JP2004509645A5 - - Google Patents
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- Publication number
- JP2004509645A5 JP2004509645A5 JP2002530855A JP2002530855A JP2004509645A5 JP 2004509645 A5 JP2004509645 A5 JP 2004509645A5 JP 2002530855 A JP2002530855 A JP 2002530855A JP 2002530855 A JP2002530855 A JP 2002530855A JP 2004509645 A5 JP2004509645 A5 JP 2004509645A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- array
- proteins
- nuclease
- tag
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 description 35
- 102000004169 proteins and genes Human genes 0.000 description 32
- 108090000623 proteins and genes Proteins 0.000 description 32
- 108020004414 DNA Proteins 0.000 description 9
- 239000003550 marker Substances 0.000 description 8
- 101710163270 Nuclease Proteins 0.000 description 6
- 238000003498 protein array Methods 0.000 description 6
- 238000012216 screening Methods 0.000 description 6
- 102000053602 DNA Human genes 0.000 description 5
- 108700026244 Open Reading Frames Proteins 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 3
- 108010037497 3'-nucleotidase Proteins 0.000 description 2
- 108020004705 Codon Proteins 0.000 description 2
- 108010017826 DNA Polymerase I Proteins 0.000 description 2
- 102000004594 DNA Polymerase I Human genes 0.000 description 2
- 108091026898 Leader sequence (mRNA) Proteins 0.000 description 2
- 108091036066 Three prime untranslated region Proteins 0.000 description 2
- 230000003321 amplification Effects 0.000 description 2
- 238000012217 deletion Methods 0.000 description 2
- 230000037430 deletion Effects 0.000 description 2
- 238000003199 nucleic acid amplification method Methods 0.000 description 2
- 108010001857 Cell Surface Receptors Proteins 0.000 description 1
- 108091026890 Coding region Proteins 0.000 description 1
- 108060002716 Exonuclease Proteins 0.000 description 1
- 108010043121 Green Fluorescent Proteins Proteins 0.000 description 1
- 102000004144 Green Fluorescent Proteins Human genes 0.000 description 1
- 108010093488 His-His-His-His-His-His Proteins 0.000 description 1
- 101710175625 Maltose/maltodextrin-binding periplasmic protein Proteins 0.000 description 1
- 108010086093 Mung Bean Nuclease Proteins 0.000 description 1
- 108020004711 Nucleic Acid Probes Proteins 0.000 description 1
- 108010006785 Taq Polymerase Proteins 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 238000010367 cloning Methods 0.000 description 1
- 239000002299 complementary DNA Substances 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 108010052305 exodeoxyribonuclease III Proteins 0.000 description 1
- 102000013165 exonuclease Human genes 0.000 description 1
- 239000013604 expression vector Substances 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 239000005090 green fluorescent protein Substances 0.000 description 1
- 230000003100 immobilizing effect Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 102000006240 membrane receptors Human genes 0.000 description 1
- 108020004999 messenger RNA Proteins 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002853 nucleic acid probe Substances 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000001915 proofreading effect Effects 0.000 description 1
- 108020001580 protein domains Proteins 0.000 description 1
- 230000006916 protein interaction Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 238000010839 reverse transcription Methods 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0020357A GB0020357D0 (en) | 2000-08-17 | 2000-08-17 | Method |
| US24799500P | 2000-11-14 | 2000-11-14 | |
| PCT/GB2001/003693 WO2002027327A2 (en) | 2000-08-17 | 2001-08-17 | Rapid profiling of the interactions between a chemical entity and proteins in a given proteome |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004509645A JP2004509645A (ja) | 2004-04-02 |
| JP2004509645A5 true JP2004509645A5 (enExample) | 2008-10-02 |
Family
ID=26244855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002530855A Pending JP2004509645A (ja) | 2000-08-17 | 2001-08-17 | 方法 |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1326970A2 (enExample) |
| JP (1) | JP2004509645A (enExample) |
| KR (1) | KR20030043933A (enExample) |
| CN (1) | CN1494589A (enExample) |
| AU (1) | AU2001279948A1 (enExample) |
| BR (1) | BR0113330A (enExample) |
| CA (1) | CA2420415A1 (enExample) |
| GB (1) | GB2384779B (enExample) |
| IL (1) | IL154486A0 (enExample) |
| WO (1) | WO2002027327A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0202018D0 (en) | 2002-01-29 | 2002-03-13 | Sense Proteomic Ltd | Tag and method |
| DE60315343T2 (de) * | 2002-10-25 | 2008-04-17 | Sense Proteomic Ltd., Maidenhead | Neuartige verwendungen von durch ble-gene kodierten proteinen und antibiotika aus der bleomycin-familie |
| US20060094059A1 (en) * | 2004-09-22 | 2006-05-04 | Odyssey Thera, Inc. | Methods for identifying new drug leads and new therapeutic uses for known drugs |
| GB2460717A (en) | 2008-06-11 | 2009-12-16 | Sense Proteomic Ltd | Autoantibodies for the detection of a predisposition to Lupus |
| GB2478734A (en) | 2010-03-15 | 2011-09-21 | Sense Proteomic Ltd | Auto-antibody biomarkers of prostate cancer |
| GB201017520D0 (en) | 2010-10-15 | 2010-12-01 | Sense Proteomic Ltd | Biomarkers |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1003853B1 (en) * | 1997-09-03 | 2005-11-30 | Biovation Limited | Methods for protein screening |
| WO1999039210A1 (en) * | 1998-01-29 | 1999-08-05 | Miller, Samuel | High density arrays for proteome analysis and methods and compositions therefor |
| CA2323638A1 (en) * | 1998-04-03 | 1999-10-14 | Phylos, Inc. | Addressable protein arrays |
| US6406921B1 (en) * | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
| ATE343132T1 (de) * | 1998-08-12 | 2006-11-15 | Zycos Inc | Darstellung des profils und katalogisierung von exprimierten proteinmarkern |
| AU778194B2 (en) * | 1999-07-12 | 2004-11-18 | Bristol-Myers Squibb Company | C-terminal protein tagging |
| CA2369742A1 (en) * | 2000-01-31 | 2001-08-09 | Sense Proteomic Limited | Methods of generating protein expression arrays and the use thereof in rapid screening |
-
2001
- 2001-08-17 EP EP01958221A patent/EP1326970A2/en not_active Withdrawn
- 2001-08-17 BR BR0113330-6A patent/BR0113330A/pt not_active IP Right Cessation
- 2001-08-17 KR KR10-2003-7002339A patent/KR20030043933A/ko not_active Withdrawn
- 2001-08-17 JP JP2002530855A patent/JP2004509645A/ja active Pending
- 2001-08-17 AU AU2001279948A patent/AU2001279948A1/en not_active Abandoned
- 2001-08-17 IL IL15448601A patent/IL154486A0/xx unknown
- 2001-08-17 CN CNA018157068A patent/CN1494589A/zh active Pending
- 2001-08-17 WO PCT/GB2001/003693 patent/WO2002027327A2/en not_active Ceased
- 2001-08-17 CA CA002420415A patent/CA2420415A1/en not_active Abandoned
- 2001-08-17 GB GB0306057A patent/GB2384779B/en not_active Expired - Fee Related
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