JP2003517015A - ヘリコバクターピロリ結合性新規物質およびその用途 - Google Patents

ヘリコバクターピロリ結合性新規物質およびその用途

Info

Publication number
JP2003517015A
JP2003517015A JP2001544888A JP2001544888A JP2003517015A JP 2003517015 A JP2003517015 A JP 2003517015A JP 2001544888 A JP2001544888 A JP 2001544888A JP 2001544888 A JP2001544888 A JP 2001544888A JP 2003517015 A JP2003517015 A JP 2003517015A
Authority
JP
Japan
Prior art keywords
helicobacter pylori
binding
pharmaceutical composition
binding substance
substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001544888A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003517015A5 (cg-RX-API-DMAC7.html
Inventor
カールソン，カール−アンデシュ
レオナードソン，イレネ
テネベリ，スサン
オングストロム，ヨーナス
Original Assignee
アープラス シエンセ インベステ アーベー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アープラス シエンセ インベステ アーベー filed Critical アープラス シエンセ インベステ アーベー
Publication of JP2003517015A publication Critical patent/JP2003517015A/ja
Publication of JP2003517015A5 publication Critical patent/JP2003517015A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2001544888A 1999-12-15 2000-12-15 ヘリコバクターピロリ結合性新規物質およびその用途 Pending JP2003517015A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9904581A SE9904581D0 (sv) 1999-12-15 1999-12-15 A novel helicobacter pylori-binding substance and use thereof
SE9904581-7 1999-12-15
PCT/SE2000/002567 WO2001043751A1 (en) 1999-12-15 2000-12-15 Novel helicobacter pylori-binding substances and use thereof

Publications (2)

Publication Number Publication Date
JP2003517015A true JP2003517015A (ja) 2003-05-20
JP2003517015A5 JP2003517015A5 (cg-RX-API-DMAC7.html) 2008-02-14

Family

ID=20418126

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001544888A Pending JP2003517015A (ja) 1999-12-15 2000-12-15 ヘリコバクターピロリ結合性新規物質およびその用途

Country Status (18)

Country Link
US (1) US20040086514A1 (cg-RX-API-DMAC7.html)
EP (1) EP1237558A1 (cg-RX-API-DMAC7.html)
JP (1) JP2003517015A (cg-RX-API-DMAC7.html)
CN (1) CN100389773C (cg-RX-API-DMAC7.html)
AU (1) AU783876B2 (cg-RX-API-DMAC7.html)
CA (1) CA2392766A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ20021989A3 (cg-RX-API-DMAC7.html)
EE (1) EE200200312A (cg-RX-API-DMAC7.html)
HU (1) HUP0204243A3 (cg-RX-API-DMAC7.html)
IL (1) IL150247A0 (cg-RX-API-DMAC7.html)
NO (1) NO20022890L (cg-RX-API-DMAC7.html)
NZ (1) NZ520111A (cg-RX-API-DMAC7.html)
PL (1) PL356329A1 (cg-RX-API-DMAC7.html)
RU (1) RU2283115C2 (cg-RX-API-DMAC7.html)
SE (1) SE9904581D0 (cg-RX-API-DMAC7.html)
SK (1) SK8152002A3 (cg-RX-API-DMAC7.html)
WO (1) WO2001043751A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200204251B (cg-RX-API-DMAC7.html)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007057334A (ja) * 2005-08-23 2007-03-08 Nagasaki Univ ヘリコバクター・ピロリの空胞化毒素の検出試薬および検出方法
JP2008120789A (ja) * 2006-10-18 2008-05-29 Asahi Kasei Chemicals Corp ピロリ菌の抑制剤または静菌剤
WO2010041746A1 (ja) * 2008-10-10 2010-04-15 財団法人野口研究所 ピロリ菌増殖抑制剤
US8575117B2 (en) 2007-01-12 2013-11-05 The Noguchi Institute Proliferation inhibitor of helicobacter pylori including alpha-n-acetyl-glucosaminyl bond-containing monosaccharide derivatives

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9904581D0 (sv) * 1999-12-15 1999-12-15 A & Science Invest Ab A novel helicobacter pylori-binding substance and use thereof
FI20010118L (fi) * 2001-01-19 2002-07-20 Carbion Oy Uudet helicobacter pylori reseptorit ja niiden käyttö
EP1411952B1 (en) * 2001-06-29 2009-04-22 Glykos Finland Oy Use of at least one glycoinhibitor substance against infectious diseases
FI20011403L (fi) * 2001-06-29 2002-12-30 Carbion Oy Menetelmä ja koostumukset vatsan sairauksien hoitoon
AU2003201619A1 (en) * 2002-01-18 2003-07-30 Biotie Therapies Corporation Novel binding epitopes for helicobacter pylori and use thereof
EP1332759B1 (en) * 2002-02-04 2005-09-28 Kyowa Hakko Kogyo Co., Ltd. Pharmaceutical and nutritional compositions containing a di- or oligosaccharide as insulin secretion promoter
EP2272522B1 (en) * 2002-06-28 2017-09-06 Nestec S.A. Therapeutic compositions for use in prophylaxis or treatment of diarrheas
FI20021989A0 (fi) * 2002-11-06 2002-11-06 Halina Miller-Podraza Korkean affiniteetin Helicobacter pylori-reseptorit ja niiden käyttö
EP1866071A4 (en) * 2005-03-03 2013-04-24 Univ Indiana Res & Tech Corp PERMETHYLATION OF OLIGOSACCHARIDES
FR2906808B1 (fr) * 2006-10-10 2012-10-05 Univ Nantes Utilisation d'anticorps monoclonaux specifiques de la forme o-acetylee du ganglioside gd2 dans le traitement de certains cancers
EP2060257A1 (en) 2007-11-08 2009-05-20 Nestec S.A. Prevention and treatment of secondary infections following viral infection
GB0817908D0 (en) * 2008-10-01 2008-11-05 Univ Ghent Blood group a/b/h determinant on type 1 core glycosphinglipids chain as recognition point for the fedf protein of f18-fimbriated enterotoxigenic
EP2844301A2 (en) * 2012-05-04 2015-03-11 Ineb-instituto de Engenharia Biomédica Microspheres for treating helicobacter pylori infections

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WO1995029927A2 (en) * 1994-05-02 1995-11-09 Biomira, Inc. Process for preparation of glycosides of tumor-associated carbohydrate antigens
JPH1045602A (ja) * 1996-07-31 1998-02-17 Motoyasu Murakami ヘリコバクター・ピロリ接着阻害剤またはインターロイキン−８産生阻害剤
JPH11292788A (ja) * 1998-04-01 1999-10-26 Snow Brand Milk Prod Co Ltd ピロリ菌感染防御剤

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WO2000070060A1 (en) * 1999-05-18 2000-11-23 University Of Iowa Research Foundation Production of complex carbohydrates
AUPQ275799A0 (en) * 1999-09-10 1999-10-07 Luminis Pty Limited Recombinant bacterium expressing an oligosaccharide receptor mimic
FI19992070A7 (fi) * 1999-09-28 2001-03-29 Carbion Oy Uudet fukosyloidut oligosakkaridit ja menetelmä niiden valmistamiseksi
SE9904581D0 (sv) * 1999-12-15 1999-12-15 A & Science Invest Ab A novel helicobacter pylori-binding substance and use thereof
FI20010118L (fi) * 2001-01-19 2002-07-20 Carbion Oy Uudet helicobacter pylori reseptorit ja niiden käyttö
EP1417965A1 (en) * 2002-11-07 2004-05-12 Vereniging Voor Christelijk Wetenschappelijk Onderwijs C-type lectin binding molecules, identification and uses thereof
ES2344114T3 (es) * 2004-05-11 2010-08-18 De Staat Der Nederlanden, Vert. Door De Minister Van Vws Lipooligosacaridos de neisseria meningitidis igtb como adyuvante.
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Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995029927A2 (en) * 1994-05-02 1995-11-09 Biomira, Inc. Process for preparation of glycosides of tumor-associated carbohydrate antigens
JPH1045602A (ja) * 1996-07-31 1998-02-17 Motoyasu Murakami ヘリコバクター・ピロリ接着阻害剤またはインターロイキン−８産生阻害剤
JPH11292788A (ja) * 1998-04-01 1999-10-26 Snow Brand Milk Prod Co Ltd ピロリ菌感染防御剤

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007057334A (ja) * 2005-08-23 2007-03-08 Nagasaki Univ ヘリコバクター・ピロリの空胞化毒素の検出試薬および検出方法
JP2008120789A (ja) * 2006-10-18 2008-05-29 Asahi Kasei Chemicals Corp ピロリ菌の抑制剤または静菌剤
US8575117B2 (en) 2007-01-12 2013-11-05 The Noguchi Institute Proliferation inhibitor of helicobacter pylori including alpha-n-acetyl-glucosaminyl bond-containing monosaccharide derivatives
WO2010041746A1 (ja) * 2008-10-10 2010-04-15 財団法人野口研究所 ピロリ菌増殖抑制剤
US8859511B2 (en) 2008-10-10 2014-10-14 The Noguchi Institute Proliferation inhibitor of Helicobacter pylori bacteria

Also Published As

Publication number Publication date
HUP0204243A3 (en) 2003-08-28
US20040086514A1 (en) 2004-05-06
ZA200204251B (en) 2003-05-28
NO20022890L (no) 2002-08-15
CN1411376A (zh) 2003-04-16
AU2418801A (en) 2001-06-25
SE9904581D0 (sv) 1999-12-15
SK8152002A3 (en) 2002-11-06
NO20022890D0 (no) 2002-06-17
NZ520111A (en) 2004-08-27
CN100389773C (zh) 2008-05-28
CZ20021989A3 (cs) 2002-10-16
WO2001043751A1 (en) 2001-06-21
EP1237558A1 (en) 2002-09-11
RU2283115C2 (ru) 2006-09-10
CA2392766A1 (en) 2001-06-21
AU783876B2 (en) 2005-12-15
HUP0204243A2 (hu) 2003-03-28
EE200200312A (et) 2003-06-16
RU2002118703A (ru) 2004-02-20
PL356329A1 (en) 2004-06-28
IL150247A0 (en) 2002-12-01

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