JP2003508730A - 電荷中性共役ポリマーを用いるバイオセンサー - Google Patents

電荷中性共役ポリマーを用いるバイオセンサー

Info

Publication number
JP2003508730A
JP2003508730A JP2001503529A JP2001503529A JP2003508730A JP 2003508730 A JP2003508730 A JP 2003508730A JP 2001503529 A JP2001503529 A JP 2001503529A JP 2001503529 A JP2001503529 A JP 2001503529A JP 2003508730 A JP2003508730 A JP 2003508730A
Authority
JP
Japan
Prior art keywords
charge
conjugated polymer
electrode
neutral conjugated
probe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001503529A
Other languages
English (en)
Japanese (ja)
Inventor
リ・チャンミン
シ・ソン
ビ−エン・チョーン
ジョージ・マラカス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Motorola Solutions Inc
Original Assignee
Motorola Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Motorola Inc filed Critical Motorola Inc
Publication of JP2003508730A publication Critical patent/JP2003508730A/ja
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00614—Delimitation of the attachment areas
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00623—Immobilisation or binding
    • B01J2219/00626—Covalent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632—Introduction of reactive groups to the surface
    • B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00653—Making arrays on substantially continuous surfaces the compounds being bound to electrodes embedded in or on the solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00709—Type of synthesis
    • B01J2219/00713—Electrochemical synthesis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
JP2001503529A 1999-06-10 2000-06-09 電荷中性共役ポリマーを用いるバイオセンサー Pending JP2003508730A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13843799P 1999-06-10 1999-06-10
US60/138,437 1999-06-10
PCT/US2000/015832 WO2000077523A1 (fr) 1999-06-10 2000-06-09 Biocapteurs utilisant des polymeres conjugues a charge neutre

Publications (1)

Publication Number Publication Date
JP2003508730A true JP2003508730A (ja) 2003-03-04

Family

ID=22482012

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001503529A Pending JP2003508730A (ja) 1999-06-10 2000-06-09 電荷中性共役ポリマーを用いるバイオセンサー

Country Status (5)

Country Link
EP (1) EP1190253A1 (fr)
JP (1) JP2003508730A (fr)
AU (1) AU776997B2 (fr)
CA (1) CA2376532A1 (fr)
WO (1) WO2000077523A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007161717A (ja) * 2005-12-16 2007-06-28 Sungkyunkwan Univ Foundation For Corporate Collaboration ポリジアセチレン超分子体とリガンド検出方法。
JP2015508506A (ja) * 2012-01-27 2015-03-19 ユニバーシティ オブ テネシー リサーチ ファウンデーション 交流動電によるバイオマーカーの検出のための方法および装置

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19938138C2 (de) * 1999-08-16 2003-02-13 November Ag Molekulare Medizin Verfahren und Vorrichtung zur Identifikation einer Biopolymersequenz auf Festkörperoberflächen
US6824669B1 (en) * 2000-02-17 2004-11-30 Motorola, Inc. Protein and peptide sensors using electrical detection methods
DE10022750A1 (de) * 2000-05-10 2001-11-22 Wolfgang Schuhmann Verfahren zur Immobilisierung von Erkennungskomponenten
US7063978B2 (en) 2001-11-01 2006-06-20 3M Innovative Properties Company Coated film laminate having an electrically conductive surface
DE10228260A1 (de) * 2002-06-25 2004-01-22 Bayer Ag Methode und Vorrichtung zum impedimetrischen Nachweis eines oder mehrerer Analyten in einer Probe
US7598344B2 (en) * 2002-09-04 2009-10-06 Board Of Regents, The University Of Texas System Composition, method and use of bi-functional biomaterials
AU2003285301A1 (en) * 2002-10-28 2004-05-13 Apibio Sas Biochip and method for processing a plurality of fiochips
WO2004044570A1 (fr) * 2002-11-14 2004-05-27 Toyama Prefecture Procede de detection d'hybridation
FR2849038B1 (fr) 2002-12-19 2005-03-11 Apibio Nouveaux pyrroles substitues avec des oligonucleotides, polymeres electroactifs et leurs utilisations
DE10311315A1 (de) 2003-03-14 2004-09-30 Apibio Sas Verfahren und Vorrichtung zur Detektion von Biomolekülen
DE10319155B4 (de) * 2003-04-29 2008-02-14 Bruker Daltonik Gmbh Elektrisch auslesbare Bindungen von Analytmolekülen an immobilisierten Sondenmolekülen
WO2005078118A1 (fr) 2004-02-06 2005-08-25 Bayer Healthcare Llc Especes oxydables servant de reference interne a des biocapteurs, et procede d'utilisation
US8097134B2 (en) 2004-04-01 2012-01-17 Nanyang Technological University Addressable chem/bio chip array
KR101577176B1 (ko) 2005-09-30 2015-12-14 바이엘 헬스케어 엘엘씨 게이트형 전압 전류 측정 분석물 결정 방법
ES2825036T3 (es) 2006-10-24 2021-05-14 Ascensia Diabetes Care Holdings Ag Amperometría de decaimiento transitorio
WO2009076302A1 (fr) 2007-12-10 2009-06-18 Bayer Healthcare Llc Marqueurs de contrôle pour la détection automatique d'une solution de contrôle et procédés d'utilisation
FR2962445B1 (fr) 2010-07-08 2013-06-28 Biomerieux Sa Procede de detection et d'identification directe d'un microorganisme dans un echantillon biologique dilue dans un bouillon d'enrichissement
CN102520187B (zh) * 2011-11-23 2014-06-18 江南大学 一种基于聚苯胺纳米金复合膜免疫传感器的制备方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2703359B1 (fr) * 1993-03-31 1995-06-23 Cis Bio Int Copolymère nucléotide(s)/polymère conducteur électronique ; son procédé de préparation et son utilisation .
FR2720832A1 (fr) * 1994-04-22 1995-12-08 Francis Garnier Electrodes et membranes électroactives à base de peptides bioactifs, pour la reconnaissance, l'extraction ou le relargage d'espèces biologiquement actives.
DE19507413A1 (de) * 1994-05-06 1995-11-09 Bayer Ag Leitfähige Beschichtungen
KR0162864B1 (ko) * 1995-01-19 1999-01-15 김은영 가용 전기전도성 폴리피롤의 제조방법

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007161717A (ja) * 2005-12-16 2007-06-28 Sungkyunkwan Univ Foundation For Corporate Collaboration ポリジアセチレン超分子体とリガンド検出方法。
JP2015508506A (ja) * 2012-01-27 2015-03-19 ユニバーシティ オブ テネシー リサーチ ファウンデーション 交流動電によるバイオマーカーの検出のための方法および装置

Also Published As

Publication number Publication date
EP1190253A1 (fr) 2002-03-27
AU5475700A (en) 2001-01-02
AU776997B2 (en) 2004-09-30
CA2376532A1 (fr) 2000-12-21
WO2000077523A1 (fr) 2000-12-21

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