JP2004501101A - Ｈｅｒ２に対する抗体およびインターロイキン−２の組み合わせの使用による癌の処置 - Google Patents

Ｈｅｒ２に対する抗体およびインターロイキン−２の組み合わせの使用による癌の処置 Download PDF

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Publication number
JP2004501101A
JP2004501101A JP2001583803A JP2001583803A JP2004501101A JP 2004501101 A JP2004501101 A JP 2004501101A JP 2001583803 A JP2001583803 A JP 2001583803A JP 2001583803 A JP2001583803 A JP 2001583803A JP 2004501101 A JP2004501101 A JP 2004501101A
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JP
Japan
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variant
dose
antibody
her2
her2 antibody
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JP2001583803A
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Japanese (ja)
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JP2004501101A5 (https=
Inventor
カリギウリ，　マイケル　エイ．
メロポル，　ニール　ジェイ．
シルスカイ，　リチャード　エル．
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Health Research Inc
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Health Research Inc
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Publication of JP2004501101A5 publication Critical patent/JP2004501101A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2001583803A 2000-05-15 2001-05-15 Ｈｅｒ２に対する抗体およびインターロイキン−２の組み合わせの使用による癌の処置 Pending JP2004501101A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20428400P 2000-05-15 2000-05-15
US09/855,342 US7306801B2 (en) 2000-05-15 2001-05-14 Methods of therapy for cancers characterized by overexpression of the HER2 receptor protein
PCT/US2001/015525 WO2001087336A1 (en) 2000-05-15 2001-05-15 Cancer treatments by using a combination of an antibody against her2 and interleukin -2

Publications (2)

Publication Number Publication Date
JP2004501101A true JP2004501101A (ja) 2004-01-15
JP2004501101A5 JP2004501101A5 (https=) 2008-07-03

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ID=26899337

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JP2001583803A Pending JP2004501101A (ja) 2000-05-15 2001-05-15 Ｈｅｒ２に対する抗体およびインターロイキン−２の組み合わせの使用による癌の処置

Country Status (7)

Country Link
US (2) US7306801B2 (https=)
EP (1) EP1282442A1 (https=)
JP (1) JP2004501101A (https=)
AU (1) AU2001261569A1 (https=)
CA (1) CA2408974A1 (https=)
IL (1) IL152896A0 (https=)
WO (1) WO2001087336A1 (https=)

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Also Published As

Publication number Publication date
US20020031515A1 (en) 2002-03-14
US20080159981A1 (en) 2008-07-03
IL152896A0 (en) 2003-06-24
AU2001261569A1 (en) 2001-11-26
US7306801B2 (en) 2007-12-11
WO2001087336A1 (en) 2001-11-22
EP1282442A1 (en) 2003-02-12
CA2408974A1 (en) 2001-11-22

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