CN1560249A - 成纤维细胞生长因子-19（fgf-19）的核酸和多肽以及用于治疗肥胖的方法 - Google Patents

成纤维细胞生长因子-19（fgf-19）的核酸和多肽以及用于治疗肥胖的方法 Download PDF

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Publication number
CN1560249A
CN1560249A CNA2004100465359A CN200410046535A CN1560249A CN 1560249 A CN1560249 A CN 1560249A CN A2004100465359 A CNA2004100465359 A CN A2004100465359A CN 200410046535 A CN200410046535 A CN 200410046535A CN 1560249 A CN1560249 A CN 1560249A
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fgf
polypeptide
sequence
antibody
nucleic acid
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Pending
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CNA2004100465359A
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Chinese (zh)
Inventor
蒂莫西・A・斯图尔特
蒂莫西·A·斯图尔特
白・汤姆林森
伊丽莎白·汤姆林森
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Genentech Inc
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Genentech Inc
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Priority claimed from PCT/US1999/020594 external-priority patent/WO2000015666A2/en
Priority claimed from PCT/US1999/021090 external-priority patent/WO2000015796A2/en
Priority claimed from PCT/US1999/030999 external-priority patent/WO2001005836A1/en
Priority claimed from PCT/US2000/004414 external-priority patent/WO2001004311A1/en
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CN1560249A publication Critical patent/CN1560249A/zh
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CNA2004100465359A 1999-09-08 2000-03-09 成纤维细胞生长因子-19（fgf-19）的核酸和多肽以及用于治疗肥胖的方法 Pending CN1560249A (zh)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
USPCT/US99/20594 1999-09-08
PCT/US1999/020594 WO2000015666A2 (en) 1998-09-10 1999-09-08 Compositions and methods for the treatment of tumors
USPCT/US99/21090 1999-09-15
PCT/US1999/021090 WO2000015796A2 (en) 1998-09-16 1999-09-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
USPCT/US99/30999 1999-12-20
PCT/US1999/030999 WO2001005836A1 (en) 1999-07-20 1999-12-20 Polypeptidic compositions and methods for the treatment of tumors
USPCT/US00/04414 2000-02-22
PCT/US2000/004414 WO2001004311A1 (en) 1999-07-07 2000-02-22 Secreted and transmembrane polypeptides and nucleic acids encoding the same

Related Parent Applications (1)

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CN00815274A Division CN1387570A (zh) 1999-09-08 2000-03-09 成纤维细胞生长因子－19(fgf－19)的核酸和多肽以及用于治疗肥胖的方法

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CN1560249A true CN1560249A (zh) 2005-01-05

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CNA2004100465359A Pending CN1560249A (zh) 1999-09-08 2000-03-09 成纤维细胞生长因子-19（fgf-19）的核酸和多肽以及用于治疗肥胖的方法

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EP (1) EP1214409B1 (https=)
JP (1) JP2004500037A (https=)
CN (1) CN1560249A (https=)
CA (1) CA2384089A1 (https=)
DE (1) DE60028054T2 (https=)
ES (1) ES2264929T3 (https=)
WO (1) WO2001018210A1 (https=)

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CN113105561A (zh) * 2021-04-30 2021-07-13 江南大学 一种双靶点融合蛋白的制备方法和应用

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US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
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US7354923B2 (en) 2001-08-10 2008-04-08 Palatin Technologies, Inc. Piperazine melanocortin-specific compounds
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WO2004043457A1 (en) 2002-11-06 2004-05-27 Schering Corporation Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
EP1572227B1 (en) * 2002-12-16 2012-02-15 DeveloGen Aktiengesellschaft Pik4cb involved in the regulation of energy homeostasis
JP4589919B2 (ja) 2003-03-07 2010-12-01 シェーリング コーポレイション 高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用
CA2517571C (en) 2003-03-07 2011-07-05 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP2006519869A (ja) 2003-03-07 2006-08-31 シェーリング　コーポレイション 置換アゼチジノン化合物、置換アゼチジノン化合物を調製するためのプロセス、それらの処方物および使用
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
EP2060270A3 (en) * 2003-10-16 2009-12-09 Imclone LLC Fibroblast growth factor receptor-1 inhibitors and methods of treatment thereof
ES2582652T3 (es) 2006-02-10 2016-09-14 Genentech, Inc. Anticuerpos anti-FGF19 y métodos de uso de los mismos
US8236307B2 (en) 2007-08-03 2012-08-07 Genentech, Inc. Humanized anti-FGF19 antagonists and methods using same
WO2009046141A2 (en) 2007-10-01 2009-04-09 Isis Pharmaceuticals, Inc. Antisense modulation of fibroblast growth factor receptor 4 expression
JP6043347B2 (ja) 2011-06-16 2016-12-14 アイオーニス ファーマシューティカルズ， インコーポレーテッドＩｏｎｉｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． 線維芽細胞増殖因子受容体４の発現のアンチセンス調節
TWI670283B (zh) 2013-12-23 2019-09-01 美商建南德克公司 抗體及使用方法

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113105561A (zh) * 2021-04-30 2021-07-13 江南大学 一种双靶点融合蛋白的制备方法和应用
US11845781B2 (en) 2021-04-30 2023-12-19 Jiangnan University Fusion protein comprising fibroblast growth factor 19 (FGF 19) and glucagon-like peptide-1

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WO2001018210A1 (en) 2001-03-15
DE60028054D1 (de) 2006-06-22
JP2004500037A (ja) 2004-01-08
CA2384089A1 (en) 2001-03-15
EP1214409A1 (en) 2002-06-19
ES2264929T3 (es) 2007-02-01
EP1214409B1 (en) 2006-05-17

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