JP2003529317A5 - - Google Patents
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- Publication number
- JP2003529317A5 JP2003529317A5 JP2000589692A JP2000589692A JP2003529317A5 JP 2003529317 A5 JP2003529317 A5 JP 2003529317A5 JP 2000589692 A JP2000589692 A JP 2000589692A JP 2000589692 A JP2000589692 A JP 2000589692A JP 2003529317 A5 JP2003529317 A5 JP 2003529317A5
- Authority
- JP
- Japan
- Prior art keywords
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- sequence
- pro866
- pcr primer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 150000001413 amino acids Chemical class 0.000 description 5
- 229920001184 polypeptide Polymers 0.000 description 4
- 108090000765 processed proteins & peptides Proteins 0.000 description 4
- 102000004196 processed proteins & peptides Human genes 0.000 description 4
- 239000000523 sample Substances 0.000 description 4
- 108091035707 Consensus sequence Proteins 0.000 description 3
- 108020004414 DNA Proteins 0.000 description 3
- 108091034117 Oligonucleotide Proteins 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 239000002299 complementary DNA Substances 0.000 description 3
- 239000002773 nucleotide Substances 0.000 description 3
- 125000003729 nucleotide group Chemical group 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 108091028043 Nucleic acid sequence Proteins 0.000 description 2
- 125000003275 alpha amino acid group Chemical group 0.000 description 2
- 238000009396 hybridization Methods 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 description 1
- 108091026890 Coding region Proteins 0.000 description 1
- 108020004705 Codon Proteins 0.000 description 1
- 102000008130 Cyclic AMP-Dependent Protein Kinases Human genes 0.000 description 1
- 108010049894 Cyclic AMP-Dependent Protein Kinases Proteins 0.000 description 1
- 102000004654 Cyclic GMP-Dependent Protein Kinases Human genes 0.000 description 1
- 108010003591 Cyclic GMP-Dependent Protein Kinases Proteins 0.000 description 1
- 229920002683 Glycosaminoglycan Polymers 0.000 description 1
- 108700026244 Open Reading Frames Proteins 0.000 description 1
- 238000012408 PCR amplification Methods 0.000 description 1
- 108010076504 Protein Sorting Signals Proteins 0.000 description 1
- 102100036427 Spondin-2 Human genes 0.000 description 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 108010074865 mindin Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical group 0.000 description 1
- 230000026731 phosphorylation Effects 0.000 description 1
- 238000006366 phosphorylation reaction Methods 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 210000005084 renal tissue Anatomy 0.000 description 1
- 230000014621 translational initiation Effects 0.000 description 1
- ODVKSTFPQDVPJZ-UHFFFAOYSA-N urinastatin Chemical compound C1C=CCCC11COC(C=2OC=CC=2)OC1 ODVKSTFPQDVPJZ-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11329698P | 1998-12-22 | 1998-12-22 | |
| US60/113,296 | 1998-12-22 | ||
| PCT/US1999/005028 WO1999046281A2 (en) | 1998-03-10 | 1999-03-08 | Novel polypeptides and nucleic acids encoding the same |
| US9905028 | 1999-03-08 | ||
| US13023299P | 1999-04-21 | 1999-04-21 | |
| US60/130,232 | 1999-04-21 | ||
| US13144599P | 1999-04-28 | 1999-04-28 | |
| US60/131,445 | 1999-04-28 | ||
| US13428799P | 1999-05-14 | 1999-05-14 | |
| US60/134,287 | 1999-05-14 | ||
| US14475899P | 1999-07-20 | 1999-07-20 | |
| US60/144,758 | 1999-07-20 | ||
| US14569899P | 1999-07-26 | 1999-07-26 | |
| US60/145,698 | 1999-07-26 | ||
| PCT/US1999/021547 WO2000015797A2 (en) | 1998-09-17 | 1999-09-15 | Compositions and methods for the treatment of immune related diseases |
| PCT/US1999/021090 WO2000015796A2 (en) | 1998-09-16 | 1999-09-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US9921547 | 1999-09-15 | ||
| US9921090 | 1999-09-15 | ||
| PCT/US1999/028565 WO2000037638A2 (en) | 1998-12-22 | 1999-12-02 | Methods and compositions for inhibiting neoplastic cell growth |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005066569A Division JP4037876B2 (ja) | 1998-12-22 | 2005-03-10 | 腫瘍性細胞成長阻害のための組成物及び方法 |
| JP2005066570A Division JP2005237383A (ja) | 1998-12-22 | 2005-03-10 | 腫瘍性細胞成長阻害のための組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003529317A JP2003529317A (ja) | 2003-10-07 |
| JP2003529317A5 true JP2003529317A5 (enExample) | 2004-12-24 |
| JP3993746B2 JP3993746B2 (ja) | 2007-10-17 |
Family
ID=27557838
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000589692A Expired - Fee Related JP3993746B2 (ja) | 1998-12-22 | 1999-12-02 | 腫瘍性細胞成長阻害のための組成物及び方法 |
| JP2005066570A Withdrawn JP2005237383A (ja) | 1998-12-22 | 2005-03-10 | 腫瘍性細胞成長阻害のための組成物及び方法 |
| JP2005066569A Expired - Lifetime JP4037876B2 (ja) | 1998-12-22 | 2005-03-10 | 腫瘍性細胞成長阻害のための組成物及び方法 |
| JP2007138468A Pending JP2007222180A (ja) | 1998-12-22 | 2007-05-24 | 腫瘍性細胞成長阻害のための組成物及び方法 |
| JP2007138469A Pending JP2007291116A (ja) | 1998-12-22 | 2007-05-24 | 腫瘍性細胞成長阻害のための組成物及び方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005066570A Withdrawn JP2005237383A (ja) | 1998-12-22 | 2005-03-10 | 腫瘍性細胞成長阻害のための組成物及び方法 |
| JP2005066569A Expired - Lifetime JP4037876B2 (ja) | 1998-12-22 | 2005-03-10 | 腫瘍性細胞成長阻害のための組成物及び方法 |
| JP2007138468A Pending JP2007222180A (ja) | 1998-12-22 | 2007-05-24 | 腫瘍性細胞成長阻害のための組成物及び方法 |
| JP2007138469A Pending JP2007291116A (ja) | 1998-12-22 | 2007-05-24 | 腫瘍性細胞成長阻害のための組成物及び方法 |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1141284A2 (enExample) |
| JP (5) | JP3993746B2 (enExample) |
| KR (1) | KR100499600B1 (enExample) |
| AT (2) | ATE432987T1 (enExample) |
| AU (1) | AU768230B2 (enExample) |
| CA (1) | CA2353799A1 (enExample) |
| DE (2) | DE69935085T2 (enExample) |
| DK (1) | DK1484338T3 (enExample) |
| ES (2) | ES2281704T3 (enExample) |
| IL (3) | IL143031A0 (enExample) |
| MX (1) | MXPA01006330A (enExample) |
| PT (1) | PT1484338E (enExample) |
| WO (1) | WO2000037638A2 (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999066041A1 (en) | 1998-06-16 | 1999-12-23 | Human Genome Sciences, Inc. | 94 human secreted proteins |
| US6392019B1 (en) | 1997-11-22 | 2002-05-21 | John Ford | Antibodies specific for EGF motif proteins |
| US6808890B2 (en) | 1999-07-28 | 2004-10-26 | Nuvelo, Inc. | Method of detecting a cancerous cell expressing EGFL6, and EGF mutif protein |
| US8088386B2 (en) | 1998-03-20 | 2012-01-03 | Genentech, Inc. | Treatment of complement-associated disorders |
| US8007798B2 (en) | 1997-11-21 | 2011-08-30 | Genentech, Inc. | Treatment of complement-associated disorders |
| US7192589B2 (en) * | 1998-09-16 | 2007-03-20 | Genentech, Inc. | Treatment of inflammatory disorders with STIgMA immunoadhesins |
| US7419663B2 (en) | 1998-03-20 | 2008-09-02 | Genentech, Inc. | Treatment of complement-associated disorders |
| JP2002504308A (ja) | 1997-11-22 | 2002-02-12 | ハイセック インコーポレイテッド | 胎児肝−脾臓のｃＤＮＡライブラリーから得られた新規ＥＧＦモチーフタンパク質 |
| EP1251139A3 (en) * | 1998-04-08 | 2002-12-18 | Genentech, Inc. | Human mindin-like protein and nucleic acids encoding it |
| US6960433B1 (en) | 1998-10-19 | 2005-11-01 | Diadexus, Inc. | Method of diagnosing, monitoring, staging, imaging and treating prostate cancer |
| AU2507700A (en) | 1999-01-15 | 2000-08-01 | Biogen, Inc. | Antagonists of tweak and of tweak receptor and their use to treat immunological disorders |
| AU768694B2 (en) * | 1999-03-08 | 2004-01-08 | Genentech Inc. | Promotion or inhibition of angiogenesis and cardiovascularization |
| AU4011300A (en) * | 1999-07-20 | 2001-02-05 | Genentech Inc. | Compositions and methods for the treatment of immune related diseases |
| MXPA02005758A (es) * | 1999-12-09 | 2002-09-18 | Sankyo Co | Metodo para evaluar un remedio o agente preventivo para hiperlipidemia. |
| PL356887A1 (en) * | 2000-01-12 | 2004-07-12 | Yale University | Nogo receptor-mediated blockade of axonal growth |
| US7119165B2 (en) | 2000-01-12 | 2006-10-10 | Yale University | Nogo receptor-mediated blockade of axonal growth |
| US6943146B2 (en) | 2000-05-08 | 2005-09-13 | Biogen Idec Ma Inc. | Method for promoting neovascularization |
| US7208151B2 (en) | 2001-09-12 | 2007-04-24 | Biogen Idec Ma Inc. | Tweak receptor agonists as anti-angiogenic agents |
| DE60141409D1 (de) | 2000-10-06 | 2010-04-08 | Biogen Idec Inc | Homologe des nogo rezeptors |
| US20020111302A1 (en) * | 2000-11-30 | 2002-08-15 | Y. Tom Tang | Novel nucleic acids and polypeptides |
| SI1997512T1 (sl) | 2002-04-09 | 2014-03-31 | Biogen Idec Ma Inc. | Postopki za zdravljenje stanj, povezanih s TWEAK-om |
| CA2391438A1 (en) * | 2002-05-01 | 2003-11-01 | Procyon Biopharma Inc. | Psp94 diagnostic reagents and assays |
| US7294704B2 (en) | 2003-08-15 | 2007-11-13 | Diadexus, Inc. | Pro108 antibody compositions and methods of use and use of Pro108 to assess cancer risk |
| DK2529619T3 (en) | 2005-02-17 | 2016-01-11 | Biogen Ma Inc | Treatment of neurological disorders |
| CA2607697C (en) | 2005-05-10 | 2015-01-06 | Biogen Idec Ma Inc. | Treating and evaluating inflammatory disorders |
| WO2006138219A2 (en) | 2005-06-13 | 2006-12-28 | Biogen Idec Ma Inc. | Methods of diagnosis / prognosis of inflammatory conditions |
| EP1904091A4 (en) | 2005-07-07 | 2009-12-23 | Univ Yale | COMPOSITIONS AND METHODS FOR SUPPRESSING THE INHIBITION OF AXON GROWTH |
| ES2551202T5 (es) | 2005-11-04 | 2018-11-30 | Genentech, Inc. | Uso de inhibidores de la vía del complemento para tratar enfermedades oculares |
| EP2010226B1 (en) * | 2006-04-07 | 2014-01-15 | The Research Foundation of State University of New York | Transcobalamin receptor polypeptides, nucleic acids, and modulators thereof, and related methods of use in modulating cell growth and treating cancer and cobalamin deficiency |
| US9044461B2 (en) | 2006-04-07 | 2015-06-02 | The Research Foundation Of State University Of New York | Transcobalamin receptor polypeptides, nucleic acids, and modulators thereof, and related methods of use in modulating cell growth and treating cancer and cobalamin deficiency |
| US7776573B2 (en) | 2006-06-01 | 2010-08-17 | Genentech, Inc. | Crystal structure of CRIg and C3b:CRIg complex |
| CN106084054A (zh) | 2006-11-02 | 2016-11-09 | 健泰科生物技术公司 | 人源化的抗‑d因子抗体 |
| AR066660A1 (es) | 2007-05-23 | 2009-09-02 | Genentech Inc | Prevencion y tratamiento de condiciones del ojo asociadas con su complemento |
| CR20170001A (es) | 2008-04-28 | 2017-08-10 | Genentech Inc | Anticuerpos anti factor d humanizados |
| LT2280996T (lt) | 2008-05-06 | 2016-12-12 | Genentech, Inc. | Subrendusio giminingumo crig variantai |
| US9120858B2 (en) | 2011-07-22 | 2015-09-01 | The Research Foundation Of State University Of New York | Antibodies to the B12-transcobalamin receptor |
| CR20160132A (es) | 2013-08-12 | 2016-08-25 | Genentech Inc | Composiciones y método para tratar condiciones asociadas con el complemento |
| SG11201608868PA (en) | 2014-05-01 | 2016-11-29 | Genentech Inc | Anti-factor d antibody variants and uses thereof |
| EP3368074A2 (en) | 2015-10-30 | 2018-09-05 | Hoffmann-La Roche AG | Anti-factor d antibodies and conjugates |
| EP3368090A1 (en) | 2015-10-30 | 2018-09-05 | H. Hoffnabb-La Roche Ag | Anti-factor d antibody variant conjugates and uses thereof |
| CN114835774B (zh) * | 2022-06-29 | 2022-09-27 | 中国农业大学 | 辣椒籽分离的寡肽msl及其在预防或治疗癌症中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ226799A (en) * | 1987-11-06 | 1991-08-27 | Oncogen | Breast cancer inhibitory factor and method for inhibiting proliferation of neoplastic cells and compositions therefor |
| US5814307A (en) * | 1989-04-10 | 1998-09-29 | Bristol-Myers Squibb Company | Method for regulating cell growth, leukocyte differentiation and tumor cell growth using Oncostatin M to stimulate synthesis of IL-6 |
| US5416192A (en) * | 1990-04-03 | 1995-05-16 | Bristol-Myers Squibb Company | Epithelins: novel cysteine-rich growth modulating proteins |
| US5028099A (en) * | 1990-08-08 | 1991-07-02 | Bertucco Leonard J | Trash recycling container |
| US6030831A (en) * | 1997-09-19 | 2000-02-29 | Genetech, Inc. | Tie ligand homologues |
| AU3661199A (en) * | 1998-04-27 | 1999-11-16 | Zymogenetics Inc. | Novel polypeptide growth factors and materials and methods for making them |
| SV1999000069A (es) * | 1998-06-02 | 2000-04-11 | Lilly Co Eli | Angiopoyetina relacionada con secuencia del gen 3 en la cicatrizacion de la cara ref. x-12261 |
| JP7039446B2 (ja) * | 2018-11-29 | 2022-03-22 | 株式会社東芝 | 電子装置 |
-
1999
- 1999-12-02 JP JP2000589692A patent/JP3993746B2/ja not_active Expired - Fee Related
- 1999-12-02 DE DE69935085T patent/DE69935085T2/de not_active Expired - Lifetime
- 1999-12-02 KR KR10-2001-7007850A patent/KR100499600B1/ko not_active Expired - Fee Related
- 1999-12-02 ES ES04007617T patent/ES2281704T3/es not_active Expired - Lifetime
- 1999-12-02 CA CA002353799A patent/CA2353799A1/en not_active Abandoned
- 1999-12-02 AT AT07001711T patent/ATE432987T1/de not_active IP Right Cessation
- 1999-12-02 DE DE69940964T patent/DE69940964D1/de not_active Expired - Lifetime
- 1999-12-02 WO PCT/US1999/028565 patent/WO2000037638A2/en not_active Ceased
- 1999-12-02 IL IL14303199A patent/IL143031A0/xx not_active IP Right Cessation
- 1999-12-02 AU AU17499/00A patent/AU768230B2/en not_active Expired
- 1999-12-02 EP EP99960644A patent/EP1141284A2/en not_active Withdrawn
- 1999-12-02 ES ES07001711T patent/ES2327785T3/es not_active Expired - Lifetime
- 1999-12-02 PT PT04007617T patent/PT1484338E/pt unknown
- 1999-12-02 AT AT04007617T patent/ATE353339T1/de active
- 1999-12-02 DK DK04007617T patent/DK1484338T3/da active
- 1999-12-02 MX MXPA01006330A patent/MXPA01006330A/es not_active Application Discontinuation
-
2005
- 2005-03-10 JP JP2005066570A patent/JP2005237383A/ja not_active Withdrawn
- 2005-03-10 JP JP2005066569A patent/JP4037876B2/ja not_active Expired - Lifetime
-
2007
- 2007-05-24 JP JP2007138468A patent/JP2007222180A/ja active Pending
- 2007-05-24 JP JP2007138469A patent/JP2007291116A/ja active Pending
- 2007-09-20 IL IL186153A patent/IL186153A0/en unknown
- 2007-09-20 IL IL186154A patent/IL186154A0/en unknown
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