JP2004504036A - 蛍光プローブを使用することによる標的細胞の直接的な遺伝分析のための方法 - Google Patents

蛍光プローブを使用することによる標的細胞の直接的な遺伝分析のための方法 Download PDF

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JP2004504036A
JP2004504036A JP2002512414A JP2002512414A JP2004504036A JP 2004504036 A JP2004504036 A JP 2004504036A JP 2002512414 A JP2002512414 A JP 2002512414A JP 2002512414 A JP2002512414 A JP 2002512414A JP 2004504036 A JP2004504036 A JP 2004504036A
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cells
cell
sequence
target
fetal
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JP2004504036A5 (enExample
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ハイコ　ヴィーブッシュ
トーマス　シュミット−ヨーン
ユルゲン　ヴァイトナー
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プレナディア　ゲゼルシャフト　ミット　ベシュレンクテル　ハフツング
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Publication of JP2004504036A publication Critical patent/JP2004504036A/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
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  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2002512414A 2000-07-14 2001-07-16 蛍光プローブを使用することによる標的細胞の直接的な遺伝分析のための方法 Pending JP2004504036A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00115268A EP1172445A1 (en) 2000-07-14 2000-07-14 A method for direct genetic analysis of target cells by using fluorescence probes
PCT/EP2001/008202 WO2002006524A2 (en) 2000-07-14 2001-07-16 A method for direct genetic analysis of target cells by using flourescence probes

Publications (2)

Publication Number Publication Date
JP2004504036A true JP2004504036A (ja) 2004-02-12
JP2004504036A5 JP2004504036A5 (enExample) 2005-02-24

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JP2002512414A Pending JP2004504036A (ja) 2000-07-14 2001-07-16 蛍光プローブを使用することによる標的細胞の直接的な遺伝分析のための方法

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US (1) US20040091880A1 (enExample)
EP (1) EP1172445A1 (enExample)
JP (1) JP2004504036A (enExample)
AU (1) AU2001289664A1 (enExample)
CA (1) CA2415731A1 (enExample)
IL (1) IL153906A0 (enExample)
NO (1) NO20030158L (enExample)
WO (1) WO2002006524A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010010951A1 (ja) * 2008-07-24 2010-01-28 Kuroda Masahiko 子宮内膜症関連疾患の指標ｍＲＮＡの発現の検出方法およびそれに用いるプローブ
JP2014517324A (ja) * 2011-06-17 2014-07-17 コンスティテューション・メディカル・インコーポレイテッド 生体試料の組織処理のための溶液

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DE10133308A1 (de) * 2001-07-12 2003-01-23 Praenadia Gmbh Verfahren zum Nachweis einer Nukleinsäure
AU2008202162B2 (en) * 2002-08-28 2011-04-07 Chromocell Corporation Selection and Isolation of Living Cells Using mRNA-Binding Probes
US20040226556A1 (en) 2003-05-13 2004-11-18 Deem Mark E. Apparatus for treating asthma using neurotoxin
ES2379634T3 (es) 2004-02-18 2012-04-30 Chromocell Corporation Métodos y materiales que usan sondas de señalización
CN101495650B (zh) 2005-06-20 2015-02-04 领先细胞医疗诊断有限公司 检测单个细胞中的核酸和鉴定异质大细胞群中罕见细胞的方法
US7655243B2 (en) * 2005-07-22 2010-02-02 The Foundry, Llc Methods and systems for toxin delivery to the nasal cavity
US10052465B2 (en) 2005-07-22 2018-08-21 The Foundry, Llc Methods and systems for toxin delivery to the nasal cavity
WO2007014003A2 (en) 2005-07-22 2007-02-01 The Foundry Inc. Systems and methods for delivery of a therapeutic agent
US12433837B2 (en) 2005-07-22 2025-10-07 The Foundry, Llc Systems and methods for delivery of a therapeutic agent
WO2007075929A2 (en) * 2005-12-23 2007-07-05 Alvitae Pharmaceuticals Methods and applications of molecular beacon imaging for identifying and validating genomic targets, and for drug screening
ITTO20070307A1 (it) * 2007-05-04 2008-11-05 Silicon Biosystems Spa Metodo e dispositivo per la diagnosi prenatale non-invasiva
US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
WO2009137819A1 (en) 2008-05-09 2009-11-12 Innovative Pulmonary Solutions, Inc. Systems, assemblies, and methods for treating a bronchial tree
JP2009072198A (ja) * 2008-10-24 2009-04-09 Chromocell Corp ｍＲＮＡ結合プローブを用いる生存細胞の選択および単離
US20110001963A1 (en) * 2009-07-02 2011-01-06 Durack Gary P System and method for the measurement of multiple emissions from multiple parallel flow channels in a flow cytometry system
US20130023433A1 (en) 2009-09-28 2013-01-24 Yuling Luo Methods of detecting nucleic acid sequences with high specificity
US9649153B2 (en) 2009-10-27 2017-05-16 Holaira, Inc. Delivery devices with coolable energy emitting assemblies
CA2780608C (en) 2009-11-11 2019-02-26 Innovative Pulmonary Solutions, Inc. Systems, apparatuses, and methods for treating tissue and controlling stenosis
US8911439B2 (en) 2009-11-11 2014-12-16 Holaira, Inc. Non-invasive and minimally invasive denervation methods and systems for performing the same
BR112012018166A2 (pt) 2010-01-21 2015-09-15 Biocep Ltd separação magnética de células raras.
ES2719502T3 (es) 2010-01-29 2019-07-10 Advanced Cell Diagnostics Inc Métodos de detección in situ de ácidos nucleicos
US8774488B2 (en) 2010-03-11 2014-07-08 Cellscape Corporation Method and device for identification of nucleated red blood cells from a maternal blood sample
WO2012178166A1 (en) * 2011-06-24 2012-12-27 Arryx, Inc. Method and apparatus for fractionating genetically distinct cells and cellular components
JP5753134B2 (ja) * 2012-07-20 2015-07-22 クロモセル コーポレイション ｍＲＮＡ結合プローブを用いる生存細胞の選択および単離
US9398933B2 (en) 2012-12-27 2016-07-26 Holaira, Inc. Methods for improving drug efficacy including a combination of drug administration and nerve modulation
US10240146B2 (en) 2014-07-30 2019-03-26 President And Fellows Of Harvard College Probe library construction
US20160177396A1 (en) * 2014-12-22 2016-06-23 Enzo Biochem, Inc. Comprehensive and comparative flow cytometry-based methods for identifying the state of a biological system
JP6716198B2 (ja) * 2015-03-27 2020-07-01 シスメックス株式会社 検体分析方法および検体分析装置
EP3913068B1 (en) 2015-10-12 2023-08-02 Advanced Cell Diagnostics, Inc. In situ detection of nucleotide variants in high noise samples, and compositions and methods related thereto
EP4386761A3 (en) * 2016-11-08 2024-09-04 President and Fellows of Harvard College Matrix imprinting and clearing
WO2018218150A1 (en) 2017-05-26 2018-11-29 President And Fellows Of Harvard College Systems and methods for high-throughput image-based screening
WO2020123742A1 (en) 2018-12-13 2020-06-18 President And Fellows Of Harvard College Amplification methods and systems for merfish and other applications
UA128273C2 (uk) 2019-06-07 2024-05-22 Арседі Байотек Апс Спосіб пренатальної діагностики (варанти)
CN114939450B (zh) * 2022-06-13 2023-10-10 广州金域医学检验中心有限公司 试管及试管防溢判读方法

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US5506098A (en) * 1991-09-04 1996-04-09 Daikin Industries, Ltd. In situ hybridization method
US5629147A (en) * 1992-07-17 1997-05-13 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
US5876978A (en) * 1993-04-06 1999-03-02 Medical College Of Ohio Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction
IL110364A0 (en) * 1993-07-19 1994-10-21 Aprogenex Inc Enriching and identifying fetal nucleated erythrocytes in maternal blood for in situ hybridization
US5925517A (en) * 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010010951A1 (ja) * 2008-07-24 2010-01-28 Kuroda Masahiko 子宮内膜症関連疾患の指標ｍＲＮＡの発現の検出方法およびそれに用いるプローブ
JP2014517324A (ja) * 2011-06-17 2014-07-17 コンスティテューション・メディカル・インコーポレイテッド 生体試料の組織処理のための溶液
US9677977B2 (en) 2011-06-17 2017-06-13 Roche Diagnostics Hematology, Inc. Fixative and staining solutions
US10656056B2 (en) 2011-06-17 2020-05-19 Roche Diagnostics Hematology, Inc. Fixative and staining solutions
US10914657B2 (en) 2011-06-17 2021-02-09 Roche Diagnostics Hematology, Inc. Fixative and staining solutions

Also Published As

Publication number Publication date
IL153906A0 (en) 2003-07-31
US20040091880A1 (en) 2004-05-13
NO20030158D0 (no) 2003-01-13
CA2415731A1 (en) 2002-01-24
WO2002006524A2 (en) 2002-01-24
AU2001289664A1 (en) 2002-01-30
EP1172445A1 (en) 2002-01-16
NO20030158L (no) 2003-03-10
WO2002006524A3 (en) 2002-06-27

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