JP2004501980A5 - - Google Patents
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- Publication number
- JP2004501980A5 JP2004501980A5 JP2002506761A JP2002506761A JP2004501980A5 JP 2004501980 A5 JP2004501980 A5 JP 2004501980A5 JP 2002506761 A JP2002506761 A JP 2002506761A JP 2002506761 A JP2002506761 A JP 2002506761A JP 2004501980 A5 JP2004501980 A5 JP 2004501980A5
- Authority
- JP
- Japan
- Prior art keywords
- pim
- immunogenic
- vaccine
- patient
- bovis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229960005486 vaccine Drugs 0.000 claims 22
- 239000013316 polymer of intrinsic microporosity Substances 0.000 claims 20
- 230000002163 immunogen Effects 0.000 claims 19
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 9
- 238000000034 method Methods 0.000 claims 8
- 230000001404 mediated effect Effects 0.000 claims 6
- 201000010099 disease Diseases 0.000 claims 5
- 230000028993 immune response Effects 0.000 claims 5
- 208000035475 disorder Diseases 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 150000004665 fatty acids Chemical group 0.000 claims 4
- 230000001939 inductive effect Effects 0.000 claims 4
- 241000186359 Mycobacterium Species 0.000 claims 3
- 230000000241 respiratory effect Effects 0.000 claims 3
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 claims 2
- 241000186366 Mycobacterium bovis Species 0.000 claims 2
- 239000013543 active substance Substances 0.000 claims 2
- 239000002671 adjuvant Substances 0.000 claims 2
- 208000006673 asthma Diseases 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims 2
- 229930195729 fatty acid Natural products 0.000 claims 2
- 239000000194 fatty acid Substances 0.000 claims 2
- 125000000311 mannosyl group Chemical group C1([C@@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 238000011282 treatment Methods 0.000 claims 2
- 206010061818 Disease progression Diseases 0.000 claims 1
- 206010014950 Eosinophilia Diseases 0.000 claims 1
- SQUHHTBVTRBESD-UHFFFAOYSA-N Hexa-Ac-myo-Inositol Natural products CC(=O)OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O SQUHHTBVTRBESD-UHFFFAOYSA-N 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 241001467552 Mycobacterium bovis BCG Species 0.000 claims 1
- 241000202934 Mycoplasma pneumoniae Species 0.000 claims 1
- 229960000190 bacillus calmette–guérin vaccine Drugs 0.000 claims 1
- 230000005750 disease progression Effects 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 claims 1
- 229960000367 inositol Drugs 0.000 claims 1
- 210000003928 nasal cavity Anatomy 0.000 claims 1
- 229920001542 oligosaccharide Polymers 0.000 claims 1
- 230000000069 prophylactic effect Effects 0.000 claims 1
- 238000011321 prophylaxis Methods 0.000 claims 1
- 210000002345 respiratory system Anatomy 0.000 claims 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ505538A NZ505538A (en) | 2000-07-03 | 2000-07-03 | A vaccine comprising immunogenic acyl glyceryl phosphatidylinositol manno-oligosaccharide (PIM); and the use of PIM for inducing an immune response in a patient effective in the prevention or treatment of Th2-mediated diseases or disorders such as asthma |
| PCT/NZ2001/000131 WO2002002140A1 (en) | 2000-07-03 | 2001-07-02 | Vaccine comprising active agent immunogenic acyl glyceryl phosphatidylinositol manno-oligosaccharide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004501980A JP2004501980A (ja) | 2004-01-22 |
| JP2004501980A5 true JP2004501980A5 (enExample) | 2005-02-24 |
Family
ID=19927977
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002506761A Pending JP2004501980A (ja) | 2000-07-03 | 2001-07-02 | 活性剤の免疫原性のアシル・グリセル・フォスファチジルイノシトール・マンノ−オリゴサッカライドを含んで成るワクチン |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20040022793A1 (enExample) |
| EP (1) | EP1301203A4 (enExample) |
| JP (1) | JP2004501980A (enExample) |
| CN (1) | CN1440295A (enExample) |
| AU (1) | AU2001280300A1 (enExample) |
| CA (1) | CA2414347A1 (enExample) |
| NZ (1) | NZ505538A (enExample) |
| WO (1) | WO2002002140A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004005532A2 (en) * | 2002-07-10 | 2004-01-15 | Massachusetts Institute Of Technology | Solid-phase and solution-phase synthesis of glycosylphosphatidylinositol glycans |
| WO2005049631A1 (en) * | 2003-11-18 | 2005-06-02 | The Malaghan Institute Of Medical Research | Synthetic molecules having immune activity |
| PL1800693T3 (pl) * | 2004-08-24 | 2013-12-31 | Chugai Pharmaceutical Co Ltd | Terapia adiuwantowa z zastosowaniem przeciwciała przeciw glipikanowi 3 |
| US20070087005A1 (en) | 2005-10-14 | 2007-04-19 | Lazar Gregory A | Anti-glypican-3 antibody |
| WO2007142510A1 (en) * | 2006-06-09 | 2007-12-13 | Erasmus University Medical Center Rotterdam | Modulation of the immune system by inositol phospholipids |
| EP2139501B1 (en) | 2007-03-21 | 2016-04-13 | National Research Council of Canada | Use of francisella tularensis for prevention and treatment of allergic airway disorders |
| CN102626386B (zh) * | 2012-04-28 | 2014-10-29 | 山东大学 | 一种卡介菌多糖核酸吸入气雾剂、制备方法及用途 |
| JP7096667B2 (ja) | 2015-07-01 | 2022-07-06 | 中外製薬株式会社 | Ｇｐｃ３標的治療剤が有効である患者に投与されるｇｐｃ３標的治療剤 |
| CN113663065B (zh) * | 2020-05-15 | 2024-01-16 | 山东大学 | 一种肌醇甘露寡糖缀合物、制备方法及作为抗结核糖疫苗的应用 |
| CN118178640B (zh) * | 2024-03-08 | 2025-11-21 | 中国农业大学 | 含有牛分枝杆菌表面多糖的佐剂及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS568320A (en) * | 1979-07-04 | 1981-01-28 | Chisato Maruyama | Drug for tumor immunotherapy comprising lipopolysaccharide as active constituent |
| FR2596651B1 (fr) * | 1986-04-08 | 1989-11-10 | Centre Nat Rech Scient | Nouveaux liposomes a base de phosphatidylinositolmannosides, et compositions pharmaceutiques les contenant |
| US5853737A (en) * | 1992-12-10 | 1998-12-29 | Brigham And Women's Hospital | Method for inducing a CD1-restricted immune response |
| US5679347A (en) * | 1992-12-10 | 1997-10-21 | Brigham And Women's Hospital | Methods of isolating CD1-presented antigens, vaccines comprising CD1-presented antigens, and cell lines for use in said methods |
| US6238676B1 (en) * | 1992-12-10 | 2001-05-29 | Brigham And Women's Hospital | Presentation of hydrophobic antigens to T-cells by CD1 molecules |
| GB2316323B (en) * | 1996-06-20 | 1999-09-22 | Aid Medic Ltd | Dispensing system |
| FR2792205B1 (fr) * | 1999-04-19 | 2001-07-27 | Inst Nat Sante Rech Med | Composition pharmaceutique comprenant des cellules nkt activees par des pim, et son utilisation en therapie |
-
2000
- 2000-07-03 NZ NZ505538A patent/NZ505538A/xx unknown
-
2001
- 2001-07-02 WO PCT/NZ2001/000131 patent/WO2002002140A1/en not_active Ceased
- 2001-07-02 AU AU2001280300A patent/AU2001280300A1/en not_active Abandoned
- 2001-07-02 JP JP2002506761A patent/JP2004501980A/ja active Pending
- 2001-07-02 CA CA002414347A patent/CA2414347A1/en not_active Abandoned
- 2001-07-02 CN CN01812245A patent/CN1440295A/zh active Pending
- 2001-07-02 EP EP01958675A patent/EP1301203A4/en not_active Withdrawn
- 2001-07-02 US US10/311,340 patent/US20040022793A1/en not_active Abandoned
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