JP2004065264A5 - - Google Patents
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- Publication number
- JP2004065264A5 JP2004065264A5 JP2003292590A JP2003292590A JP2004065264A5 JP 2004065264 A5 JP2004065264 A5 JP 2004065264A5 JP 2003292590 A JP2003292590 A JP 2003292590A JP 2003292590 A JP2003292590 A JP 2003292590A JP 2004065264 A5 JP2004065264 A5 JP 2004065264A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nucleic acid
- protein
- calcium
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000007523 nucleic acids Chemical class 0.000 claims 44
- 108020004707 nucleic acids Proteins 0.000 claims 34
- 102000039446 nucleic acids Human genes 0.000 claims 34
- 108090000623 proteins and genes Proteins 0.000 claims 26
- 102000004169 proteins and genes Human genes 0.000 claims 25
- 108091006146 Channels Proteins 0.000 claims 20
- 238000000034 method Methods 0.000 claims 20
- 108010045489 Calcium-Activated Potassium Channels Proteins 0.000 claims 19
- 102000005702 Calcium-Activated Potassium Channels Human genes 0.000 claims 19
- 102000034573 Channels Human genes 0.000 claims 17
- 210000004027 cell Anatomy 0.000 claims 10
- 238000009396 hybridization Methods 0.000 claims 10
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 9
- 150000001413 amino acids Chemical class 0.000 claims 8
- 239000000178 monomer Substances 0.000 claims 8
- 210000000170 cell membrane Anatomy 0.000 claims 6
- 150000001875 compounds Chemical class 0.000 claims 6
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- 210000000287 oocyte Anatomy 0.000 claims 5
- 125000000539 amino acid group Chemical group 0.000 claims 4
- 239000011575 calcium Substances 0.000 claims 4
- 229910052791 calcium Inorganic materials 0.000 claims 4
- 239000002773 nucleotide Substances 0.000 claims 4
- 125000003729 nucleotide group Chemical group 0.000 claims 4
- 229910001414 potassium ion Inorganic materials 0.000 claims 4
- 102000004257 Potassium Channel Human genes 0.000 claims 3
- 239000012472 biological sample Substances 0.000 claims 3
- 229920001002 functional polymer Polymers 0.000 claims 3
- 108020001213 potassium channel Proteins 0.000 claims 3
- 239000000523 sample Substances 0.000 claims 3
- 239000013598 vector Substances 0.000 claims 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 2
- -1 Calcium-activated potassium Chemical class 0.000 claims 2
- 102000007008 Intermediate-Conductance Calcium-Activated Potassium Channels Human genes 0.000 claims 2
- 108010033149 Intermediate-Conductance Calcium-Activated Potassium Channels Proteins 0.000 claims 2
- 108020004711 Nucleic Acid Probes Proteins 0.000 claims 2
- NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 230000007423 decrease Effects 0.000 claims 2
- 230000003247 decreasing effect Effects 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 230000004907 flux Effects 0.000 claims 2
- 239000002853 nucleic acid probe Substances 0.000 claims 2
- 101100150099 Caenorhabditis elegans spk-1 gene Proteins 0.000 claims 1
- 101000974731 Homo sapiens Small conductance calcium-activated potassium channel protein 1 Proteins 0.000 claims 1
- 101001026230 Homo sapiens Small conductance calcium-activated potassium channel protein 2 Proteins 0.000 claims 1
- 101001026232 Homo sapiens Small conductance calcium-activated potassium channel protein 3 Proteins 0.000 claims 1
- 206010035148 Plague Diseases 0.000 claims 1
- 102100022747 Small conductance calcium-activated potassium channel protein 1 Human genes 0.000 claims 1
- 102100037446 Small conductance calcium-activated potassium channel protein 2 Human genes 0.000 claims 1
- 102100037442 Small conductance calcium-activated potassium channel protein 3 Human genes 0.000 claims 1
- 241000607479 Yersinia pestis Species 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims 1
- 230000001900 immune effect Effects 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- 230000035772 mutation Effects 0.000 claims 1
- 230000009257 reactivity Effects 0.000 claims 1
- 230000003252 repetitive effect Effects 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2645196P | 1996-09-11 | 1996-09-11 | |
| US4005297P | 1997-03-07 | 1997-03-07 | |
| US4523397P | 1997-04-17 | 1997-04-17 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51382898A Division JP4052525B2 (ja) | 1996-09-11 | 1997-09-10 | 低及び中間コンダクタンスのカルシウム活性化されたカリウムチャネル及びその使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006194963A Division JP2006320333A (ja) | 1996-09-11 | 2006-07-14 | 低及び中間コンダクタンスのカルシウム活性化されたカリウムチャネル及びその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004065264A JP2004065264A (ja) | 2004-03-04 |
| JP2004065264A5 true JP2004065264A5 (enExample) | 2005-05-26 |
Family
ID=27362774
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51382898A Expired - Fee Related JP4052525B2 (ja) | 1996-09-11 | 1997-09-10 | 低及び中間コンダクタンスのカルシウム活性化されたカリウムチャネル及びその使用 |
| JP2003292589A Expired - Fee Related JP4052582B2 (ja) | 1996-09-11 | 2003-08-12 | 低及び中間コンダクタンスのカルシウム活性化されたカリウムチャネル及びその使用 |
| JP2003292590A Withdrawn JP2004065264A (ja) | 1996-09-11 | 2003-08-12 | 低及び中間コンダクタンスのカルシウム活性化されたカリウムチャネル及びその使用 |
| JP2006194963A Pending JP2006320333A (ja) | 1996-09-11 | 2006-07-14 | 低及び中間コンダクタンスのカルシウム活性化されたカリウムチャネル及びその使用 |
| JP2007259280A Withdrawn JP2008092950A (ja) | 1996-09-11 | 2007-10-02 | 低及び中間コンダクタンスのカルシウム活性化されたカリウムチャネル及びその使用 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51382898A Expired - Fee Related JP4052525B2 (ja) | 1996-09-11 | 1997-09-10 | 低及び中間コンダクタンスのカルシウム活性化されたカリウムチャネル及びその使用 |
| JP2003292589A Expired - Fee Related JP4052582B2 (ja) | 1996-09-11 | 2003-08-12 | 低及び中間コンダクタンスのカルシウム活性化されたカリウムチャネル及びその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006194963A Pending JP2006320333A (ja) | 1996-09-11 | 2006-07-14 | 低及び中間コンダクタンスのカルシウム活性化されたカリウムチャネル及びその使用 |
| JP2007259280A Withdrawn JP2008092950A (ja) | 1996-09-11 | 2007-10-02 | 低及び中間コンダクタンスのカルシウム活性化されたカリウムチャネル及びその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (9) | US6797486B2 (enExample) |
| EP (1) | EP0948542B1 (enExample) |
| JP (5) | JP4052525B2 (enExample) |
| AT (1) | ATE366260T1 (enExample) |
| AU (1) | AU726158B2 (enExample) |
| CA (1) | CA2265485C (enExample) |
| DE (2) | DE69737889T2 (enExample) |
| WO (1) | WO1998011139A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU8348498A (en) * | 1997-07-15 | 1999-02-10 | Zeneca Limited | Methods |
| AU742407B2 (en) * | 1997-07-15 | 2002-01-03 | Regents Of The University Of California, The | Isolated DNA encoding human calcium activated potassium channel |
| WO2001094390A2 (en) * | 2000-06-06 | 2001-12-13 | Millennium Pharmaceuticals, Inc. | 52906, 33408, and 12189, potassium channel family members and uses thereof |
| CA2433041A1 (en) * | 2000-12-28 | 2002-07-11 | Switch Biotech Aktiengesellschaft | Use of intermediate-conductance potassium channels and modulators for diagnosing and treating diseases involving disturbed keratinocyte activiyty |
| US7022480B1 (en) * | 2001-10-11 | 2006-04-04 | The Regents Of The University Of California | Exons of the hSKCa3/KCNN3 gene |
| WO2005043973A2 (en) * | 2003-10-28 | 2005-05-19 | Janssen Pharmaceutica Nv | Assay systems and methods for detecting molecules that interact with sk2 channels |
| EP1884774A1 (en) * | 2006-08-03 | 2008-02-06 | INSERM (Institut National de la Santé et de la Recherche Medicale) | A method for the in vitro screening of anti-cancer compounds that inhibits SK3 activity, and said anti-cancer compounds |
| CN110378549B (zh) * | 2019-05-31 | 2023-05-23 | 广东工业大学 | 一种基于fahp-熵权法的输电杆塔鸟害等级评估方法 |
| CN121057823A (zh) * | 2023-04-10 | 2025-12-02 | 耶鲁大学 | 体内修饰神经元以治疗和/或预防肌萎缩性侧索硬化(als)的方法 |
| WO2025175135A1 (en) * | 2024-02-15 | 2025-08-21 | Yale University | Modifying neurons to treat or prevent parkinson's disease |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT392957B (de) | 1987-08-06 | 1991-07-25 | Technoagrar Consulting Ag | Verfahren zur behandlung und entsorgung von gemengen aus feststoffen und fluessigkeiten |
| US6307030B1 (en) * | 1988-04-15 | 2001-10-23 | The University Of North Carolina At Chapel Hill | Androgen receptor proteins, recombinant DNA molecules coding for such, and use of such compositions |
| CA2116280A1 (en) * | 1993-03-05 | 1994-09-06 | Marcy E. Macdonald | Huntingtin dna, protein and uses thereof |
| US5519003A (en) * | 1994-02-01 | 1996-05-21 | Board Of Trustees Of The Leland Stanford Junior University | WD-40-derived peptides and uses thereof |
| US6277978B1 (en) * | 1995-12-22 | 2001-08-21 | University Of Utah Research Foundation | KVLQT1—a long QT syndrome gene |
| AU8348498A (en) | 1997-07-15 | 1999-02-10 | Zeneca Limited | Methods |
| AU742407B2 (en) * | 1997-07-15 | 2002-01-03 | Regents Of The University Of California, The | Isolated DNA encoding human calcium activated potassium channel |
| AU1224599A (en) | 1997-11-14 | 1999-06-07 | Neurosearch A/S | Chemical compounds having ion channel blocking activity for the treatment of immune dysfunction |
-
1997
- 1997-09-10 US US09/254,590 patent/US6797486B2/en not_active Expired - Fee Related
- 1997-09-10 WO PCT/US1997/016033 patent/WO1998011139A1/en not_active Ceased
- 1997-09-10 JP JP51382898A patent/JP4052525B2/ja not_active Expired - Fee Related
- 1997-09-10 AU AU42660/97A patent/AU726158B2/en not_active Ceased
- 1997-09-10 DE DE69737889T patent/DE69737889T2/de not_active Expired - Lifetime
- 1997-09-10 AT AT97941009T patent/ATE366260T1/de not_active IP Right Cessation
- 1997-09-10 DE DE69739956T patent/DE69739956D1/de not_active Expired - Lifetime
- 1997-09-10 CA CA002265485A patent/CA2265485C/en not_active Expired - Fee Related
- 1997-09-10 EP EP97941009A patent/EP0948542B1/en not_active Expired - Lifetime
-
2001
- 2001-08-03 US US09/922,364 patent/US6692937B2/en not_active Expired - Fee Related
-
2002
- 2002-04-02 US US10/115,415 patent/US6828122B2/en not_active Expired - Fee Related
- 2002-04-03 US US10/115,671 patent/US6828420B2/en not_active Expired - Fee Related
- 2002-04-03 US US10/115,695 patent/US6894147B2/en not_active Expired - Fee Related
- 2002-04-03 US US10/116,561 patent/US6987169B2/en not_active Expired - Fee Related
- 2002-04-03 US US10/116,260 patent/US6828123B2/en not_active Expired - Fee Related
- 2002-04-03 US US10/115,688 patent/US7026451B2/en not_active Expired - Fee Related
-
2003
- 2003-08-12 JP JP2003292589A patent/JP4052582B2/ja not_active Expired - Fee Related
- 2003-08-12 JP JP2003292590A patent/JP2004065264A/ja not_active Withdrawn
-
2005
- 2005-04-27 US US11/116,760 patent/US7534869B2/en not_active Expired - Fee Related
-
2006
- 2006-07-14 JP JP2006194963A patent/JP2006320333A/ja active Pending
-
2007
- 2007-10-02 JP JP2007259280A patent/JP2008092950A/ja not_active Withdrawn
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