JP2003519462A5 - - Google Patents
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- Publication number
- JP2003519462A5 JP2003519462A5 JP2000526653A JP2000526653A JP2003519462A5 JP 2003519462 A5 JP2003519462 A5 JP 2003519462A5 JP 2000526653 A JP2000526653 A JP 2000526653A JP 2000526653 A JP2000526653 A JP 2000526653A JP 2003519462 A5 JP2003519462 A5 JP 2003519462A5
- Authority
- JP
- Japan
- Prior art keywords
- reporter gene
- recombinant construct
- dna molecule
- symbol placement
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 description 7
- 108020004414 DNA Proteins 0.000 description 5
- 108700008625 Reporter Genes Proteins 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 102000053602 DNA Human genes 0.000 description 4
- 239000000523 sample Substances 0.000 description 4
- 108010017842 Telomerase Proteins 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 230000003197 catalytic effect Effects 0.000 description 2
- 239000012634 fragment Substances 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 1
- 239000002299 complementary DNA Substances 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000003584 silencer Effects 0.000 description 1
- 230000009261 transgenic effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19757984.1 | 1997-12-24 | ||
| DE1997157984 DE19757984A1 (de) | 1997-12-24 | 1997-12-24 | Regulatorische DNA-Sequenzen aus der 5'-Region vom Gen der humanen katalytischen Telomerase-Untereinheit udn deren diagnostische und therapeutische Verwendung |
| PCT/EP1998/008216 WO1999033998A2 (de) | 1997-12-24 | 1998-12-22 | Regulatorische dna-sequenzen des gens der humanen katalytischen telomerase-untereinheit und deren diagnostische und therapeutische verwendung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003519462A JP2003519462A (ja) | 2003-06-24 |
| JP2003519462A5 true JP2003519462A5 (de) | 2006-01-05 |
Family
ID=7853458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000526653A Withdrawn JP2003519462A (ja) | 1997-12-24 | 1998-12-22 | ヒト触媒テロメラーゼサブユニット遺伝子の調節性ｄｎａ配列、その診断的および治療的使用 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1040195A2 (de) |
| JP (1) | JP2003519462A (de) |
| AU (1) | AU742489B2 (de) |
| CA (1) | CA2316282A1 (de) |
| DE (1) | DE19757984A1 (de) |
| WO (1) | WO1999033998A2 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6610839B1 (en) | 1997-08-14 | 2003-08-26 | Geron Corporation | Promoter for telomerase reverse transcriptase |
| US6808880B2 (en) | 1996-10-01 | 2004-10-26 | Geron Corporation | Method for detecting polynucleotides encoding telomerase |
| US6777203B1 (en) | 1997-11-19 | 2004-08-17 | Geron Corporation | Telomerase promoter driving expression of therapeutic gene sequences |
| US6093809A (en) | 1996-10-01 | 2000-07-25 | University Technology Corporation | Telomerase |
| GB2321642B8 (en) | 1996-10-01 | 2006-08-22 | Geron Corp | Human telomerase reverse transcriptase promoter |
| US6475789B1 (en) | 1996-10-01 | 2002-11-05 | University Technology Corporation | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
| US7585622B1 (en) | 1996-10-01 | 2009-09-08 | Geron Corporation | Increasing the proliferative capacity of cells using telomerase reverse transcriptase |
| US6261836B1 (en) | 1996-10-01 | 2001-07-17 | Geron Corporation | Telomerase |
| US7413864B2 (en) | 1997-04-18 | 2008-08-19 | Geron Corporation | Treating cancer using a telomerase vaccine |
| US7622549B2 (en) | 1997-04-18 | 2009-11-24 | Geron Corporation | Human telomerase reverse transcriptase polypeptides |
| US7378244B2 (en) | 1997-10-01 | 2008-05-27 | Geron Corporation | Telomerase promoters sequences for screening telomerase modulators |
| ES2220448T3 (es) * | 1999-02-04 | 2004-12-16 | Geron Corporation | Secuencias reguladoras de la transcripcion de la telomerasa transcriptasa inversa. |
| DE19947668A1 (de) * | 1999-10-04 | 2001-04-19 | Univ Eberhard Karls | Tumorspezifischer Vektor für die Gentherapie |
| DE10019195B4 (de) * | 2000-04-17 | 2006-03-09 | Heart Biosystems Gmbh | Reversible Immortalisierung |
| US6686159B2 (en) | 2000-08-24 | 2004-02-03 | Sierra Sciences, Inc. | Methods and compositions for modulating telomerase reverse transcriptase (TERT) expression |
| AU2002235141A1 (en) | 2000-11-27 | 2002-06-03 | Geron Corporation | Glycosyltransferase vectors for treating cancer |
| US6576464B2 (en) | 2000-11-27 | 2003-06-10 | Geron Corporation | Methods for providing differentiated stem cells |
| US7211435B2 (en) | 2001-06-21 | 2007-05-01 | Sierra Sciences, Inc. | Telomerase expression repressor proteins and methods of using the same |
| AU2002363231A1 (en) * | 2001-10-29 | 2003-05-12 | Baylor College Of Medicine | Human telomerase reverse transcriptase as a class-ii restricted tumor-associated antigen |
| US8163892B2 (en) | 2002-07-08 | 2012-04-24 | Oncolys Biopharma, Inc. | Oncolytic virus replicating selectively in tumor cells |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2321642B8 (en) * | 1996-10-01 | 2006-08-22 | Geron Corp | Human telomerase reverse transcriptase promoter |
-
1997
- 1997-12-24 DE DE1997157984 patent/DE19757984A1/de not_active Withdrawn
-
1998
- 1998-12-22 JP JP2000526653A patent/JP2003519462A/ja not_active Withdrawn
- 1998-12-22 EP EP98966334A patent/EP1040195A2/de not_active Withdrawn
- 1998-12-22 CA CA002316282A patent/CA2316282A1/en not_active Abandoned
- 1998-12-22 WO PCT/EP1998/008216 patent/WO1999033998A2/de not_active Application Discontinuation
- 1998-12-22 AU AU22729/99A patent/AU742489B2/en not_active Ceased
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