JP2004500037A5 - - Google Patents
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- Publication number
- JP2004500037A5 JP2004500037A5 JP2001521746A JP2001521746A JP2004500037A5 JP 2004500037 A5 JP2004500037 A5 JP 2004500037A5 JP 2001521746 A JP2001521746 A JP 2001521746A JP 2001521746 A JP2001521746 A JP 2001521746A JP 2004500037 A5 JP2004500037 A5 JP 2004500037A5
- Authority
- JP
- Japan
- Prior art keywords
- fgf
- polypeptide
- seq
- nucleic acid
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1999/020594 WO2000015666A2 (en) | 1998-09-10 | 1999-09-08 | Compositions and methods for the treatment of tumors |
| PCT/US1999/021090 WO2000015796A2 (en) | 1998-09-16 | 1999-09-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| PCT/US1999/030999 WO2001005836A1 (en) | 1999-07-20 | 1999-12-20 | Polypeptidic compositions and methods for the treatment of tumors |
| PCT/US2000/004414 WO2001004311A1 (en) | 1999-07-07 | 2000-02-22 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| PCT/US2000/006471 WO2001018210A1 (en) | 1999-09-08 | 2000-03-09 | Fibroblast growth factor-19 (fgf-19) nucleic acids and polypeptides and methods of use for the treatment of obesity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004500037A JP2004500037A (ja) | 2004-01-08 |
| JP2004500037A5 true JP2004500037A5 (https=) | 2007-05-10 |
Family
ID=27485920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001521746A Withdrawn JP2004500037A (ja) | 1999-09-08 | 2000-03-09 | 繊維芽細胞成長因子−１９（ｆｇｆ−１９）核酸及びポリペプチド並びに肥満の治療のための利用の方法 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1214409B1 (https=) |
| JP (1) | JP2004500037A (https=) |
| CN (1) | CN1560249A (https=) |
| CA (1) | CA2384089A1 (https=) |
| DE (1) | DE60028054T2 (https=) |
| ES (1) | ES2264929T3 (https=) |
| WO (1) | WO2001018210A1 (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6716626B1 (en) | 1999-11-18 | 2004-04-06 | Chiron Corporation | Human FGF-21 nucleic acids |
| EP2163626A1 (en) * | 1999-11-18 | 2010-03-17 | Novartis Vaccines and Diagnostics, Inc. | Human FGF-21 gene and gene expression products |
| US6982251B2 (en) | 2000-12-20 | 2006-01-03 | Schering Corporation | Substituted 2-azetidinones useful as hypocholesterolemic agents |
| HU230253B1 (hu) | 2001-01-26 | 2015-11-30 | Merck Sharp & Dohme Corp | Peroxiszóma proliferátor-aktivált receptor (PPAR) aktivátor(ok) és szterin-abszorpció inhibitor(ok) kombinációi és alkalmazásuk vaszkuláris indikációk kezelésére |
| DK1355644T3 (da) | 2001-01-26 | 2006-10-23 | Schering Corp | Anvendelse af substituerede azetidinonforbindelser til behandling af sitosterolæmi |
| US7071181B2 (en) | 2001-01-26 | 2006-07-04 | Schering Corporation | Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors |
| US7456184B2 (en) | 2003-05-01 | 2008-11-25 | Palatin Technologies Inc. | Melanocortin receptor-specific compounds |
| AU2002331064B2 (en) | 2001-08-10 | 2007-08-23 | Palatin Technologies, Inc. | Peptidomimetics of biologically active metallopeptides |
| US7354923B2 (en) | 2001-08-10 | 2008-04-08 | Palatin Technologies, Inc. | Piperazine melanocortin-specific compounds |
| JP2005504091A (ja) | 2001-09-21 | 2005-02-10 | シェーリング コーポレイション | ステロール吸収阻害剤としてアゼチジノンを用いる黄色腫の処置 |
| US7056906B2 (en) | 2001-09-21 | 2006-06-06 | Schering Corporation | Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women |
| US7053080B2 (en) | 2001-09-21 | 2006-05-30 | Schering Corporation | Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors |
| EP1469878B1 (en) * | 2002-01-31 | 2011-03-23 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Fgfr agonists |
| JP2005519947A (ja) * | 2002-03-14 | 2005-07-07 | デヴェロゲン アクチエンゲゼルシャフト フュア エントヴィックルングスビオローギッシェ フォルシュング | エネルギー恒常性の調節に関与するｃｇ８３２７、ｃｇ１０８２３、ｃｇ１８４１８、ｃｇ１５８６２、ｃｇ１６７５０、ｃｇ３７６８およびｃｇ１１４４７相同タンパク質 |
| EP1553912A4 (en) | 2002-06-07 | 2007-08-08 | Genentech Inc | COMPOSITIONS AND METHODS FOR TUMOR DIAGNOSIS AND TREATMENT |
| AU2003274715A1 (en) * | 2002-06-10 | 2003-12-22 | Develogen Aktiengesellschaft Fur Entwicklungsbiologische Forschung | L(2)44 dea, wunen-2, grapes, cg2221, cg1172, rutabaga, cg11940, facl involved in the regulation of energy homeostasis |
| WO2004003179A1 (en) * | 2002-06-27 | 2004-01-08 | The University Of Queensland | Differentiation modulating agents and uses therefor |
| AU2003268116A1 (en) * | 2002-09-18 | 2004-04-08 | Eli Lilly And Company | Method for reducing morbidity and mortality in critically ill patients |
| WO2004043457A1 (en) | 2002-11-06 | 2004-05-27 | Schering Corporation | Cholesterol absorptions inhibitors for the treatment of autoimmune disorders |
| EP1572227B1 (en) * | 2002-12-16 | 2012-02-15 | DeveloGen Aktiengesellschaft | Pik4cb involved in the regulation of energy homeostasis |
| JP4589919B2 (ja) | 2003-03-07 | 2010-12-01 | シェーリング コーポレイション | 高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用 |
| CA2517571C (en) | 2003-03-07 | 2011-07-05 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
| JP2006519869A (ja) | 2003-03-07 | 2006-08-31 | シェーリング コーポレイション | 置換アゼチジノン化合物、置換アゼチジノン化合物を調製するためのプロセス、それらの処方物および使用 |
| US7459442B2 (en) | 2003-03-07 | 2008-12-02 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
| EP2060270A3 (en) * | 2003-10-16 | 2009-12-09 | Imclone LLC | Fibroblast growth factor receptor-1 inhibitors and methods of treatment thereof |
| ES2582652T3 (es) | 2006-02-10 | 2016-09-14 | Genentech, Inc. | Anticuerpos anti-FGF19 y métodos de uso de los mismos |
| US8236307B2 (en) | 2007-08-03 | 2012-08-07 | Genentech, Inc. | Humanized anti-FGF19 antagonists and methods using same |
| WO2009046141A2 (en) | 2007-10-01 | 2009-04-09 | Isis Pharmaceuticals, Inc. | Antisense modulation of fibroblast growth factor receptor 4 expression |
| JP6043347B2 (ja) | 2011-06-16 | 2016-12-14 | アイオーニス ファーマシューティカルズ， インコーポレーテッドＩｏｎｉｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | 線維芽細胞増殖因子受容体４の発現のアンチセンス調節 |
| TWI670283B (zh) | 2013-12-23 | 2019-09-01 | 美商建南德克公司 | 抗體及使用方法 |
| CN113105561B (zh) | 2021-04-30 | 2021-12-03 | 江南大学 | 一种双靶点融合蛋白的制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999014327A2 (en) * | 1997-09-17 | 1999-03-25 | Genentech, Inc. | Genes amplified in tumours, antibodies against the proteins coded thereby, and their use in diagnosis and treatment of cancer |
| NZ503343A (en) * | 1997-09-17 | 2002-09-27 | Genentech Inc | Secreted and transmembrane polypeptides and use to induce apoptosis of tumour cells |
| KR20050009764A (ko) * | 1997-11-25 | 2005-01-25 | 제넨테크, 인크. | 섬유아세포 성장 인자-19 |
-
2000
- 2000-03-09 EP EP00917878A patent/EP1214409B1/en not_active Expired - Lifetime
- 2000-03-09 WO PCT/US2000/006471 patent/WO2001018210A1/en not_active Ceased
- 2000-03-09 DE DE60028054T patent/DE60028054T2/de not_active Expired - Lifetime
- 2000-03-09 ES ES00917878T patent/ES2264929T3/es not_active Expired - Lifetime
- 2000-03-09 CN CNA2004100465359A patent/CN1560249A/zh active Pending
- 2000-03-09 CA CA002384089A patent/CA2384089A1/en not_active Abandoned
- 2000-03-09 JP JP2001521746A patent/JP2004500037A/ja not_active Withdrawn
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