JP2003519462A - ヒト触媒テロメラーゼサブユニット遺伝子の調節性dna配列、その診断的および治療的使用 - Google Patents
ヒト触媒テロメラーゼサブユニット遺伝子の調節性dna配列、その診断的および治療的使用Info
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- JP2003519462A JP2003519462A JP2000526653A JP2000526653A JP2003519462A JP 2003519462 A JP2003519462 A JP 2003519462A JP 2000526653 A JP2000526653 A JP 2000526653A JP 2000526653 A JP2000526653 A JP 2000526653A JP 2003519462 A JP2003519462 A JP 2003519462A
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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DE1997157984 DE19757984A1 (de) | 1997-12-24 | 1997-12-24 | Regulatorische DNA-Sequenzen aus der 5'-Region vom Gen der humanen katalytischen Telomerase-Untereinheit udn deren diagnostische und therapeutische Verwendung |
DE19757984.1 | 1997-12-24 | ||
PCT/EP1998/008216 WO1999033998A2 (de) | 1997-12-24 | 1998-12-22 | Regulatorische dna-sequenzen des gens der humanen katalytischen telomerase-untereinheit und deren diagnostische und therapeutische verwendung |
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JP2003519462A true JP2003519462A (ja) | 2003-06-24 |
JP2003519462A5 JP2003519462A5 (de) | 2006-01-05 |
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JP2000526653A Withdrawn JP2003519462A (ja) | 1997-12-24 | 1998-12-22 | ヒト触媒テロメラーゼサブユニット遺伝子の調節性dna配列、その診断的および治療的使用 |
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EP (1) | EP1040195A2 (de) |
JP (1) | JP2003519462A (de) |
AU (1) | AU742489B2 (de) |
CA (1) | CA2316282A1 (de) |
DE (1) | DE19757984A1 (de) |
WO (1) | WO1999033998A2 (de) |
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US6808880B2 (en) | 1996-10-01 | 2004-10-26 | Geron Corporation | Method for detecting polynucleotides encoding telomerase |
US6261836B1 (en) | 1996-10-01 | 2001-07-17 | Geron Corporation | Telomerase |
US6093809A (en) | 1996-10-01 | 2000-07-25 | University Technology Corporation | Telomerase |
US6610839B1 (en) | 1997-08-14 | 2003-08-26 | Geron Corporation | Promoter for telomerase reverse transcriptase |
WO1998014592A2 (en) | 1996-10-01 | 1998-04-09 | Geron Corporation | Telomerase reverse transcriptase |
US6777203B1 (en) | 1997-11-19 | 2004-08-17 | Geron Corporation | Telomerase promoter driving expression of therapeutic gene sequences |
US7585622B1 (en) | 1996-10-01 | 2009-09-08 | Geron Corporation | Increasing the proliferative capacity of cells using telomerase reverse transcriptase |
US6475789B1 (en) | 1996-10-01 | 2002-11-05 | University Technology Corporation | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
US7413864B2 (en) | 1997-04-18 | 2008-08-19 | Geron Corporation | Treating cancer using a telomerase vaccine |
US7622549B2 (en) | 1997-04-18 | 2009-11-24 | Geron Corporation | Human telomerase reverse transcriptase polypeptides |
US7378244B2 (en) | 1997-10-01 | 2008-05-27 | Geron Corporation | Telomerase promoters sequences for screening telomerase modulators |
EP1147181B1 (de) * | 1999-02-04 | 2004-05-12 | Geron Corporation | Replikativer virus gesteuert von dem promotor der reversen telomerase transkriptase zur behandlung von krebs |
DE19947668A1 (de) | 1999-10-04 | 2001-04-19 | Univ Eberhard Karls | Tumorspezifischer Vektor für die Gentherapie |
DE10019195B4 (de) * | 2000-04-17 | 2006-03-09 | Heart Biosystems Gmbh | Reversible Immortalisierung |
US6686159B2 (en) | 2000-08-24 | 2004-02-03 | Sierra Sciences, Inc. | Methods and compositions for modulating telomerase reverse transcriptase (TERT) expression |
US6713055B2 (en) | 2000-11-27 | 2004-03-30 | Geron Corporation | Glycosyltransferase vectors for treating cancer |
US6576464B2 (en) | 2000-11-27 | 2003-06-10 | Geron Corporation | Methods for providing differentiated stem cells |
WO2003000916A2 (en) | 2001-06-21 | 2003-01-03 | Sierra Sciences, Inc. | Telomerase expression repressor proteins and methods of using the same |
AU2002363231A1 (en) * | 2001-10-29 | 2003-05-12 | Baylor College Of Medicine | Human telomerase reverse transcriptase as a class-ii restricted tumor-associated antigen |
US8163892B2 (en) | 2002-07-08 | 2012-04-24 | Oncolys Biopharma, Inc. | Oncolytic virus replicating selectively in tumor cells |
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WO1998014592A2 (en) * | 1996-10-01 | 1998-04-09 | Geron Corporation | Telomerase reverse transcriptase |
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AU2272999A (en) | 1999-07-19 |
WO1999033998A3 (de) | 1999-08-19 |
CA2316282A1 (en) | 1999-07-08 |
AU742489B2 (en) | 2002-01-03 |
DE19757984A1 (de) | 1999-07-01 |
WO1999033998A2 (de) | 1999-07-08 |
EP1040195A2 (de) | 2000-10-04 |
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