JP2003508343A - がんの予防、診断、予後、及び治療の手段としての末梢型ベンゾジアゼピン受容体 - Google Patents

がんの予防、診断、予後、及び治療の手段としての末梢型ベンゾジアゼピン受容体

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Publication number
JP2003508343A
JP2003508343A JP2000538235A JP2000538235A JP2003508343A JP 2003508343 A JP2003508343 A JP 2003508343A JP 2000538235 A JP2000538235 A JP 2000538235A JP 2000538235 A JP2000538235 A JP 2000538235A JP 2003508343 A JP2003508343 A JP 2003508343A
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Prior art keywords
pbr
cell
tumor
cells
rna
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Pending
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JP2000538235A
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English (en)
Japanese (ja)
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JP2003508343A5 (https=
Inventor
ヴァシリオス パパドポウロス
マーティン カルティー
Original Assignee
ジョージタウン ユニヴァーシティー メディカル センター
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Publication of JP2003508343A publication Critical patent/JP2003508343A/ja
Publication of JP2003508343A5 publication Critical patent/JP2003508343A5/ja
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57515—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2000538235A 1998-03-25 1999-03-25 がんの予防、診断、予後、及び治療の手段としての末梢型ベンゾジアゼピン受容体 Pending JP2003508343A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/047,652 US7267977B2 (en) 1998-03-25 1998-03-25 Peripheral-type benzodiazepine receptor: a tool for detection, diagnosis, prognosis, and treatment of cancer
US09/047,652 1998-03-25
PCT/US1999/006515 WO1999049316A2 (en) 1998-03-25 1999-03-25 Peripheral-type benzodiazepine receptor: a tool for detection, diagnosis, prognosis, and treatment of cancer

Publications (2)

Publication Number Publication Date
JP2003508343A true JP2003508343A (ja) 2003-03-04
JP2003508343A5 JP2003508343A5 (https=) 2006-05-25

Family

ID=21950183

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000538235A Pending JP2003508343A (ja) 1998-03-25 1999-03-25 がんの予防、診断、予後、及び治療の手段としての末梢型ベンゾジアゼピン受容体

Country Status (6)

Country Link
US (1) US7267977B2 (https=)
EP (2) EP1063997A2 (https=)
JP (1) JP2003508343A (https=)
AU (1) AU3364899A (https=)
CA (1) CA2325445A1 (https=)
WO (1) WO1999049316A2 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7267977B2 (en) 1998-03-25 2007-09-11 Georgetown University Peripheral-type benzodiazepine receptor: a tool for detection, diagnosis, prognosis, and treatment of cancer
US7056694B1 (en) 1998-08-11 2006-06-06 Georgetown University DNA encoding peripheral-type benzodiazipine receptor associated protein 7 and applications or methods of use
JP2004500009A (ja) * 1998-08-11 2004-01-08 ジョージタウン・ユニバーシティ・メディカル・センター 周辺型ベンゾジアゼピン受容体関連タンパク質、クローン化発現及びその使用方法
KR20020060154A (ko) * 1999-08-12 2002-07-16 다푸르 가브리에 은행 추출물의 용도
US7078434B1 (en) 1999-08-12 2006-07-18 Societe De Conseils De Recherches Et D'applications Scientifiques Sas Use of Ginkgo extract
WO2001051922A2 (en) * 2000-01-14 2001-07-19 Mitokor Identification of peripheral benzodiazepine receptor binding agents
DE10234201A1 (de) * 2002-07-26 2004-02-12 Freie Universität Berlin Verwendung einer Zusammenstellung zur Behandlung neuroendokriner und gastrointestinaler Tumoren
JP4362457B2 (ja) 2005-04-26 2009-11-11 独立行政法人科学技術振興機構 神経因性疼痛治療剤
WO2007089880A2 (en) * 2006-01-31 2007-08-09 Georgetown University Method to detect breast cancer cells
WO2008001357A2 (en) * 2006-06-26 2008-01-03 Technion Research & Development Foundation Ltd. Methods and kits for diagnosing cancer
US9075060B2 (en) 2009-06-16 2015-07-07 Technion Research & Development Foundation Limited Methods for diagnosing oral or oral-pharyngeal cancer
JP2016516399A (ja) * 2013-03-13 2016-06-09 オーストラリアン ニュークリア サイエンス アンド テクノロジー オーガニゼーション 非機能性ｔｓｐｏ遺伝子を有するトランスジェニック非ヒト生物
US12234701B2 (en) 2022-09-12 2025-02-25 Saudi Arabian Oil Company Tubing hangers and related methods of isolating a tubing
US12188328B2 (en) 2023-05-15 2025-01-07 Saudi Arabian Oil Company Wellbore back pressure valve with pressure gauge
US12442257B2 (en) 2023-05-23 2025-10-14 Saudi Arabian Oil Company Completing and working over a wellbore

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5407799A (en) * 1989-09-14 1995-04-18 Associated Universities, Inc. Method for high-volume sequencing of nucleic acids: random and directed priming with libraries of oligonucleotides
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
US5663062A (en) * 1992-04-03 1997-09-02 Stratagene Oligonucleotide libraries useful for producing primers
US5585479A (en) * 1992-07-24 1996-12-17 The United States Of America As Represented By The Secretary Of The Navy Antisense oligonucleotides directed against human ELAM-I RNA
CA2151585A1 (en) * 1992-12-14 1994-06-23 Start Technology Partnership Administration of oligonucleotides antisense to dopamine receptor mrna for diagnosis and treatment of neurological pathologies
US5948676A (en) * 1996-10-10 1999-09-07 The Trustees Of Columbia University In The City Of New York Immediate early protein from Kaposi's sarcoma-associated herpesvirus, DNA encoding same and uses thereof
US7267977B2 (en) 1998-03-25 2007-09-11 Georgetown University Peripheral-type benzodiazepine receptor: a tool for detection, diagnosis, prognosis, and treatment of cancer
WO2000001821A2 (en) 1998-07-02 2000-01-13 Incyte Pharmaceuticals, Inc. Neurotransmission associated proteins
JP2004500009A (ja) * 1998-08-11 2004-01-08 ジョージタウン・ユニバーシティ・メディカル・センター 周辺型ベンゾジアゼピン受容体関連タンパク質、クローン化発現及びその使用方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN5001012289, ＨＡＲＤＷＩＣＫ Ｍ, ＡＭＥＲＩＣＡＮ ＡＳＳＯＣＩＡＴＩＯＮ ＦＯＲ ＣＡＮＣＥＲ ＲＥＳＥＡＲＣＨ ＡＮＮＵＡＬ ＭＥＥＴＩＮＧ ８８ＴＨ, 19971231, Ｖ３８ １９９７年発行, Ｐ２３３ *

Also Published As

Publication number Publication date
US20030157095A1 (en) 2003-08-21
US7267977B2 (en) 2007-09-11
AU3364899A (en) 1999-10-18
EP1757295A1 (en) 2007-02-28
EP1063997A2 (en) 2001-01-03
WO1999049316A2 (en) 1999-09-30
CA2325445A1 (en) 1999-09-30
WO1999049316A3 (en) 1999-11-11

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