JP2003505075A - 新規線維芽細胞増殖因子およびこれをコードする核酸 - Google Patents

新規線維芽細胞増殖因子およびこれをコードする核酸

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Publication number
JP2003505075A
JP2003505075A JP2001512864A JP2001512864A JP2003505075A JP 2003505075 A JP2003505075 A JP 2003505075A JP 2001512864 A JP2001512864 A JP 2001512864A JP 2001512864 A JP2001512864 A JP 2001512864A JP 2003505075 A JP2003505075 A JP 2003505075A
Authority
JP
Japan
Prior art keywords
fgf
polypeptide
nucleic acid
protein
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001512864A
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English (en)
Japanese (ja)
Other versions
JP2003505075A5 (enExample
Inventor
マイケル ジェファーズ,
リチャード エイ. シムケッツ,
サドヒルダス ケイ. プラヤガ,
フェレンク エル. ボルドッグ,
メイジア ヤング,
キャサリン バーゲス,
エルマ フェルナンデス,
ジョン エル. ヘルマン,
ウイリアム ジェイ. ラロケル,
ヘンリ リチェンスタイン,
Original Assignee
キュラジェン コーポレイション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by キュラジェン コーポレイション filed Critical キュラジェン コーポレイション
Publication of JP2003505075A publication Critical patent/JP2003505075A/ja
Publication of JP2003505075A5 publication Critical patent/JP2003505075A5/ja
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factor [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2001512864A 1999-07-27 2000-07-27 新規線維芽細胞増殖因子およびこれをコードする核酸 Pending JP2003505075A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US14589999P 1999-07-27 1999-07-27
US60/145,899 1999-07-27
US49458500A 2000-01-31 2000-01-31
US09/494,585 2000-01-31
US09/609,543 US7056885B1 (en) 1999-07-27 2000-07-03 Fibroblast growth factor and nucleic acids encoding same
US09/609,543 2000-07-03
PCT/US2000/020405 WO2001007595A2 (en) 1999-07-27 2000-07-27 Novel fibroblast growth factor and nucleic acids encoding same

Publications (2)

Publication Number Publication Date
JP2003505075A true JP2003505075A (ja) 2003-02-12
JP2003505075A5 JP2003505075A5 (enExample) 2008-02-21

Family

ID=46203895

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001512864A Pending JP2003505075A (ja) 1999-07-27 2000-07-27 新規線維芽細胞増殖因子およびこれをコードする核酸

Country Status (6)

Country Link
US (1) US7056885B1 (enExample)
EP (1) EP1198563A2 (enExample)
JP (1) JP2003505075A (enExample)
AU (1) AU781980B2 (enExample)
CA (1) CA2380226A1 (enExample)
WO (1) WO2001007595A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007516223A (ja) * 2003-05-09 2007-06-21 キュラジェン コーポレイション 新規線維芽細胞成長因子及びその使用方法
JP2007531702A (ja) * 2003-05-09 2007-11-08 キュラジェン コーポレイション 放射線防護におけるg53135−05(fgf−20)の治療的使用

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7291483B2 (en) 1999-07-27 2007-11-06 Curagen Corporation FGF-CX polynucleotide sequences and methods of producing same
US7056885B1 (en) 1999-07-27 2006-06-06 Curagen Corporation Fibroblast growth factor and nucleic acids encoding same
US7253266B2 (en) 1999-07-27 2007-08-07 Curagen Corporation Polypeptides of FGF-CX
US6797695B1 (en) 1999-10-22 2004-09-28 Kyoto University Human FGF-20 gene and gene expression products
AU1101901A (en) * 1999-10-22 2001-05-08 Chiron Corporation Human fgf-20 gene and gene expression products
US6716626B1 (en) 1999-11-18 2004-04-06 Chiron Corporation Human FGF-21 nucleic acids
US20020037557A1 (en) * 2000-03-13 2002-03-28 Amgen, Inc. Fibroblast growth factor-like molecules and uses thereof
GB2365869A (en) * 2000-05-30 2002-02-27 Smithkline Beecham Corp SbgFGF-9a polynucleotides and polypeptides
WO2001092522A2 (en) * 2000-06-01 2001-12-06 Eli Lilly And Company Human fgf-20 nucleic acids and polypeptides
IL139380A0 (en) 2000-10-31 2001-11-25 Prochon Biotech Ltd Active variants of fibroblast growth factor
US7189693B2 (en) 2000-11-06 2007-03-13 Curagen Corporation Treatment of inflammatory bowel disease using fibroblast growth factor CX polypeptides
US20060094647A1 (en) * 2000-11-06 2006-05-04 Jeffers Michael E Treatment of inflammatory bowel disease using growth factors
US6982250B2 (en) 2000-11-06 2006-01-03 Curagen Corporation Methods of prevention and treatment of inflammatory bowel disease
EP1401855A4 (en) * 2001-06-15 2004-12-22 Curagen Corp NEW FIBROBLAST GROWTH FACTOR AND NUCLEIC ACIDS CODING FOR THIS
IL149562A0 (en) 2002-05-09 2002-11-10 Prochon Ltd Fgf variants and methods for use thereof
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US20050256039A1 (en) * 2003-05-09 2005-11-17 Jeffery Peterson Novel fibroblast growth factors and methods of use thereof
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
WO2005113809A2 (en) * 2004-05-10 2005-12-01 Curagen Corporation Novel fibroblast growth factor and nucleic acids encoding same
JP2007536381A (ja) * 2004-05-10 2007-12-13 キュラジェン コーポレイション 消化管粘膜炎を予防または処置する方法
EP1789072A2 (en) * 2004-05-10 2007-05-30 Curagen Corporation Prophylactic and therapeutic uses of fgf-20 in radiation protection
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
EP1926459B1 (en) 2005-09-19 2015-01-07 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US8685107B2 (en) 2007-07-03 2014-04-01 Histogenics Corporation Double-structured tissue implant and a method for preparation and use thereof
US20090054984A1 (en) 2007-08-20 2009-02-26 Histogenics Corporation Method For Use Of A Double-Structured Tissue Implant For Treatment Of Tissue Defects
WO2009111069A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US8870876B2 (en) 2009-02-13 2014-10-28 Tarsus Medical Inc. Methods and devices for treating hallux valgus
US8277459B2 (en) 2009-09-25 2012-10-02 Tarsus Medical Inc. Methods and devices for treating a structural bone and joint deformity
US8652141B2 (en) 2010-01-21 2014-02-18 Tarsus Medical Inc. Methods and devices for treating hallux valgus
US8696719B2 (en) 2010-06-03 2014-04-15 Tarsus Medical Inc. Methods and devices for treating hallux valgus
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000054813A2 (en) * 1999-03-15 2000-09-21 Chiron Corporation Use of recombinant gene delivery vectors for treating or preventing diseases of the eye

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3385040B2 (ja) * 1991-02-14 2003-03-10 武田薬品工業株式会社 グリア活性化因子およびその製造法
US7056885B1 (en) 1999-07-27 2006-06-06 Curagen Corporation Fibroblast growth factor and nucleic acids encoding same
AU1101901A (en) 1999-10-22 2001-05-08 Chiron Corporation Human fgf-20 gene and gene expression products
US20020037557A1 (en) 2000-03-13 2002-03-28 Amgen, Inc. Fibroblast growth factor-like molecules and uses thereof
AU5056501A (en) 2000-03-31 2001-10-08 Nobuyuki Itoh Fibroblast growth factor-like molecules and uses thereof
WO2001092522A2 (en) 2000-06-01 2001-12-06 Eli Lilly And Company Human fgf-20 nucleic acids and polypeptides
EP1297012A2 (en) 2000-07-03 2003-04-02 Curagen Corporation Novel fibroblast growth factors and nucleic acids encoding same
WO2002024234A2 (en) 2000-09-20 2002-03-28 The Regents Of The University Of California Use of recombinant gene delivery vectors for treating or preventing diseases of the eye

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000054813A2 (en) * 1999-03-15 2000-09-21 Chiron Corporation Use of recombinant gene delivery vectors for treating or preventing diseases of the eye

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6010025382, Advances in Cancer Research, 1992, 59, p.115−165 *
JPN7010001413, Int. J. Cancer, 1989, 43, p.870−874 *
JPN7010001414, Int. J. Oncol., 1994, 4, p.1365−1370 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007516223A (ja) * 2003-05-09 2007-06-21 キュラジェン コーポレイション 新規線維芽細胞成長因子及びその使用方法
JP2007531702A (ja) * 2003-05-09 2007-11-08 キュラジェン コーポレイション 放射線防護におけるg53135−05(fgf−20)の治療的使用

Also Published As

Publication number Publication date
US7056885B1 (en) 2006-06-06
WO2001007595A2 (en) 2001-02-01
WO2001007595A3 (en) 2001-08-16
CA2380226A1 (en) 2001-02-01
AU6495800A (en) 2001-02-13
EP1198563A2 (en) 2002-04-24
AU781980B2 (en) 2005-06-23

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