JP2004509871A5 - - Google Patents
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- Publication number
- JP2004509871A5 JP2004509871A5 JP2002529071A JP2002529071A JP2004509871A5 JP 2004509871 A5 JP2004509871 A5 JP 2004509871A5 JP 2002529071 A JP2002529071 A JP 2002529071A JP 2002529071 A JP2002529071 A JP 2002529071A JP 2004509871 A5 JP2004509871 A5 JP 2004509871A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- embedded image
- allergy
- disorders
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000001875 compounds Chemical class 0.000 description 39
- 206010020751 Hypersensitivity Diseases 0.000 description 10
- 125000000217 alkyl group Chemical group 0.000 description 10
- 230000007815 allergy Effects 0.000 description 10
- 208000026935 allergic disease Diseases 0.000 description 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 8
- 239000008194 pharmaceutical composition Substances 0.000 description 6
- 208000024172 Cardiovascular disease Diseases 0.000 description 5
- 206010061218 Inflammation Diseases 0.000 description 5
- 206010028735 Nasal congestion Diseases 0.000 description 5
- 208000008589 Obesity Diseases 0.000 description 5
- 230000008369 airway response Effects 0.000 description 5
- 210000003169 central nervous system Anatomy 0.000 description 5
- 201000010099 disease Diseases 0.000 description 5
- 210000001035 gastrointestinal tract Anatomy 0.000 description 5
- 230000004054 inflammatory process Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 235000020824 obesity Nutrition 0.000 description 5
- 125000004432 carbon atom Chemical group C* 0.000 description 4
- 229910052739 hydrogen Inorganic materials 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 229910052757 nitrogen Inorganic materials 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 4
- 239000012453 solvate Substances 0.000 description 4
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 description 3
- 208000035475 disorder Diseases 0.000 description 3
- 239000003937 drug carrier Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000001257 hydrogen Substances 0.000 description 3
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 3
- 208000026344 Nasal disease Diseases 0.000 description 2
- 208000030880 Nose disease Diseases 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 125000003545 alkoxy group Chemical group 0.000 description 2
- 229910052736 halogen Inorganic materials 0.000 description 2
- 150000002367 halogens Chemical class 0.000 description 2
- 239000000938 histamine H1 antagonist Substances 0.000 description 2
- 239000003395 histamine H3 receptor antagonist Substances 0.000 description 2
- 150000001204 N-oxides Chemical class 0.000 description 1
- 206010039085 Rhinitis allergic Diseases 0.000 description 1
- 201000010105 allergic rhinitis Diseases 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- -1 enantiomers Chemical class 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23405300P | 2000-09-20 | 2000-09-20 | |
| PCT/US2001/029095 WO2002024659A2 (en) | 2000-09-20 | 2001-09-18 | Substituted imidazoles as dual histamine h1 and h3 agonists or antgonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004509871A JP2004509871A (ja) | 2004-04-02 |
| JP2004509871A5 true JP2004509871A5 (enExample) | 2008-09-11 |
Family
ID=22879692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002529071A Withdrawn JP2004509871A (ja) | 2000-09-20 | 2001-09-18 | 二重ヒスタミンｈ１およびｈ３のアゴニストまたはアンタゴニストとしての置換イミダゾール |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6506756B2 (enExample) |
| EP (1) | EP1318994B1 (enExample) |
| JP (1) | JP2004509871A (enExample) |
| CN (1) | CN1461303A (enExample) |
| AR (1) | AR030946A1 (enExample) |
| AT (1) | ATE387439T1 (enExample) |
| AU (1) | AU2001292730A1 (enExample) |
| CA (1) | CA2421826C (enExample) |
| DE (1) | DE60133014T2 (enExample) |
| ES (1) | ES2300364T3 (enExample) |
| HK (1) | HK1052179A1 (enExample) |
| MX (1) | MXPA03002448A (enExample) |
| MY (1) | MY117975A (enExample) |
| TW (1) | TW589303B (enExample) |
| WO (1) | WO2002024659A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6607862B2 (en) | 2001-08-24 | 2003-08-19 | Intel Corporation | Damascene extreme ultraviolet lithography alternative phase shift photomask and method of making |
| US7105505B2 (en) | 2002-04-18 | 2006-09-12 | Schering Corporation | Benzimidazole derivatives useful as histamine H3 antagonists |
| EP1499316B1 (en) * | 2002-04-18 | 2008-03-19 | Schering Corporation | (1-4-piperidinyl)benzimidazole derivatives useful as histamine h3 antagonists |
| WO2003103669A1 (en) * | 2002-04-18 | 2003-12-18 | Schering Corporation | 1-(4-piperidinyl) benzimidazolones as histamine h3 antagonists |
| NL1026634C2 (nl) * | 2004-07-12 | 2006-01-16 | Willem Jacob Van Der Burg | Psychofarmaceutisch preparaat en werkzame stof daarin. |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
| US9224955B1 (en) * | 2014-10-31 | 2015-12-29 | Feng-wen Yen | Purifying method for organic optoelectronic material |
| CN113880808B (zh) * | 2020-07-03 | 2024-12-31 | 合肥医工医药股份有限公司 | 一类三唑类化合物、制备方法及其医药用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2586562B1 (fr) | 1985-09-02 | 1989-03-10 | Inst Nat Sante Rech Med | Composition pharmaceutique contenant de l'a-methylhistamine |
| ZA893104B (en) * | 1988-04-28 | 1989-12-27 | Schering Corp | Novel benzopyrido piperidine,piperidylidene and piperazine compounds,compositions,methods of manufacture and methods of use |
| GB8916947D0 (en) | 1989-07-25 | 1989-09-13 | Smith Kline French Lab | Medicaments |
| DK0448765T3 (da) | 1990-03-30 | 1994-09-19 | Heumann Pharma Gmbh & Co | Anvendelse af guanidinderivater til fremstilling af et lægemiddel med NPY-antagonistisk virkning |
| GB9115740D0 (en) | 1991-07-20 | 1991-09-04 | Smithkline Beecham Plc | Medicaments |
| WO1993012093A1 (en) | 1991-12-18 | 1993-06-24 | Schering Corporation | Imidazolyl-alkyl-piperazine and -diazepine derivatives as histamine h3 agonists/antagonists |
| US5352707A (en) | 1992-03-26 | 1994-10-04 | Harbor Branch Oceanographic Institution, Inc. | Method for treating airway congestion |
| NZ330898A (en) | 1993-11-15 | 2000-01-28 | Schering Corp | Phenyl-alkyl imidazoles as H3-receptor antagonists in particular for the treatment of inflammation |
| FR2732017B1 (fr) | 1995-03-21 | 2000-09-22 | Inst Nat Sante Rech Med | Nouveaux derives de l'imidazole antagonistes et/ou agonistes du recepteur h3 de l'histamine, leur preparation et leurs applications therapeutiques |
| PT1019050E (pt) | 1997-06-24 | 2002-09-30 | Novo Nordisk As | Utilizacao de agonisticos e de antagonisticos de somatostatina para o tratamento de doencas associadas ao olho |
| US5869479A (en) | 1997-08-14 | 1999-02-09 | Schering Corporation | Treatment of upper airway allergic responses |
| AU4387699A (en) | 1998-07-24 | 2000-02-14 | Russinsky Limited | A process for preparing benzocycloheptapyridin-11-ones |
-
2001
- 2001-09-18 MY MYPI20014365A patent/MY117975A/en unknown
- 2001-09-18 AT AT01973119T patent/ATE387439T1/de not_active IP Right Cessation
- 2001-09-18 AR ARP010104399A patent/AR030946A1/es unknown
- 2001-09-18 DE DE60133014T patent/DE60133014T2/de not_active Expired - Lifetime
- 2001-09-18 CN CN01815978A patent/CN1461303A/zh active Pending
- 2001-09-18 EP EP01973119A patent/EP1318994B1/en not_active Expired - Lifetime
- 2001-09-18 JP JP2002529071A patent/JP2004509871A/ja not_active Withdrawn
- 2001-09-18 AU AU2001292730A patent/AU2001292730A1/en not_active Abandoned
- 2001-09-18 ES ES01973119T patent/ES2300364T3/es not_active Expired - Lifetime
- 2001-09-18 US US09/954,867 patent/US6506756B2/en not_active Expired - Fee Related
- 2001-09-18 HK HK03104436.1A patent/HK1052179A1/zh unknown
- 2001-09-18 WO PCT/US2001/029095 patent/WO2002024659A2/en not_active Ceased
- 2001-09-18 CA CA002421826A patent/CA2421826C/en not_active Expired - Fee Related
- 2001-09-18 MX MXPA03002448A patent/MXPA03002448A/es active IP Right Grant
- 2001-09-19 TW TW090123001A patent/TW589303B/zh not_active IP Right Cessation
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