JP2004511253A5 - - Google Patents

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Publication number
JP2004511253A5
JP2004511253A5 JP2002536334A JP2002536334A JP2004511253A5 JP 2004511253 A5 JP2004511253 A5 JP 2004511253A5 JP 2002536334 A JP2002536334 A JP 2002536334A JP 2002536334 A JP2002536334 A JP 2002536334A JP 2004511253 A5 JP2004511253 A5 JP 2004511253A5
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JP
Japan
Prior art keywords
papp
polypeptide
seq
amino acids
fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2002536334A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004511253A (ja
JP4460829B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/DK2001/000695 external-priority patent/WO2002032953A2/en
Publication of JP2004511253A publication Critical patent/JP2004511253A/ja
Publication of JP2004511253A5 publication Critical patent/JP2004511253A5/ja
Application granted granted Critical
Publication of JP4460829B2 publication Critical patent/JP4460829B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2002536334A 2000-10-20 2001-10-19 妊娠関連血漿蛋白−ａ２（ｐａｐｐ−ａ２） Expired - Fee Related JP4460829B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24184000P 2000-10-20 2000-10-20
DKPA200001571 2000-10-20
PCT/DK2001/000695 WO2002032953A2 (en) 2000-10-20 2001-10-19 Pregnancy-associated plasma protein-a2 (papp-a2)

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009291514A Division JP5072950B2 (ja) 2000-10-20 2009-12-22 妊娠関連血漿蛋白−ａ２（ｐａｐｐ−ａ２）

Publications (3)

Publication Number Publication Date
JP2004511253A JP2004511253A (ja) 2004-04-15
JP2004511253A5 true JP2004511253A5 (https=) 2007-07-05
JP4460829B2 JP4460829B2 (ja) 2010-05-12

Family

ID=44063430

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2002536334A Expired - Fee Related JP4460829B2 (ja) 2000-10-20 2001-10-19 妊娠関連血漿蛋白−ａ２（ｐａｐｐ−ａ２）
JP2009291514A Expired - Fee Related JP5072950B2 (ja) 2000-10-20 2009-12-22 妊娠関連血漿蛋白−ａ２（ｐａｐｐ−ａ２）
JP2012147230A Pending JP2012229235A (ja) 2000-10-20 2012-06-29 妊娠関連血漿蛋白−ａ２（ｐａｐｐ−ａ２）

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2009291514A Expired - Fee Related JP5072950B2 (ja) 2000-10-20 2009-12-22 妊娠関連血漿蛋白−ａ２（ｐａｐｐ−ａ２）
JP2012147230A Pending JP2012229235A (ja) 2000-10-20 2012-06-29 妊娠関連血漿蛋白−ａ２（ｐａｐｐ−ａ２）

Country Status (6)

Country Link
US (6) US7083940B2 (https=)
EP (2) EP2339020B1 (https=)
JP (3) JP4460829B2 (https=)
AU (1) AU2002210403A1 (https=)
CA (2) CA2464121C (https=)
WO (1) WO2002032953A2 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2464121C (en) * 2000-10-20 2013-08-13 Como Biotech Aps Pregnancy-associated plasma protein-a2 (papp-a2)
AT500321B1 (de) * 2003-12-30 2006-02-15 Red Bull Gmbh Verfahren zur diagnose des down-syndroms
ATE412181T1 (de) * 2004-01-28 2008-11-15 Turun Yliopisto Verbessertes verfahren zur diagnose des akuten koronarsyndroms
US20050277147A1 (en) * 2004-06-11 2005-12-15 Ameet Patki Identifying chromosomal abnormalities in cells obtained from follicular fluid
US20060205651A1 (en) * 2005-02-25 2006-09-14 Royal College Of Surgeons In Ireland Method of treating cancer
CA2601735C (en) * 2005-03-18 2015-10-06 The Chinese University Of Hong Kong Markers for prenatal diagnosis and monitoring of trisomy 21
AU2009207645B2 (en) * 2008-01-25 2014-11-13 Aarhus Universitet Selective exosite inhibition of PAPP-A activity against IGFBP-4
GB0910751D0 (en) 2009-06-23 2009-08-05 Procure Therapeutics Ltd Prostate cancer vaccine
WO2011137266A1 (en) * 2010-04-28 2011-11-03 Watlow Electric Manufacturing Company Flow through heater
WO2011144999A1 (en) * 2010-05-17 2011-11-24 Sandra Reznik Plasma protein-a2 (papp-a2) as a marker for detecting risk of chromosomal abnormalities
EP2766726A1 (en) * 2011-10-14 2014-08-20 Aarhus Universitet Diagnostic and prognostic use of prombp-complexes
EP2861989A4 (en) 2012-06-15 2016-03-02 Univ Wayne State BIOMARK TEST FOR PREDICTING OR EARLY IDENTIFICATION OF PRE-LAMPSY AND / OR HELLP SYNDROME
EP2890816B1 (en) * 2012-08-30 2019-06-05 Ansh Labs LLC Papp-a2 as a marker for monitoring, predicting and diagnosing preeclampsia
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US10543259B2 (en) * 2015-03-02 2020-01-28 Children's Hospital Medical Center Methods and compositions for the identification and treatment of individuals having or likely to develop short stature
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN110194801B (zh) * 2018-02-26 2022-06-14 张灏 一种融合蛋白和多克隆抗体及其应用
US11988674B2 (en) 2018-08-07 2024-05-21 University Of South Carolina Methods for measuring gene expression levels to identify viable oocytes
EP4070113A4 (en) 2019-12-04 2023-12-20 Biora Therapeutics, Inc. ASSESSMENT OF PREECLAMPSIA USING FREE AND DISSOCIATE PLACENTAL GROWTH FACTOR TESTS
TW202432584A (zh) * 2022-11-15 2024-08-16 美商嘉來克生命科學有限責任公司 抗papp-a抗體及其使用方法
TW202528331A (zh) * 2023-11-13 2025-07-16 美商嘉來克生命科學有限責任公司 關於基於肽之ｐａｐｐ－ａ調節劑之組合物及方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL63224A (en) 1980-07-17 1985-05-31 Scripps Clinic Res Synthetic peptide specific antigenic determinant and method of manufacturing antigenic materials therefrom
US4554101A (en) 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US6780613B1 (en) 1988-10-28 2004-08-24 Genentech, Inc. Growth hormone variants
GB9614615D0 (en) 1996-07-11 1996-09-04 Isis Innovation Diagnosis of pre-eclampsia
US6432628B1 (en) * 1997-08-26 2002-08-13 Thomas Jefferson University Caspase-14, an apoptotic protease, nucleic acids encoding and methods of use
DE60034779T2 (de) * 1999-03-15 2008-01-17 Mayo Foundation For Medical Education And Research, Rochester Insulinartiger-wachstumsfaktorbindungsprotein-4-protease
US6436703B1 (en) * 2000-03-31 2002-08-20 Hyseq, Inc. Nucleic acids and polypeptides
US6656700B2 (en) 2000-05-26 2003-12-02 Amersham Plc Isoforms of human pregnancy-associated protein-E
AU7410701A (en) * 2000-06-16 2001-12-24 Martin Farr Pregnancy-associated plasma protein-e (papp-e)
CA2464121C (en) * 2000-10-20 2013-08-13 Como Biotech Aps Pregnancy-associated plasma protein-a2 (papp-a2)
US6500630B2 (en) * 2001-01-12 2002-12-31 Mayo Foundation For Medical Education And Research Marker for inflammatory conditions
WO2006138696A2 (en) * 2005-06-17 2006-12-28 Genizon Biosciences, Inc. Genemap of the human genes associated with longevity
US20080071151A1 (en) * 2006-06-30 2008-03-20 Sogin David C Method and Apparatus for Diagnosing Pre-eclampsia
ES2587077T3 (es) * 2008-01-25 2016-10-20 Wallac Oy Métodos para determinar el riesgo de anomalías cromosómicas en un feto

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