CA2420415A1 - Rapid profiling of the interactions between a chemical entity and proteins in a given proteome - Google Patents

Rapid profiling of the interactions between a chemical entity and proteins in a given proteome Download PDF

Info

Publication number
CA2420415A1
CA2420415A1 CA002420415A CA2420415A CA2420415A1 CA 2420415 A1 CA2420415 A1 CA 2420415A1 CA 002420415 A CA002420415 A CA 002420415A CA 2420415 A CA2420415 A CA 2420415A CA 2420415 A1 CA2420415 A1 CA 2420415A1
Authority
CA
Canada
Prior art keywords
proteins
protein
array
dna
tagged
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002420415A
Other languages
English (en)
French (fr)
Inventor
Jonathan Michael Blackburn
Michelle Anne Mulder
Mitali Samaddar
Roland Kozlowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sense Proteomic Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0020357A external-priority patent/GB0020357D0/en
Application filed by Individual filed Critical Individual
Publication of CA2420415A1 publication Critical patent/CA2420415A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00Methods of screening libraries
    • C40B30/04Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845Methods of identifying protein-protein interactions in protein mixtures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
CA002420415A 2000-08-17 2001-08-17 Rapid profiling of the interactions between a chemical entity and proteins in a given proteome Abandoned CA2420415A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0020357A GB0020357D0 (en) 2000-08-17 2000-08-17 Method
GB0020357.0 2000-08-17
US24799500P 2000-11-14 2000-11-14
US60/247,995 2000-11-14
PCT/GB2001/003693 WO2002027327A2 (en) 2000-08-17 2001-08-17 Rapid profiling of the interactions between a chemical entity and proteins in a given proteome

Publications (1)

Publication Number Publication Date
CA2420415A1 true CA2420415A1 (en) 2002-04-04

Family

ID=26244855

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002420415A Abandoned CA2420415A1 (en) 2000-08-17 2001-08-17 Rapid profiling of the interactions between a chemical entity and proteins in a given proteome

Country Status (10)

Country Link
EP (1) EP1326970A2 (enExample)
JP (1) JP2004509645A (enExample)
KR (1) KR20030043933A (enExample)
CN (1) CN1494589A (enExample)
AU (1) AU2001279948A1 (enExample)
BR (1) BR0113330A (enExample)
CA (1) CA2420415A1 (enExample)
GB (1) GB2384779B (enExample)
IL (1) IL154486A0 (enExample)
WO (1) WO2002027327A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0202018D0 (en) 2002-01-29 2002-03-13 Sense Proteomic Ltd Tag and method
JP2006506447A (ja) * 2002-10-25 2006-02-23 センス プロテオミック リミテッド Ble遺伝子によってコードされているタンパク質、及びブレオマイシン・ファミリー由来抗生物質の新規使用方法
US20060094059A1 (en) * 2004-09-22 2006-05-04 Odyssey Thera, Inc. Methods for identifying new drug leads and new therapeutic uses for known drugs
GB2460717A (en) 2008-06-11 2009-12-16 Sense Proteomic Ltd Autoantibodies for the detection of a predisposition to Lupus
GB2478734A (en) 2010-03-15 2011-09-21 Sense Proteomic Ltd Auto-antibody biomarkers of prostate cancer
GB201017520D0 (en) 2010-10-15 2010-12-01 Sense Proteomic Ltd Biomarkers

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999011777A1 (en) * 1997-09-03 1999-03-11 Biovation Limited Methods for protein screening
EP1051624A4 (en) * 1998-01-29 2002-05-02 Glaucus Proteomics B V HIGH DENSITY MATERIALS FOR PROTEOM ANALYSIS AND METHOD AND COMPOSITIONS THEREFOR
JP2002510505A (ja) * 1998-04-03 2002-04-09 フィロス インク. 位置特定可能な蛋白質アレイ
US6406921B1 (en) * 1998-07-14 2002-06-18 Zyomyx, Incorporated Protein arrays for high-throughput screening
WO2000009654A2 (en) * 1998-08-12 2000-02-24 Zycos Inc. Profiling and cataloging expressed protein tags
IL146451A0 (en) * 1999-07-12 2002-07-25 Phylos Inc C-terminal protein tagging
EP1203238B1 (en) * 2000-01-31 2010-08-11 Sense Proteomic Limited Methods of generating protein expression arrays and the use thereof in rapid screening

Also Published As

Publication number Publication date
KR20030043933A (ko) 2003-06-02
JP2004509645A (ja) 2004-04-02
IL154486A0 (en) 2003-09-17
CN1494589A (zh) 2004-05-05
WO2002027327A3 (en) 2003-04-17
GB2384779B (en) 2004-09-29
WO2002027327A2 (en) 2002-04-04
EP1326970A2 (en) 2003-07-16
GB0306057D0 (en) 2003-04-23
AU2001279948A1 (en) 2002-04-08
GB2384779A (en) 2003-08-06
BR0113330A (pt) 2003-12-30

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Legal Events

Date Code Title Description
FZDE Discontinued