JP2003524016A - Ｈｌａ結合ペプチドおよびそれらの用途 - Google Patents
Ｈｌａ結合ペプチドおよびそれらの用途Info
- Publication number
- JP2003524016A JP2003524016A JP2001562557A JP2001562557A JP2003524016A JP 2003524016 A JP2003524016 A JP 2003524016A JP 2001562557 A JP2001562557 A JP 2001562557A JP 2001562557 A JP2001562557 A JP 2001562557A JP 2003524016 A JP2003524016 A JP 2003524016A
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- peptides
- cells
- ctl
- mhc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- 229960002175 thyroglobulin Drugs 0.000 description 2
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- 235000002374 tyrosine Nutrition 0.000 description 2
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- 125000002987 valine group Chemical group [H]N([H])C([H])(C(*)=O)C([H])(C([H])([H])[H])C([H])([H])[H] 0.000 description 2
- 239000000080 wetting agent Substances 0.000 description 2
- 210000005253 yeast cell Anatomy 0.000 description 2
- GHCZTIFQWKKGSB-UHFFFAOYSA-N 2-hydroxypropane-1,2,3-tricarboxylic acid;phosphoric acid Chemical compound OP(O)(O)=O.OC(=O)CC(O)(C(O)=O)CC(O)=O GHCZTIFQWKKGSB-UHFFFAOYSA-N 0.000 description 1
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 description 1
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- 101000979735 Homo sapiens NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial Proteins 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
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- 241001631646 Papillomaviridae Species 0.000 description 1
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- 108010020346 Polyglutamic Acid Proteins 0.000 description 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 description 1
- 241000220317 Rosa Species 0.000 description 1
- 241000700584 Simplexvirus Species 0.000 description 1
- DIZPMCHEQGEION-UHFFFAOYSA-H aluminium sulfate (anhydrous) Chemical compound [Al+3].[Al+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O DIZPMCHEQGEION-UHFFFAOYSA-H 0.000 description 1
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- 229960002713 calcium chloride Drugs 0.000 description 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2000/004655 WO2001062776A1 (en) | 2000-02-23 | 2000-02-23 | Hla binding peptides and their uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2003524016A true JP2003524016A (ja) | 2003-08-12 |
Family
ID=21741082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001562557A Pending JP2003524016A (ja) | 2000-02-23 | 2000-02-23 | Ｈｌａ結合ペプチドおよびそれらの用途 |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1263775A4 (de) |
| JP (1) | JP2003524016A (de) |
| CN (1) | CN1452634A (de) |
| AU (1) | AU2000232427A1 (de) |
| BR (1) | BR0017136A (de) |
| CA (1) | CA2400215A1 (de) |
| MX (1) | MXPA02008219A (de) |
| WO (1) | WO2001062776A1 (de) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5930967B2 (ja) * | 2010-09-08 | 2016-06-08 | 学校法人 埼玉医科大学 | Ｃ型肝炎ウイルスリポソームワクチン |
| JP2019534884A (ja) * | 2016-10-07 | 2019-12-05 | エンテローム エスエー | 癌治療のための免疫原性化合物 |
| US11478538B2 (en) | 2016-10-07 | 2022-10-25 | Enterome S.A. | Immunogenic compounds for cancer therapy |
| US11712465B2 (en) | 2016-10-07 | 2023-08-01 | Enterome S.A. | Microbiota sequence variants of tumor-related antigenic epitopes |
| US12016910B2 (en) | 2018-04-11 | 2024-06-25 | Enterome S.A. | Antigenic peptides for prevention and treatment of cancer |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001000225A1 (en) * | 1999-06-29 | 2001-01-04 | Epimmune Inc. | Hla binding peptides and their uses |
| WO2001074845A2 (en) * | 2000-03-31 | 2001-10-11 | Aventis Pasteur Limited | Immunogenic peptides derived from prostate-specific membrane antigen (psma) and uses thereof |
| US20030113919A1 (en) * | 2001-08-17 | 2003-06-19 | Aventis Pasteur, Ltd. | Immunogenic targets for melanoma |
| WO2006009920A2 (en) | 2004-06-17 | 2006-01-26 | Mannkind Corporation | Epitope analogs |
| EP1842911A4 (de) * | 2005-01-25 | 2008-12-10 | Nec Corp | Hla bindende peptide, für diese codierende dna-fragmente und rekombinante vektoren |
| EP2371852A3 (de) | 2005-06-17 | 2012-08-01 | Mannkind Corporation | Epitopanaloge |
| SG162817A1 (en) * | 2005-06-17 | 2010-07-29 | Mannkind Corp | Methods and compositions.to elicit multivalent immune responses against dominant and subdominant epitopes, expressed on cancer cells and tumor stroma |
| CN1948333B (zh) * | 2005-10-14 | 2010-12-08 | 中国人民解放军第二军医大学 | 一种新的hPEBP4蛋白来源的HLA-A2限制性表位多肽及其应用 |
| EP2066689A4 (de) * | 2006-09-07 | 2010-04-28 | Univ South Florida | Hyd1-peptide als antikrebsmittel |
| TW201008574A (en) | 2008-08-19 | 2010-03-01 | Oncotherapy Science Inc | INHBB epitope peptides and vaccines containing the same |
| JP5792630B2 (ja) | 2009-01-28 | 2015-10-14 | エピミューン，インコーポレイティド | Ｐａｎ−ｄｒ結合ポリペプチドおよびその使用 |
| EP2547693B1 (de) | 2010-03-19 | 2015-03-11 | H. Lee Moffitt Cancer Center & Research Institute | Integrininteraktionshemmer zur krebsbehandlung |
| WO2015048477A1 (en) | 2013-09-27 | 2015-04-02 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Cyclic peptide conjugates and methods of use |
| MX2019005685A (es) | 2016-11-30 | 2019-09-04 | Advaxis Inc | Composiciones inmunogenicas contra mutaciones de cancer recurrentes y metodos de uso de las mismas. |
| WO2019094607A2 (en) * | 2017-11-08 | 2019-05-16 | Advaxis, Inc. | Immunogenic heteroclitic peptides from cancer-associated proteins and methods of use thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69435292D1 (de) * | 1993-03-05 | 2010-06-17 | Epimmune Inc | Verfahren zur herstellung von immunogenen hla-a2.1-bindenden peptiden |
| JP4210735B2 (ja) * | 1996-03-21 | 2009-01-21 | ファーメクサ インコーポレイテッド | Ｈｌａ―ａ２．１結合ペプチド及びその使用 |
| WO1998004284A1 (en) * | 1996-07-25 | 1998-02-05 | The Johns Hopkins University | Novel genes of kaposi's sarcoma associated herpesvirus |
| US5783567A (en) * | 1997-01-22 | 1998-07-21 | Pangaea Pharmaceuticals, Inc. | Microparticles for delivery of nucleic acid |
-
2000
- 2000-02-23 CA CA002400215A patent/CA2400215A1/en not_active Abandoned
- 2000-02-23 WO PCT/US2000/004655 patent/WO2001062776A1/en not_active Application Discontinuation
- 2000-02-23 JP JP2001562557A patent/JP2003524016A/ja active Pending
- 2000-02-23 BR BR0017136-0A patent/BR0017136A/pt not_active Application Discontinuation
- 2000-02-23 MX MXPA02008219A patent/MXPA02008219A/es unknown
- 2000-02-23 EP EP00910314A patent/EP1263775A4/de not_active Withdrawn
- 2000-02-23 CN CN00819410A patent/CN1452634A/zh active Pending
- 2000-02-23 AU AU2000232427A patent/AU2000232427A1/en not_active Abandoned
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5930967B2 (ja) * | 2010-09-08 | 2016-06-08 | 学校法人 埼玉医科大学 | Ｃ型肝炎ウイルスリポソームワクチン |
| US9814785B2 (en) | 2010-09-08 | 2017-11-14 | Saitama Medical University | Hepatitis C virus liposome vaccine |
| JP2019534884A (ja) * | 2016-10-07 | 2019-12-05 | エンテローム エスエー | 癌治療のための免疫原性化合物 |
| JP7116278B2 (ja) | 2016-10-07 | 2022-08-10 | エンテローム エスエー | 癌治療のための免疫原性化合物 |
| US11478537B2 (en) | 2016-10-07 | 2022-10-25 | Enterome S.A. | Immunogenic compounds for cancer therapy |
| US11478538B2 (en) | 2016-10-07 | 2022-10-25 | Enterome S.A. | Immunogenic compounds for cancer therapy |
| US11712465B2 (en) | 2016-10-07 | 2023-08-01 | Enterome S.A. | Microbiota sequence variants of tumor-related antigenic epitopes |
| US12016910B2 (en) | 2018-04-11 | 2024-06-25 | Enterome S.A. | Antigenic peptides for prevention and treatment of cancer |
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA02008219A (es) | 2005-06-30 |
| WO2001062776A1 (en) | 2001-08-30 |
| EP1263775A1 (de) | 2002-12-11 |
| BR0017136A (pt) | 2003-02-25 |
| AU2000232427A1 (en) | 2001-09-03 |
| EP1263775A4 (de) | 2004-10-06 |
| CN1452634A (zh) | 2003-10-29 |
| CA2400215A1 (en) | 2001-08-30 |
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