DK1510579T3 - Anvendelse af heregulin som en epitelcellevækstfaktor - Google Patents
Anvendelse af heregulin som en epitelcellevækstfaktorInfo
- Publication number
- DK1510579T3 DK1510579T3 DK04022325T DK04022325T DK1510579T3 DK 1510579 T3 DK1510579 T3 DK 1510579T3 DK 04022325 T DK04022325 T DK 04022325T DK 04022325 T DK04022325 T DK 04022325T DK 1510579 T3 DK1510579 T3 DK 1510579T3
- Authority
- DK
- Denmark
- Prior art keywords
- cell growth
- epithelial cell
- heregulin
- growth factor
- her3
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/4756—Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/40—Vectors comprising a peptide as targeting moiety, e.g. a synthetic peptide, from undefined source
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2059898A | 1998-02-04 | 1998-02-04 | |
PCT/US1999/002390 WO1999039729A2 (en) | 1998-02-04 | 1999-02-03 | Use of heregulin as an epithelial cell growth factor |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1510579T3 true DK1510579T3 (da) | 2009-11-30 |
Family
ID=21799510
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04022325T DK1510579T3 (da) | 1998-02-04 | 1999-02-03 | Anvendelse af heregulin som en epitelcellevækstfaktor |
Country Status (10)
Country | Link |
---|---|
US (1) | US20020042087A1 (da) |
EP (2) | EP1053009B1 (da) |
JP (1) | JP4485051B2 (da) |
AT (2) | ATE438720T1 (da) |
AU (1) | AU2581599A (da) |
CA (1) | CA2318857C (da) |
DE (2) | DE69941228D1 (da) |
DK (1) | DK1510579T3 (da) |
ES (2) | ES2229679T3 (da) |
WO (1) | WO1999039729A2 (da) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7396810B1 (en) | 2000-08-14 | 2008-07-08 | Oregon Health Sciences University | Compositions and methods for treating cancer by modulating HER-2 and EGF receptors |
US7393823B1 (en) | 1999-01-20 | 2008-07-01 | Oregon Health And Science University | HER-2 binding antagonists |
CA2373721C (en) | 1999-07-02 | 2013-10-15 | Genentech, Inc. | Compounds that bind her2 |
SG10201405107YA (en) * | 2006-02-23 | 2014-10-30 | Viacyte Inc | Compositions and methods useful for culturing differentiable cells |
TW201302793A (zh) | 2010-09-03 | 2013-01-16 | Glaxo Group Ltd | 新穎之抗原結合蛋白 |
CN103890007A (zh) * | 2011-08-17 | 2014-06-25 | 霍夫曼-拉罗奇有限公司 | 神经调节蛋白抗体及其用途 |
ES2694153T3 (es) | 2011-09-30 | 2018-12-18 | Regeneron Pharmaceuticals, Inc. | Anticuerpos anti-ErbB3 y usos de los mismos |
US9273143B2 (en) | 2011-09-30 | 2016-03-01 | Regeneron Pharmaceuticals, Inc. | Methods and compositions comprising a combination of an anti-ErbB3 antibody and an anti-EGFR antibody |
EP2727941A1 (en) | 2012-11-05 | 2014-05-07 | MAB Discovery GmbH | Method for the production of multispecific antibodies |
EP2727943A1 (en) | 2012-11-05 | 2014-05-07 | MAB Discovery GmbH | Trispecific antibodies against human EGFR, HER2 and HER3 |
EP2914629A1 (en) | 2012-11-05 | 2015-09-09 | MAB Discovery GmbH | Method for the production of multispecific antibodies |
EP2727942A1 (en) | 2012-11-05 | 2014-05-07 | MAB Discovery GmbH | Bispecific antibodies against human EGFR, HER2, and HER3 |
EP3247380A1 (en) * | 2015-01-20 | 2017-11-29 | Universiteit Antwerpen | Neuregulin in the treatment of fibrotic disorders |
CN113789387B (zh) * | 2021-11-15 | 2022-02-22 | 中国医学科学院北京协和医院 | 标志物在诊断腹主动脉瘤中的用途 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4263428A (en) | 1978-03-24 | 1981-04-21 | The Regents Of The University Of California | Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same |
DE3169595D1 (en) | 1980-11-10 | 1985-05-02 | Gersonde Klaus | Method of preparing lipid vesicles by ultrasonic treatment, the use of this method and apparatus for its application |
US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
EP0088046B1 (de) | 1982-02-17 | 1987-12-09 | Ciba-Geigy Ag | Lipide in wässriger Phase |
EP0102324A3 (de) | 1982-07-29 | 1984-11-07 | Ciba-Geigy Ag | Lipide und Tenside in wässriger Phase |
US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
DE3483949D1 (de) | 1983-09-26 | 1991-02-21 | Udo Dr Med Ehrenfeld | Mittel und erzeugnis fuer die diagnose und therapie von tumoren sowie zur behandlung von schwaechen der zelligen und humoralen immunabwehr. |
EP0143949B1 (en) | 1983-11-01 | 1988-10-12 | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION | Pharmaceutical composition containing urokinase |
US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
US5367060A (en) * | 1991-05-24 | 1994-11-22 | Genentech, Inc. | Structure, production and use of heregulin |
US5770567A (en) * | 1994-11-14 | 1998-06-23 | Genentech, Inc. | Sensory and motor neuron derived factor (SMDF) |
DK0970207T3 (da) * | 1997-02-10 | 2009-07-13 | Genentech Inc | Heregulin-varianter |
-
1999
- 1999-02-03 ES ES99905717T patent/ES2229679T3/es not_active Expired - Lifetime
- 1999-02-03 EP EP99905717A patent/EP1053009B1/en not_active Expired - Lifetime
- 1999-02-03 DE DE69941228T patent/DE69941228D1/de not_active Expired - Lifetime
- 1999-02-03 DE DE69920405T patent/DE69920405T2/de not_active Expired - Lifetime
- 1999-02-03 CA CA2318857A patent/CA2318857C/en not_active Expired - Fee Related
- 1999-02-03 EP EP04022325A patent/EP1510579B1/en not_active Expired - Lifetime
- 1999-02-03 ES ES04022325T patent/ES2329467T3/es not_active Expired - Lifetime
- 1999-02-03 AT AT04022325T patent/ATE438720T1/de active
- 1999-02-03 AU AU25815/99A patent/AU2581599A/en not_active Abandoned
- 1999-02-03 JP JP2000530226A patent/JP4485051B2/ja not_active Expired - Fee Related
- 1999-02-03 WO PCT/US1999/002390 patent/WO1999039729A2/en active IP Right Grant
- 1999-02-03 AT AT99905717T patent/ATE276756T1/de not_active IP Right Cessation
- 1999-02-03 DK DK04022325T patent/DK1510579T3/da active
-
2001
- 2001-02-23 US US09/792,025 patent/US20020042087A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1999039729A2 (en) | 1999-08-12 |
EP1510579A3 (en) | 2005-05-11 |
ATE276756T1 (de) | 2004-10-15 |
AU2581599A (en) | 1999-08-23 |
DE69920405T2 (de) | 2006-01-05 |
ES2229679T3 (es) | 2005-04-16 |
CA2318857A1 (en) | 1999-08-12 |
DE69920405D1 (de) | 2004-10-28 |
CA2318857C (en) | 2013-09-24 |
DE69941228D1 (de) | 2009-09-17 |
US20020042087A1 (en) | 2002-04-11 |
WO1999039729A3 (en) | 1999-10-14 |
ES2329467T3 (es) | 2009-11-26 |
JP2002509076A (ja) | 2002-03-26 |
EP1510579A2 (en) | 2005-03-02 |
JP4485051B2 (ja) | 2010-06-16 |
ATE438720T1 (de) | 2009-08-15 |
EP1053009B1 (en) | 2004-09-22 |
EP1510579B1 (en) | 2009-08-05 |
EP1053009A2 (en) | 2000-11-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1510579T3 (da) | Anvendelse af heregulin som en epitelcellevækstfaktor | |
ATE381943T1 (de) | Zellwachstumsinhibition | |
TR970073A2 (tr) | Alfa adrenerjik resentör antagonistleri olarak pirimidindion pirimidintrion,triazindion, tetrahidrokinazolindion türevleri. | |
LU93311I2 (fr) | Mancozèbe, valifenalate | |
IS5888A (is) | Efnameðferð við krabbameini með asetýldínalíni blönduðu gemsítabíni, kapesítabíni eða sisplatíni | |
GEP20105118B (en) | Anti-vegf antibodies | |
EA200100773A1 (ru) | Замещенные 1-гетероциклические диариламины | |
SV2002000506A (es) | Compuestos de pirimidina pirrolo[2,3-d]ref. pc11027abtc/bb | |
SV2004001432A (es) | 2-tio-3,5-diciano-4-4fenil-6-aminopiridinas substituidas y su uso ref. lea 35 640-sv | |
ID23374A (id) | Halogenopirimidin | |
DE69937509D1 (de) | Mehrschichtige, dekorative Beleuchtung | |
DE59800523D1 (de) | Pulverförmige, vernetzbare Textilbinder-Zusammensetzung | |
EA200100854A1 (ru) | Кальций-литические соединения | |
DE69902493D1 (de) | Härtbare, photochromische Zusammensetzung | |
NO985002D0 (no) | FremgangsmÕte for mottaking, samt mottaker | |
DE10108995A1 (de) | Substituierte Pyrimidinon-Derivate als Liganden von Integrinrezeptoren | |
ES2166045T3 (es) | Procedimiento para la preparacion de compuestos de 4,6-bis(ariloxi)pirimidina asimetricos. | |
SE9902563D0 (sv) | Thermolaminate | |
DE60023582D1 (de) | Trägerfrequenzkorrektur unter Verwendung von Pilotblöcken | |
ES2189390T3 (es) | Fungicidas. | |
DK1436277T3 (da) | Fremgangsmåde til fremstilling af 14beta-hydroxy-baccatin III-1,14-carbonat | |
ES1040702Y (es) | Maquina de cortar losetas de pizarra rectangulares. | |
FR2779456B1 (fr) | Lame niveleuse transporteuse | |
DE59909590D1 (de) | Azidfreie, gaserzeugende zusammensetzung | |
DE69812967D1 (de) | Träger, insbesondere für leuchtdiode |