JP2004510695A - コリン作動薬および迷走神経刺激による炎症性サイトカイン産生の阻害 - Google Patents

コリン作動薬および迷走神経刺激による炎症性サイトカイン産生の阻害 Download PDF

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JP2004510695A
JP2004510695A JP2001585770A JP2001585770A JP2004510695A JP 2004510695 A JP2004510695 A JP 2004510695A JP 2001585770 A JP2001585770 A JP 2001585770A JP 2001585770 A JP2001585770 A JP 2001585770A JP 2004510695 A JP2004510695 A JP 2004510695A
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disease
inflammatory cytokine
syndrome
stimulated
sepsis
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JP2004510695A5 (https=
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トレイシー、ケヴィン・ジェイ
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Feinstein Institutes for Medical Research
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North Shore Long Island Jewish Research Institute
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
JP2001585770A 2000-05-23 2001-05-16 コリン作動薬および迷走神経刺激による炎症性サイトカイン産生の阻害 Pending JP2004510695A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20636400P 2000-05-23 2000-05-23
US09/855,446 US6610713B2 (en) 2000-05-23 2001-05-15 Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
PCT/US2001/015708 WO2001089526A1 (en) 2000-05-23 2001-05-16 Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation

Publications (2)

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JP2004510695A true JP2004510695A (ja) 2004-04-08
JP2004510695A5 JP2004510695A5 (https=) 2008-07-10

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JP2001585770A Pending JP2004510695A (ja) 2000-05-23 2001-05-16 コリン作動薬および迷走神経刺激による炎症性サイトカイン産生の阻害

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US (2) US6610713B2 (https=)
EP (1) EP1307196A4 (https=)
JP (1) JP2004510695A (https=)
AU (2) AU6162901A (https=)
CA (1) CA2408791C (https=)
WO (1) WO2001089526A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
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WO2007040128A1 (ja) * 2005-09-30 2007-04-12 Masaru Sugimachi 心不全治療薬
JP2009536193A (ja) * 2006-05-08 2009-10-08 ヘレラ，アルツロ ソリス 予防若しくは治療の形態で投与されるα−ＭＳＨを用いた、改善の余地のある多様な病理学的過程に関する治療におけるニコチン、そのアナログ、その前駆体またはその誘導体の使用
US8071098B2 (en) 2006-05-19 2011-12-06 National University Corporation Okayama University Method of preventing cerebral vasospasm with anti-HMGB1 antibody

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