JP2006501479A5 - - Google Patents
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- Publication number
- JP2006501479A5 JP2006501479A5 JP2004541914A JP2004541914A JP2006501479A5 JP 2006501479 A5 JP2006501479 A5 JP 2006501479A5 JP 2004541914 A JP2004541914 A JP 2004541914A JP 2004541914 A JP2004541914 A JP 2004541914A JP 2006501479 A5 JP2006501479 A5 JP 2006501479A5
- Authority
- JP
- Japan
- Prior art keywords
- neoepitope
- antibody
- ratio
- binding
- osteoarthritis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 10
- 201000008482 osteoarthritis Diseases 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 2
- IHUKVJKKTBLTEE-QMMMGPOBSA-N (2s)-2-acetamido-5-[[amino-(methylcarbamoylamino)methylidene]amino]-n-methylpentanamide Chemical compound CNC(=O)NC(N)=NCCC[C@H](NC(C)=O)C(=O)NC IHUKVJKKTBLTEE-QMMMGPOBSA-N 0.000 claims 1
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 102000012422 Collagen Type I Human genes 0.000 claims 1
- 108010022452 Collagen Type I Proteins 0.000 claims 1
- 102000000503 Collagen Type II Human genes 0.000 claims 1
- 108010041390 Collagen Type II Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 208000003947 Knee Osteoarthritis Diseases 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 238000003776 cleavage reaction Methods 0.000 claims 1
- 230000007017 scission Effects 0.000 claims 1
- 230000009885 systemic effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41432402P | 2002-09-30 | 2002-09-30 | |
| PCT/US2003/030853 WO2004031725A2 (en) | 2002-09-30 | 2003-09-30 | Ratios of collagen peptides, their uses and products |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006501479A JP2006501479A (ja) | 2006-01-12 |
| JP2006501479A5 true JP2006501479A5 (enExample) | 2006-10-19 |
Family
ID=32069723
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004541914A Pending JP2006501479A (ja) | 2002-09-30 | 2003-09-30 | コラーゲンペプチドの比、それらの使用および生成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20040132064A1 (enExample) |
| EP (1) | EP1549354A4 (enExample) |
| JP (1) | JP2006501479A (enExample) |
| KR (1) | KR20050084608A (enExample) |
| AU (1) | AU2003279076A1 (enExample) |
| CA (1) | CA2500670A1 (enExample) |
| WO (1) | WO2004031725A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7892768B2 (en) * | 2007-03-02 | 2011-02-22 | Anamar Medical Ab | Diagnosis of collagen IX destruction |
| US20100298329A1 (en) * | 2007-09-19 | 2010-11-25 | Massachusette Institute Of Technology | Tolperisone and tolperisone-like drugs for the treatment of k-ras associated cancers |
| JP2009257842A (ja) * | 2008-04-14 | 2009-11-05 | Ttc:Kk | 変形性関節症の検査方法及び診断用キット |
| GB0820786D0 (en) * | 2008-11-13 | 2008-12-24 | Nordic Bioscience As | Assessment of protein degradation by measurement of collagen fragments |
| GB201016050D0 (en) * | 2010-09-24 | 2010-11-10 | Nordic Bioscience As | Assay for a type II collagen biomarker in serum |
| WO2015009754A2 (en) | 2013-07-15 | 2015-01-22 | Svoboda Steven J | Methods and apparatus for assessment of risk for joint injury |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6132976A (en) * | 1992-12-04 | 2000-10-17 | Shriners Hospitals For Children | Immunoassays for the measurement of collagen denaturation and cleavage in cartilage |
| IE970801A1 (en) * | 1997-11-11 | 1999-05-19 | Helsinn Chemicals Ireland Ltd | An apparatus for producing a pharmaceutical product |
-
2003
- 2003-09-30 US US10/673,647 patent/US20040132064A1/en not_active Abandoned
- 2003-09-30 AU AU2003279076A patent/AU2003279076A1/en not_active Abandoned
- 2003-09-30 KR KR1020057005375A patent/KR20050084608A/ko not_active Withdrawn
- 2003-09-30 CA CA002500670A patent/CA2500670A1/en not_active Abandoned
- 2003-09-30 JP JP2004541914A patent/JP2006501479A/ja active Pending
- 2003-09-30 WO PCT/US2003/030853 patent/WO2004031725A2/en not_active Ceased
- 2003-09-30 EP EP03770587A patent/EP1549354A4/en not_active Withdrawn
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