JP2004501605A - Her−2に結合するアンタゴニスト - Google Patents
Her−2に結合するアンタゴニスト Download PDFInfo
- Publication number
- JP2004501605A JP2004501605A JP2001560693A JP2001560693A JP2004501605A JP 2004501605 A JP2004501605 A JP 2004501605A JP 2001560693 A JP2001560693 A JP 2001560693A JP 2001560693 A JP2001560693 A JP 2001560693A JP 2004501605 A JP2004501605 A JP 2004501605A
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence
- ecd
- amino acids
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/506,079 US7625859B1 (en) | 2000-02-16 | 2000-02-16 | HER-2 binding antagonists |
| PCT/US2001/005327 WO2001061356A1 (en) | 2000-02-16 | 2001-02-16 | Her-2 binding antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004501605A true JP2004501605A (ja) | 2004-01-22 |
| JP2004501605A5 JP2004501605A5 (https=) | 2006-06-22 |
Family
ID=24013084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001560693A Pending JP2004501605A (ja) | 2000-02-16 | 2001-02-16 | Her−2に結合するアンタゴニスト |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US7625859B1 (https=) |
| EP (1) | EP1257822B1 (https=) |
| JP (1) | JP2004501605A (https=) |
| AT (1) | ATE542138T1 (https=) |
| AU (1) | AU4157501A (https=) |
| CA (1) | CA2400473A1 (https=) |
| WO (1) | WO2001061356A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017518038A (ja) * | 2015-01-30 | 2017-07-06 | ジェノー バイオファーマ カンパニー リミテッド | 抗her2完全ヒト抗体の突然変異体抗体、及びそれをコードする遺伝子並びにそれらの使用 |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6541214B1 (en) | 1998-11-13 | 2003-04-01 | Oregon Heath Science University | N-terminally truncated HER-2/neu protein as a cancer prognostic indicator |
| US7396810B1 (en) * | 2000-08-14 | 2008-07-08 | Oregon Health Sciences University | Compositions and methods for treating cancer by modulating HER-2 and EGF receptors |
| US7393823B1 (en) | 1999-01-20 | 2008-07-01 | Oregon Health And Science University | HER-2 binding antagonists |
| US7625859B1 (en) | 2000-02-16 | 2009-12-01 | Oregon Health & Science University | HER-2 binding antagonists |
| AU779612C (en) | 1999-07-02 | 2005-12-15 | Genentech Inc. | Peptide compounds that bind HER2 |
| JP2006524035A (ja) * | 2002-12-26 | 2006-10-26 | シーマインズ リミテッド ライアビリティ カンパニー | 癌の診断、予後診断および治療のための方法および組成物 |
| EP1601684B1 (en) * | 2003-03-05 | 2014-10-15 | Dendreon Corporation | Alternative reading frame polypeptides for treatment |
| TWI472339B (zh) * | 2008-01-30 | 2015-02-11 | Genentech Inc | 包含結合至her2結構域ii之抗體及其酸性變異體的組合物 |
| NZ596468A (en) * | 2009-05-14 | 2013-11-29 | Nestec Sa | Biomarkers for determining sensitivity of breast cancer cells to her2-targeted therapy |
| US9427458B2 (en) | 2010-07-22 | 2016-08-30 | Consejo Nacional De Investigaciones Cientificas Y Tecnicas, Conicet | Methods for inhibiting cancer cell proliferation |
| KR101258144B1 (ko) | 2011-07-22 | 2013-04-30 | 한양대학교 산학협력단 | Ecm1 항체를 함유하는 항암용 조성물 |
| EP3303373B1 (en) | 2015-05-30 | 2020-04-08 | Molecular Templates, Inc. | De-immunized, shiga toxin a subunit scaffolds and cell-targeting molecules comprising the same |
| CN110612117B (zh) | 2018-04-17 | 2024-04-12 | 分子模板公司 | 包含去免疫化的志贺毒素a亚基支架的her2靶向分子 |
| WO2023168426A1 (en) | 2022-03-03 | 2023-09-07 | Enosi Therapeutics Corporation | Compositions and cells containing mixtures of oligo-trap fusion proteins (ofps) and uses thereof |
| WO2024186690A2 (en) | 2023-03-03 | 2024-09-12 | Enosi Therapeutics Corporation | Oligo-trap fusion proteins (ofps) and uses thereof |
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2011
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017518038A (ja) * | 2015-01-30 | 2017-07-06 | ジェノー バイオファーマ カンパニー リミテッド | 抗her2完全ヒト抗体の突然変異体抗体、及びそれをコードする遺伝子並びにそれらの使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20080219997A1 (en) | 2008-09-11 |
| US7935784B2 (en) | 2011-05-03 |
| ATE542138T1 (de) | 2012-02-15 |
| US7625859B1 (en) | 2009-12-01 |
| EP1257822B1 (en) | 2012-01-18 |
| AU4157501A (en) | 2001-08-27 |
| EP1257822A4 (en) | 2004-09-08 |
| WO2001061356A9 (en) | 2002-10-31 |
| US20100267027A1 (en) | 2010-10-21 |
| CA2400473A1 (en) | 2001-08-23 |
| WO2001061356A1 (en) | 2001-08-23 |
| EP1257822A1 (en) | 2002-11-20 |
| US20120045755A1 (en) | 2012-02-23 |
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