WO2002027327A3 - Rapid profiling of the interactions between a chemical entity and proteins in a given proteome - Google Patents
Rapid profiling of the interactions between a chemical entity and proteins in a given proteome Download PDFInfo
- Publication number
- WO2002027327A3 WO2002027327A3 PCT/GB2001/003693 GB0103693W WO0227327A3 WO 2002027327 A3 WO2002027327 A3 WO 2002027327A3 GB 0103693 W GB0103693 W GB 0103693W WO 0227327 A3 WO0227327 A3 WO 0227327A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- proteins
- interactions
- chemical entity
- rapid profiling
- given proteome
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Abstract
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002420415A CA2420415A1 (en) | 2000-08-17 | 2001-08-17 | Rapid profiling of the interactions between a chemical entity and proteins in a given proteome |
EP01958221A EP1326970A2 (en) | 2000-08-17 | 2001-08-17 | Rapid profiling of the interactions between a chemical entity and proteins in a given proteome |
KR10-2003-7002339A KR20030043933A (en) | 2000-08-17 | 2001-08-17 | Method |
GB0306057A GB2384779B (en) | 2000-08-17 | 2001-08-17 | Method for the production of tagged proteins |
IL15448601A IL154486A0 (en) | 2000-08-17 | 2001-08-17 | Method |
BR0113330-6A BR0113330A (en) | 2000-08-17 | 2001-08-17 | Method for producing one or more proteins, library of labeled proteins, method for producing a protein array, arrangement, methods for screening one or more compounds for biological activity, one or more proteins for protein-protein interactions and specific nucleic acid protein, use of an array, methods of generating an antibody array, and screening for abundance or function of proteins, and use of a labeled protein |
AU2001279948A AU2001279948A1 (en) | 2000-08-17 | 2001-08-17 | Rapid profiling of the interactions between a chemical entity and proteins in a given proteome |
JP2002530855A JP2004509645A (en) | 2000-08-17 | 2001-08-17 | Method |
US10/114,334 US7094568B2 (en) | 2000-08-17 | 2002-04-03 | Method for producing proteins tagged at the N- or C-terminus |
US11/237,597 US20060024791A1 (en) | 2000-08-17 | 2005-09-27 | Method |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0020357A GB0020357D0 (en) | 2000-08-17 | 2000-08-17 | Method |
GB0020357.0 | 2000-08-17 | ||
US24799500P | 2000-11-14 | 2000-11-14 | |
US60/247,995 | 2000-11-14 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/114,334 Continuation-In-Part US7094568B2 (en) | 2000-08-17 | 2002-04-03 | Method for producing proteins tagged at the N- or C-terminus |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002027327A2 WO2002027327A2 (en) | 2002-04-04 |
WO2002027327A3 true WO2002027327A3 (en) | 2003-04-17 |
Family
ID=26244855
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2001/003693 WO2002027327A2 (en) | 2000-08-17 | 2001-08-17 | Rapid profiling of the interactions between a chemical entity and proteins in a given proteome |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1326970A2 (en) |
JP (1) | JP2004509645A (en) |
KR (1) | KR20030043933A (en) |
CN (1) | CN1494589A (en) |
AU (1) | AU2001279948A1 (en) |
BR (1) | BR0113330A (en) |
CA (1) | CA2420415A1 (en) |
GB (1) | GB2384779B (en) |
IL (1) | IL154486A0 (en) |
WO (1) | WO2002027327A2 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0202018D0 (en) | 2002-01-29 | 2002-03-13 | Sense Proteomic Ltd | Tag and method |
AU2003302133A1 (en) * | 2002-10-25 | 2004-06-15 | Sense Proteomic Limited | Uses of ble proteins and antibiotics from the bleomycin family |
US20060094059A1 (en) * | 2004-09-22 | 2006-05-04 | Odyssey Thera, Inc. | Methods for identifying new drug leads and new therapeutic uses for known drugs |
GB2460717A (en) | 2008-06-11 | 2009-12-16 | Sense Proteomic Ltd | Autoantibodies for the detection of a predisposition to Lupus |
GB2478734A (en) | 2010-03-15 | 2011-09-21 | Sense Proteomic Ltd | Auto-antibody biomarkers of prostate cancer |
GB201017520D0 (en) | 2010-10-15 | 2010-12-01 | Sense Proteomic Ltd | Biomarkers |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999011777A1 (en) * | 1997-09-03 | 1999-03-11 | Biovation Limited | Methods for protein screening |
WO1999039210A1 (en) * | 1998-01-29 | 1999-08-05 | Miller, Samuel | High density arrays for proteome analysis and methods and compositions therefor |
WO1999051773A1 (en) * | 1998-04-03 | 1999-10-14 | Phylos, Inc. | Addressable protein arrays |
WO2000004382A1 (en) * | 1998-07-14 | 2000-01-27 | Zyomyx, Inc. | Arrays of proteins and methods of use thereof |
WO2000009654A2 (en) * | 1998-08-12 | 2000-02-24 | Zycos Inc. | Profiling and cataloging expressed protein tags |
WO2001004265A2 (en) * | 1999-07-12 | 2001-01-18 | Phylos, Inc. | C-terminal protein tagging |
WO2001057198A2 (en) * | 2000-01-31 | 2001-08-09 | Sense Proteomic Limited | Methods of generating protein expression arrays and the use thereof in rapid screening |
-
2001
- 2001-08-17 KR KR10-2003-7002339A patent/KR20030043933A/en not_active Application Discontinuation
- 2001-08-17 JP JP2002530855A patent/JP2004509645A/en active Pending
- 2001-08-17 WO PCT/GB2001/003693 patent/WO2002027327A2/en active Application Filing
- 2001-08-17 EP EP01958221A patent/EP1326970A2/en not_active Withdrawn
- 2001-08-17 IL IL15448601A patent/IL154486A0/en unknown
- 2001-08-17 AU AU2001279948A patent/AU2001279948A1/en not_active Abandoned
- 2001-08-17 BR BR0113330-6A patent/BR0113330A/en not_active IP Right Cessation
- 2001-08-17 CN CNA018157068A patent/CN1494589A/en active Pending
- 2001-08-17 GB GB0306057A patent/GB2384779B/en not_active Expired - Fee Related
- 2001-08-17 CA CA002420415A patent/CA2420415A1/en not_active Abandoned
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999011777A1 (en) * | 1997-09-03 | 1999-03-11 | Biovation Limited | Methods for protein screening |
WO1999039210A1 (en) * | 1998-01-29 | 1999-08-05 | Miller, Samuel | High density arrays for proteome analysis and methods and compositions therefor |
WO1999051773A1 (en) * | 1998-04-03 | 1999-10-14 | Phylos, Inc. | Addressable protein arrays |
WO2000004382A1 (en) * | 1998-07-14 | 2000-01-27 | Zyomyx, Inc. | Arrays of proteins and methods of use thereof |
WO2000009654A2 (en) * | 1998-08-12 | 2000-02-24 | Zycos Inc. | Profiling and cataloging expressed protein tags |
WO2001004265A2 (en) * | 1999-07-12 | 2001-01-18 | Phylos, Inc. | C-terminal protein tagging |
WO2001057198A2 (en) * | 2000-01-31 | 2001-08-09 | Sense Proteomic Limited | Methods of generating protein expression arrays and the use thereof in rapid screening |
Non-Patent Citations (3)
Title |
---|
PANDEY AKHILESH ET AL: "Proteomics to study genes and genomes", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 405, no. 6788, 15 June 2000 (2000-06-15), pages 837 - 846, XP002172041, ISSN: 0028-0836 * |
ROBERT L STRAUSBERG AND M J FINLEY AUSTIN: "Functional genomics: technological challenges and opportunities", PHYSIOLOGICAL GENOMICS, AMERICAN PHYSIOLOGICAL SOCIETY, BETHESDA, MD, US, vol. 1, no. 1, 15 July 1999 (1999-07-15), pages 25 - 32, XP002172042, ISSN: 1094-8341 * |
SPEIGHT R E ET AL: "A new plasmid display technology for the in vitro selection of functional phenotype-genotype linked proteins.", CHEMISTRY & BIOLOGY. ENGLAND OCT 2001, vol. 8, no. 10, October 2001 (2001-10-01), pages 951 - 965, XP002217504, ISSN: 1074-5521 * |
Also Published As
Publication number | Publication date |
---|---|
BR0113330A (en) | 2003-12-30 |
JP2004509645A (en) | 2004-04-02 |
GB2384779A (en) | 2003-08-06 |
CA2420415A1 (en) | 2002-04-04 |
KR20030043933A (en) | 2003-06-02 |
IL154486A0 (en) | 2003-09-17 |
WO2002027327A2 (en) | 2002-04-04 |
EP1326970A2 (en) | 2003-07-16 |
CN1494589A (en) | 2004-05-05 |
GB0306057D0 (en) | 2003-04-23 |
GB2384779B (en) | 2004-09-29 |
AU2001279948A1 (en) | 2002-04-08 |
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