JP2003535025A5 - - Google Patents

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Publication number
JP2003535025A5
JP2003535025A5 JP2001506851A JP2001506851A JP2003535025A5 JP 2003535025 A5 JP2003535025 A5 JP 2003535025A5 JP 2001506851 A JP2001506851 A JP 2001506851A JP 2001506851 A JP2001506851 A JP 2001506851A JP 2003535025 A5 JP2003535025 A5 JP 2003535025A5
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JP
Japan
Prior art keywords
organ
micro
mammal
tissue
polynucleotide sequence
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Pending
Application number
JP2001506851A
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English (en)
Japanese (ja)
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JP2003535025A (ja
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Publication date
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Priority claimed from PCT/IL2000/000365 external-priority patent/WO2001000859A1/en
Publication of JP2003535025A publication Critical patent/JP2003535025A/ja
Publication of JP2003535025A5 publication Critical patent/JP2003535025A5/ja
Pending legal-status Critical Current

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JP2001506851A 1999-06-25 2000-06-22 微小器官で血管新生を誘発する方法 Pending JP2003535025A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14074899P 1999-06-25 1999-06-25
US60/140,748 1999-06-25
PCT/IL2000/000365 WO2001000859A1 (en) 1999-06-25 2000-06-22 Method of inducing angiogenesis by micro-organs

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2003305960A Division JP2004073206A (ja) 1999-06-25 2003-08-29 遺伝的に改変された微小器官外植片、その生産方法およびその使用
JP2010271065A Division JP2011087592A (ja) 1999-06-25 2010-12-06 微小器官外植片、及びその生産方法

Publications (2)

Publication Number Publication Date
JP2003535025A JP2003535025A (ja) 2003-11-25
JP2003535025A5 true JP2003535025A5 (https=) 2007-08-02

Family

ID=22492636

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2001506851A Pending JP2003535025A (ja) 1999-06-25 2000-06-22 微小器官で血管新生を誘発する方法
JP2003305960A Pending JP2004073206A (ja) 1999-06-25 2003-08-29 遺伝的に改変された微小器官外植片、その生産方法およびその使用
JP2010271065A Pending JP2011087592A (ja) 1999-06-25 2010-12-06 微小器官外植片、及びその生産方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2003305960A Pending JP2004073206A (ja) 1999-06-25 2003-08-29 遺伝的に改変された微小器官外植片、その生産方法およびその使用
JP2010271065A Pending JP2011087592A (ja) 1999-06-25 2010-12-06 微小器官外植片、及びその生産方法

Country Status (7)

Country Link
US (1) US20030086914A1 (https=)
EP (2) EP1190082A4 (https=)
JP (3) JP2003535025A (https=)
CN (1) CN1420933A (https=)
AU (1) AU5423300A (https=)
CA (2) CA2377541A1 (https=)
WO (1) WO2001000859A1 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030157074A1 (en) * 1994-11-16 2003-08-21 Mitrani Eduardo N. Vitro micro-organs, and uses related thereto
WO2003035851A1 (en) * 2001-10-23 2003-05-01 Yissum Research Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs, and uses related thereto
US7687057B2 (en) * 1998-01-09 2010-03-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs, and uses related thereto
US20030152562A1 (en) * 2001-10-23 2003-08-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Vitro micro-organs, and uses related thereto
US20060127366A1 (en) * 1999-06-25 2006-06-15 Mitrani Eduardo N Method and device for inducing biological processes by micro-organs
US7468242B2 (en) 2001-11-05 2008-12-23 Medgenics, Inc. Dermal micro organs, methods and apparatuses for producing and using the same
US8088568B2 (en) 2001-11-05 2012-01-03 Medgentics, Inc. Dermal micro-organs, methods and apparatuses for producing and using the same
US8501396B2 (en) 2001-11-05 2013-08-06 Medgenics Medical Israel Ltd. Dermal micro-organs, methods and apparatuses for producing and using the same
JP4447916B2 (ja) * 2001-11-05 2010-04-07 メドジニックス・インコーポレイテッド 微小器官処理システム及びそれを用いた微小器官の製造方法
US7297540B2 (en) 2002-01-15 2007-11-20 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of generating tissue using devitalized, acellular scaffold matrices derived from micro-organs
HRP20120673T1 (hr) 2003-05-01 2012-10-31 Medgenics, Inc. Uporaba dermalnih mikroorgana
IL155783A (en) 2003-05-05 2010-11-30 Technion Res & Dev Foundation Multicellular systems of pluripotent human embryonic stem cells and cancer cells and uses thereof
US20050244967A1 (en) * 2004-05-03 2005-11-03 Pearlman Andrew L Closed automated system for tissue based therapy
US7638273B2 (en) 2005-10-18 2009-12-29 Caritas St. Elizabeth's Medical Center Of Boston, Inc. Generation and use of vasculogenic tumors and products derived from same
US8038595B2 (en) 2006-01-25 2011-10-18 Beth Israel Deaconess Medical Center Devices and methods for tissue transplant and regeneration
CN102886052B (zh) 2006-09-14 2014-07-30 迈德詹尼克斯医疗以色列有限公司 长效药物制剂
US8454948B2 (en) 2006-09-14 2013-06-04 Medgenics Medical Israel Ltd. Long lasting drug formulations
IL196820A0 (en) 2009-02-01 2009-11-18 Yissum Res Dev Co Devitalized, acellular scaffold matrices derived from micro-organs seeded with various cells
CA2802726A1 (en) 2010-06-15 2011-12-22 Medgenics Medical Israel Ltd. Long lasting drug formulations
JP2017195778A (ja) * 2014-09-01 2017-11-02 株式会社オーガンテクノロジーズ 三次元血管網を有する器官をｉｎｖｉｖｏで形成させる方法、及び、三次元血管網を有する器官の形成用組成物
CN111500447B (zh) * 2020-04-26 2023-06-06 广东康盾创新产业集团股份公司 一种用于免疫细胞扩增的细胞培养装置
CN111588423A (zh) * 2020-06-08 2020-08-28 刘绍才 一种可微调切割面积的病变细胞组织切除装置
CN114812463B (zh) * 2022-06-27 2022-09-30 山西嘉世达机器人技术有限公司 检测清洁机到达边缘的方法、检测装置、清洁机和介质

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154600B (nl) * 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
NL154598B (nl) * 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
NL154599B (nl) * 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
US3901654A (en) * 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
US3853987A (en) * 1971-09-01 1974-12-10 W Dreyer Immunological reagent and radioimmuno assay
US3867517A (en) * 1971-12-21 1975-02-18 Abbott Lab Direct radioimmunoassay for antigens and their antibodies
US3850578A (en) * 1973-03-12 1974-11-26 H Mcconnell Process for assaying for biologically active molecules
US3935074A (en) * 1973-12-17 1976-01-27 Syva Company Antibody steric hindrance immunoassay with two antibodies
US3996345A (en) * 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4034074A (en) * 1974-09-19 1977-07-05 The Board Of Trustees Of Leland Stanford Junior University Universal reagent 2-site immunoradiometric assay using labelled anti (IgG)
US3984533A (en) * 1975-11-13 1976-10-05 General Electric Company Electrophoretic method of detecting antigen-antibody reaction
US4098876A (en) * 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4391909A (en) * 1979-03-28 1983-07-05 Damon Corporation Microcapsules containing viable tissue cells
US4879219A (en) * 1980-09-19 1989-11-07 General Hospital Corporation Immunoassay utilizing monoclonal high affinity IgM antibodies
US4353888A (en) * 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
JPS59134728A (ja) * 1983-01-21 1984-08-02 Seiji Takayama 免疫抗癌剤及びその製法
US5011771A (en) * 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
US4736866B1 (en) * 1984-06-22 1988-04-12 Transgenic non-human mammals
US4666828A (en) * 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
JPS61233694A (ja) * 1985-04-08 1986-10-17 Morinaga & Co Ltd ウシ脾臓中に含まれる成長因子及びその単離方法
US4801531A (en) * 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
US4883666A (en) * 1987-04-29 1989-11-28 Massachusetts Institute Of Technology Controlled drug delivery system for treatment of neural disorders
DE3854823T2 (de) * 1987-05-01 1996-05-23 Stratagene Inc Mutagenesetest durch Verwendung von nicht menschlichen Lebewesen, die Test-DNS-Sequenzen enthalten
US5175385A (en) * 1987-09-03 1992-12-29 Ohio University/Edison Animal Biotechnolgy Center Virus-resistant transgenic mice
US4892538A (en) * 1987-11-17 1990-01-09 Brown University Research Foundation In vivo delivery of neurotransmitters by implanted, encapsulated cells
US5106627A (en) * 1987-11-17 1992-04-21 Brown University Research Foundation Neurological therapy devices
US5055296A (en) * 1988-08-04 1991-10-08 Wagle Sudhakar S Method of treating chronic fatigue syndrome
US5221778A (en) * 1988-08-24 1993-06-22 Yale University Multiplex gene regulation
US5272057A (en) * 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5175384A (en) * 1988-12-05 1992-12-29 Genpharm International Transgenic mice depleted in mature t-cells and methods for making transgenic mice
US5175383A (en) * 1989-02-17 1992-12-29 President And Fellows Of Harvard College Animal model for benign prostatic disease
US5464764A (en) * 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
US5192659A (en) * 1989-08-25 1993-03-09 Genetype Ag Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
ES2217250T3 (es) * 1990-06-15 2004-11-01 Scios Inc. Mamifero transgenico, no humano que muestra la patologia de formacion amiloides de la enfermedad de alzheimer.
US5288846A (en) * 1990-10-19 1994-02-22 The General Hospital Corporation Cell specific gene regulators
US5298422A (en) * 1991-11-06 1994-03-29 Baylor College Of Medicine Myogenic vector systems
US5281521A (en) * 1992-07-20 1994-01-25 The Trustees Of The University Of Pennsylvania Modified avidin-biotin technique
US5888720A (en) * 1992-10-27 1999-03-30 Yissum Research And Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs
US6472200B1 (en) * 1999-07-23 2002-10-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Device and method for performing a biological modification of a fluid
US20030152909A1 (en) * 1994-11-16 2003-08-14 Mitrani Eduardo N. In vitro micro-organs, and uses related thereto
US20030157074A1 (en) * 1994-11-16 2003-08-21 Mitrani Eduardo N. Vitro micro-organs, and uses related thereto
US6090618A (en) * 1996-10-07 2000-07-18 Arch Development Corporation DNA constructs and viral vectors comprising a smooth muscle promoter
JP4046358B2 (ja) * 1996-12-10 2008-02-13 パーデュー・リサーチ・ファウンデーション 粘膜下組織抽出物
CA2279996A1 (en) * 1997-01-16 1998-07-16 Yissum Research Development Company Of The Hebrew University In Jerusale M A device and method for performing a biological modification of a fluid
US6486133B1 (en) * 1997-03-07 2002-11-26 The Wistar Institute Of Anatomy And Biology Methods for inducing localized vascular development and enhancing the repair of a wound in the mammamian dermis
US6110459A (en) * 1997-05-28 2000-08-29 Mickle; Donald A. G. Transplants for myocardial scars and methods and cellular preparations
JP2001511462A (ja) * 1997-07-31 2001-08-14 セント エリザベス メディカル センター オブ ボストン インク． 移植片処置法
CN1275050A (zh) * 1997-08-15 2000-11-29 路德维格癌症研究所 内皮蛋白酶解活性和/或血管生成活性的刺激、调节和/或抑制
US7687057B2 (en) * 1998-01-09 2010-03-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs, and uses related thereto
US20030152562A1 (en) * 2001-10-23 2003-08-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Vitro micro-organs, and uses related thereto

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