methods and reagents for regulation of cellular responses in biological systems
US20040248801A1 (en) * 2000-03-21 2004-12-09 Kiessling Laura L. Methods and reagents for regulation of cellular responses in biological systems
EP1625156B1 (en) * 2003-05-12 2012-09-19 Affymax, Inc. Peptides that bind to the erythropoietin receptor
AU2004238870B8 (en) * 2003-05-12 2010-04-15 Affymax, Inc. Novel peptides that bind to the erythropoietin receptor
JP2007500218A (ja) 2003-05-12 2007-01-11 アフィーマックス・インコーポレイテッド ポリ(エチレングリコール)修飾ペプチド系化合物の新規スペーサー部分
EP1626983B8 (en) * 2003-05-12 2010-12-22 Affymax, Inc. Novel poly (ethylene glycol) modified erythropoietin agonists and uses thereof
KR20070108140A (ko) * 2004-11-11 2007-11-08 아피맥스, 인크. 에리트로포이에틴 수용체에 결합하는 신규한 펩타이드
WO2006062685A2 (en) * 2004-11-11 2006-06-15 Affymax, Inc. Novel peptides that bind to the erythropoietin receptor
GB0426822D0 (en) * 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
GB0426823D0 (en) * 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
US7550433B2 (en) 2005-06-03 2009-06-23 Affymax, Inc. Erythropoietin receptor peptide formulations and uses
US7919461B2 (en) 2005-06-03 2011-04-05 Affymax, Inc. Erythropoietin receptor peptide formulations and uses
US8324159B2 (en) * 2005-06-03 2012-12-04 Affymax, Inc. Erythropoietin receptor peptide formulations and uses
WO2007131084A2 (en) 2006-05-03 2007-11-15 Wisconsin Alumni Research Foundation Magnetic resonance imaging contrast agents synthesized using ring-opening metathesis polymerization
EP2139524A1 (en) * 2007-03-23 2010-01-06 The Governors of the University of Alberta Multivalent heterobifunctional polymers and methods of their use
US9029332B2 (en) 2010-12-15 2015-05-12 The Research Foundation For The State University Of New York Cross-linked peptides and proteins, methods of making same, and uses thereof
US20140350370A1 (en) * 2013-04-08 2014-11-27 The Texas A&M University System Glucose sensing assay
WO2018200951A1 (en) * 2017-04-28 2018-11-01 Tran David T Multi-targeted multi-valent ligand-drug particles for the treatment and prevention of diseases and conditions

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4427660A (en) * 1982-03-03 1984-01-24 Research Corporation Formyl-methionyl chemotatic peptide antibiotic conjugates useful in treating infections
US4883851A (en) * 1988-07-25 1989-11-28 California Institute Of Technology Ring opening metathesis polymerization of strained cyclic ethers
US5100972A (en) * 1990-07-16 1992-03-31 General Electric Company Cycloalkene terminated polyarylene ether
US5641622A (en) * 1990-09-13 1997-06-24 Baxter International Inc. Continuous centrifugation process for the separation of biological components from heterogeneous cell populations
EP0773948A4 (en) * 1992-04-03 1998-09-02 California Inst Of Techn HIGHLY ACTIVE RUTHENIUM OR OSMIUM METAL CARBEN COMPLEXES FOR OLEFIN METHETHESE REACTIONS AND THEIR SYNTHESIS
US5312940A (en) * 1992-04-03 1994-05-17 California Institute Of Technology Ruthenium and osmium metal carbene complexes for olefin metathesis polymerization
US5710298A (en) * 1992-04-03 1998-01-20 California Institute Of Technology Method of preparing ruthenium and osmium carbene complexes
US5599912A (en) * 1993-09-10 1997-02-04 Coretech, Inc. Compounds and methods for suppressing an immune response to sulfomethoxozale containing substances
US5587442A (en) * 1994-12-23 1996-12-24 Kiessling; Laura L. Polyglycomers
US5831108A (en) * 1995-08-03 1998-11-03 California Institute Of Technology High metathesis activity ruthenium and osmium metal carbene complexes
US6060570A (en) * 1996-08-12 2000-05-09 Bp Amoco Corporation Process for preparation of addition products of difunctional telechelic polyolefins from cyclic olefins by olefin metathesis reaction
US6080826A (en) * 1997-01-06 2000-06-27 California Institute Of Technology Template-directed ring-closing metathesis and ring-opening metathesis polymerization of functionalized dienes
US5889128A (en) * 1997-04-11 1999-03-30 Massachusetts Institute Of Technology Living olefin polymerization processes
DE19742980A1 (de) * 1997-09-29 1999-04-01 Espe Dental Ag Dentalmassen auf der Basis von ROMP-Oligomeren oder -Polymeren
US6121236A (en) * 1998-03-24 2000-09-19 The Children's Medical Center Corporation Multivalent ligands which modulate angiogenesis
US6437119B1 (en) * 1998-05-07 2002-08-20 William Lawrence Truett Compounds formed from two or three antibiotics and their processes of preparation
US6280527B1 (en) * 1998-06-12 2001-08-28 International Business Machines Corporation Aqueous quaternary ammonium hydroxide as a screening mask cleaner
US6271315B1 (en) * 1999-06-17 2001-08-07 Wisconsin Alumni Research Foundation Methods for making multivalent arrays
US6291616B1 (en) * 1999-06-17 2001-09-18 Wisconsin Alumni Research Foundation Methods and reagents for capping ruthenium or osmium carbene-catalyzed ROMP products
HUP9902217A3 (en) * 1999-06-29 2002-07-29 Szegoe Peter Polycation based bioconjugates and process for producing thereof
GB9916235D0 (en) * 1999-07-09 1999-09-15 Univ Durham Process for polymerisation of olefins and novel polymerisable olefins
US20040248801A1 (en) * 2000-03-21 2004-12-09 Kiessling Laura L. Methods and reagents for regulation of cellular responses in biological systems
AU8149901A (en) * 2000-03-21 2001-10-03 Wisconsin Alummi Res Foundatio Methods and reagents for regulation of cellular responses in biological systems
WO2007131084A2 (en) * 2006-05-03 2007-11-15 Wisconsin Alumni Research Foundation Magnetic resonance imaging contrast agents synthesized using ring-opening metathesis polymerization

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006347908A (ja) * 2005-06-14 2006-12-28 National Institute Of Advanced Industrial & Technology シアル酸含有3糖化合物、それを用いるサーズウイルスまたはサーズスパイク蛋白質の検出

Also Published As

Publication number Publication date
WO2001071309A2 (en) 2001-09-27
EP1334118A4 (en) 2005-10-05
US20030125262A1 (en) 2003-07-03
EP1334118A2 (en) 2003-08-13
US20070270351A1 (en) 2007-11-22
AU8149901A (en) 2001-10-03
CA2403669A1 (en) 2001-09-27
WO2001071309A3 (en) 2003-05-15
AU2001281499B2 (en) 2007-01-04

Similar Documents

Publication Publication Date Title
JP2004512258A (ja) 生物系における細胞応答の調節のための方法および試薬
US20100104585A1 (en) Methods and Reagents for Regulation of Cellular Responses in Biological Systems
JP4467882B2 (ja) ナノ粒子
Gao et al. Exploring and controlling the polymorphism in supramolecular assemblies of carbohydrates and proteins
US5212075A (en) Compositions and methods for introducing effectors to pathogens and cells
Ilk et al. S-layer fusion proteins—construction principles and applications
AU754331B2 (en) Treatment of bacterial infections
AU2001281499A1 (en) Methods and reagents for regulation of cellular responses in biological systems
JPH11502817A (ja) 所定のペプチド特異性のマイクロカプセル、それらの調製および使用
EP1425306A2 (de) Nanopartikel mit daran immobilisiertem biologisch aktivem tnf
KR20010006280A (ko) 다수개의 활성 잔기를 제공하는 분자
JP2010521526A (ja) 多価ヘテロ二官能性ポリマーおよびその使用方法
CN1298306A (zh) 艰难梭菌毒素b相关疾病的治疗
US5962423A (en) Treatment of bacterial dysentery
WO1998026662A1 (en) Compounds and methods for treating and preventing bacterial and viral disease
WO1998026662A9 (en) Compounds and methods for treating and preventing bacterial and viral disease
US5888750A (en) Method of recovering shiga-like toxins and vaccines comprising inactivated shiga-like toxin
Üclü et al. Sweet Janus Particles: Multifunctional Inhibitors of Carbohydrate-Based Bacterial Adhesion
CN116368222A (zh) 破坏cd28-唾液酸糖苷配体复合物以增强t细胞活化
JP2001503436A (ja) サッカライド誘導体
JPH107575A (ja) 細菌性赤痢の処置
JP2001505558A (ja) 炭化水素ライブラリーのコンビナトリアル合成
JP3813682B2 (ja) ワクチン前駆体およびワクチン
Vena LEctPROFILE kits: towards quality control and new potential applications
JP4230420B2 (ja) ワクチン前駆体及びワクチン

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080319

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20080319

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20100309

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20100420