JP2003509031A5 - - Google Patents
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- Publication number
- JP2003509031A5 JP2003509031A5 JP2001522835A JP2001522835A JP2003509031A5 JP 2003509031 A5 JP2003509031 A5 JP 2003509031A5 JP 2001522835 A JP2001522835 A JP 2001522835A JP 2001522835 A JP2001522835 A JP 2001522835A JP 2003509031 A5 JP2003509031 A5 JP 2003509031A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- cell
- differentiated
- nuclei
- pig
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cells Anatomy 0.000 description 36
- 241000282898 Sus scrofa Species 0.000 description 14
- 210000004940 Nucleus Anatomy 0.000 description 13
- 210000003855 Cell Nucleus Anatomy 0.000 description 11
- 210000000287 oocyte Anatomy 0.000 description 11
- 229920003013 deoxyribonucleic acid Polymers 0.000 description 4
- 230000001605 fetal Effects 0.000 description 4
- 230000002062 proliferating Effects 0.000 description 4
- 210000001161 Embryo, Mammalian Anatomy 0.000 description 3
- 230000003213 activating Effects 0.000 description 3
- 239000010807 litter Substances 0.000 description 3
- 241000124008 Mammalia Species 0.000 description 2
- 108091006028 chimera Proteins 0.000 description 2
- 230000035772 mutation Effects 0.000 description 2
- 210000001519 tissues Anatomy 0.000 description 2
- 210000000625 Blastula Anatomy 0.000 description 1
- 210000003981 Ectoderm Anatomy 0.000 description 1
- 210000001900 Endoderm Anatomy 0.000 description 1
- 210000003754 Fetus Anatomy 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 229920002957 Naked DNA Polymers 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 238000010367 cloning Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 238000004520 electroporation Methods 0.000 description 1
- 210000002308 embryonic cell Anatomy 0.000 description 1
- 210000002257 embryonic structures Anatomy 0.000 description 1
- 230000007159 enucleation Effects 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 230000002068 genetic Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 210000004962 mammalian cells Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000520 microinjection Methods 0.000 description 1
- 230000012223 nuclear import Effects 0.000 description 1
- 210000000056 organs Anatomy 0.000 description 1
- 230000000644 propagated Effects 0.000 description 1
- 210000001082 somatic cell Anatomy 0.000 description 1
- 239000003104 tissue culture media Substances 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 230000003612 virological Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/394,902 US7291764B1 (en) | 1997-01-10 | 1999-09-13 | Cloning pigs using non-quiescent differentiated donor cells or nuclei |
| US09/394,902 | 1999-09-13 | ||
| PCT/US2000/024958 WO2001019181A1 (en) | 1999-09-13 | 2000-09-13 | Cloning pigs using donor cells or nuclei from differentiated cells and production of pluripotent porcine. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003509031A JP2003509031A (ja) | 2003-03-11 |
| JP2003509031A5 true JP2003509031A5 (zh) | 2007-10-11 |
Family
ID=23560867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001522835A Pending JP2003509031A (ja) | 1999-09-13 | 2000-09-13 | ドナー細胞又は分化細胞からの核を使用する豚のクローニング並びに多能性豚の産生 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1241931A4 (zh) |
| JP (1) | JP2003509031A (zh) |
| CN (1) | CN1377225A (zh) |
| AU (1) | AU7372500A (zh) |
| BR (1) | BR0013959A (zh) |
| CA (1) | CA2381124A1 (zh) |
| IL (1) | IL148508A0 (zh) |
| MX (1) | MXPA02002653A (zh) |
| WO (1) | WO2001019181A1 (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7519660B2 (ja) | 2016-06-14 | 2024-07-22 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004275074A (ja) * | 2003-03-14 | 2004-10-07 | Nipro Corp | 動物胚における正常性のスクリーニング方法 |
| CN100404675C (zh) * | 2006-02-22 | 2008-07-23 | 李宁 | 一种生产体细胞克隆猪的方法 |
| CA2717251A1 (en) * | 2007-03-07 | 2008-09-12 | Aarhus Universitet | Pig model for breast cancer, mitochondria related protein folding disorders and/or epidermolysis bullosa simplex |
| CN116059378A (zh) | 2014-12-10 | 2023-05-05 | 明尼苏达大学董事会 | 用于治疗疾病的遗传修饰的细胞、组织和器官 |
| WO2016140353A1 (ja) * | 2015-03-04 | 2016-09-09 | 株式会社 医療実験用大動物供給事業準備会社 | 安定した表現型を示す疾患モデルブタおよびその作製方法 |
| CN111349615B (zh) * | 2018-12-24 | 2024-08-13 | 上海细胞治疗集团股份有限公司 | 制备过表达外源基因的细胞的方法 |
| CN115305260B (zh) * | 2021-11-30 | 2023-09-22 | 海南大学 | 一种金鲳鱼受精卵的显微注射方法及应用 |
| CN116640804A (zh) * | 2023-04-20 | 2023-08-25 | 云南农业大学 | 一种基于体细胞核移植技术构建三倍体猪的方法 |
| CN117044679B (zh) * | 2023-10-13 | 2024-01-19 | 成都铁骑力士饲料有限公司 | 一种血清fas在川藏黑猪s05系瘦肉型猪选育中的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1149898A2 (en) * | 1993-12-23 | 2001-10-31 | Infigen, Inc. | Embryonic stem cells as nuclear donors and nuclear transfer techniques to produce chimeric and transgenic animals |
| US5905042A (en) * | 1996-04-01 | 1999-05-18 | University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus | Cultured inner cell mass cell lines derived from bovine or porcine embryos |
| US6235969B1 (en) * | 1997-01-10 | 2001-05-22 | University Of Massachusetts | Cloning pigs using donor nuclei from non-quiescent differentiated cells |
| US5945577A (en) * | 1997-01-10 | 1999-08-31 | University Of Massachusetts As Represented By Its Amherst Campus | Cloning using donor nuclei from proliferating somatic cells |
-
2000
- 2000-09-13 IL IL14850800A patent/IL148508A0/xx unknown
- 2000-09-13 AU AU73725/00A patent/AU7372500A/en not_active Abandoned
- 2000-09-13 MX MXPA02002653A patent/MXPA02002653A/es not_active Application Discontinuation
- 2000-09-13 BR BR0013959-9A patent/BR0013959A/pt not_active Application Discontinuation
- 2000-09-13 CN CN00813714A patent/CN1377225A/zh active Pending
- 2000-09-13 JP JP2001522835A patent/JP2003509031A/ja active Pending
- 2000-09-13 WO PCT/US2000/024958 patent/WO2001019181A1/en active Application Filing
- 2000-09-13 EP EP00961827A patent/EP1241931A4/en not_active Withdrawn
- 2000-09-13 CA CA002381124A patent/CA2381124A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7519660B2 (ja) | 2016-06-14 | 2024-07-22 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
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