JP2003504020A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2003504020A5 JP2003504020A5 JP2001508334A JP2001508334A JP2003504020A5 JP 2003504020 A5 JP2003504020 A5 JP 2003504020A5 JP 2001508334 A JP2001508334 A JP 2001508334A JP 2001508334 A JP2001508334 A JP 2001508334A JP 2003504020 A5 JP2003504020 A5 JP 2003504020A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- subunit
- amino acid
- cell
- dna molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 description 8
- 210000004027 cell Anatomy 0.000 description 7
- 108020004414 DNA Proteins 0.000 description 6
- 102000053602 DNA Human genes 0.000 description 6
- 125000003275 alpha amino acid group Chemical group 0.000 description 5
- 108090000312 Calcium Channels Proteins 0.000 description 4
- 102000003922 Calcium Channels Human genes 0.000 description 4
- 150000001413 amino acids Chemical class 0.000 description 4
- 239000002299 complementary DNA Substances 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005215 recombination Methods 0.000 description 2
- 108091026890 Coding region Proteins 0.000 description 1
- 102000003691 T-Type Calcium Channels Human genes 0.000 description 1
- 108090000030 T-Type Calcium Channels Proteins 0.000 description 1
- 125000000539 amino acid group Chemical group 0.000 description 1
- 230000000692 anti-sense effect Effects 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000001086 cytosolic effect Effects 0.000 description 1
- 230000002964 excitative effect Effects 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 210000004962 mammalian cell Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- 239000013600 plasmid vector Substances 0.000 description 1
- 210000001103 thalamus Anatomy 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/346,794 | 1999-07-02 | ||
| US09/346,794 US7297504B1 (en) | 1997-02-28 | 1999-07-02 | Methods for identifying agonists and antagonists of human T-type calcium channels |
| PCT/CA2000/000794 WO2001002561A2 (en) | 1999-07-02 | 2000-07-04 | Mammalian calcium channels and related probes, cell lines and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003504020A JP2003504020A (ja) | 2003-02-04 |
| JP2003504020A5 true JP2003504020A5 (enExample) | 2007-08-23 |
Family
ID=23361077
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001508334A Pending JP2003504020A (ja) | 1999-07-02 | 2000-07-04 | 新規な哺乳動物カルシウムチャネルならびに関連するプローブ、細胞株および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US7157243B1 (enExample) |
| EP (2) | EP1190053A2 (enExample) |
| JP (1) | JP2003504020A (enExample) |
| AU (1) | AU5957100A (enExample) |
| CA (1) | CA2377931A1 (enExample) |
| WO (1) | WO2001002561A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020009772A1 (en) * | 1997-02-28 | 2002-01-24 | Terry P. Snutch | Novel human calcium channels and related probes, cell lines and mehtods |
| US6358706B1 (en) * | 1999-10-26 | 2002-03-19 | Ortho-Mcneil Pharmaceutical, Inc. | DNA encoding human alpha1G-C T-Type calcium channel |
| EP1465609A2 (en) * | 2001-11-07 | 2004-10-13 | Medical Research Council | Modulation of dopaminergic neurons |
| WO2004035000A2 (en) * | 2002-10-17 | 2004-04-29 | Merck & Co., Inc. | Enhancement of sleep with t-type calcium channel antagonists |
| WO2004060917A2 (en) | 2003-01-07 | 2004-07-22 | Neuromed Technologies, Inc. | Fluorescence based t-type channel assay |
| US7157461B2 (en) | 2003-07-23 | 2007-01-02 | Bristol-Myers Squibb Co. | Substituted dihydropyrimidine inhibitors of calcium channel function |
| US7166603B2 (en) | 2003-07-23 | 2007-01-23 | Bristol-Myers Squibb Co. | Dihydropyrimidone inhibitors of calcium channel function |
| US7195893B2 (en) | 2003-08-14 | 2007-03-27 | Neuromed Pharmaceuticals Ltd. | Nucleic acids encoding α2δ calcium channel subunits and methods for making and using them |
| US7504431B2 (en) | 2004-04-16 | 2009-03-17 | Bristol-Myers Squibb Company | Sulfonyl amide inhibitors of calcium channel function |
| ES2842289T3 (es) | 2008-02-29 | 2021-07-13 | Vm Therapeutics Llc | Compuestos para tratar el síndrome del dolor y otros trastornos |
| US12365898B2 (en) | 2021-06-29 | 2025-07-22 | The Medical College Of Wisconsin, Inc. | Calcium channel 3.2 inhibitory peptides and uses thereof |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5386025A (en) * | 1990-02-20 | 1995-01-31 | The Salk Institute Biotechnology/Industrial Associates | Calcium channel compositions and methods |
| US5429921A (en) * | 1988-04-04 | 1995-07-04 | The Salk Institute Biotechnology/Industrial Assoc. Inc. | Assays for agonists and antagonists of recombinant human calcium channels |
| US5401629A (en) * | 1990-08-07 | 1995-03-28 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Assay methods and compositions useful for measuring the transduction of an intracellular signal |
| DE4110785A1 (de) | 1991-04-04 | 1992-10-08 | Bayer Ag | Gewebe-spezifische humane neuronale calcium-kanal-subtypen und deren verwendung |
| US5688938A (en) * | 1991-08-23 | 1997-11-18 | The Brigham & Women's Hospital, Inc. | Calcium receptor-active molecules |
| US5837479A (en) * | 1992-09-22 | 1998-11-17 | Young; Donald A. | Screening assays for inhibitors of mammalian prostaglandin H synthase-2 |
| EP0778890B1 (en) | 1993-07-30 | 2000-09-27 | Elan Pharmaceuticals, Inc. | Dna encoding a human calcium channel alpha-1e subunit |
| US5712158A (en) | 1995-06-06 | 1998-01-27 | Warner-Lambert Company | Cell line for the rapid expression of functional calcium channels |
| US5804436A (en) * | 1996-08-02 | 1998-09-08 | Axiom Biotechnologies, Inc. | Apparatus and method for real-time measurement of cellular response |
| US7297504B1 (en) * | 1997-02-28 | 2007-11-20 | Neuromed Pharmaceuticals Ltd. | Methods for identifying agonists and antagonists of human T-type calcium channels |
| US20020009772A1 (en) * | 1997-02-28 | 2002-01-24 | Terry P. Snutch | Novel human calcium channels and related probes, cell lines and mehtods |
| US6528630B1 (en) | 1997-12-03 | 2003-03-04 | Merck & Co., Inc. | Calcium channel compositions and methods |
| EP1042468B1 (en) * | 1997-12-03 | 2006-10-18 | Merck & Co., Inc. | Low-voltage activated calcium channel compositions and methods |
| EP1036170A1 (en) * | 1997-12-05 | 2000-09-20 | Loyola University Of Chicago | T-type voltage-gated calcium channels and method of using same |
| US20030125269A1 (en) | 1998-08-26 | 2003-07-03 | Ming Li | T-type calcium channel |
| US6309858B1 (en) | 1998-09-29 | 2001-10-30 | Syntex (U.S.A.) Llc | T-type calcium channel variants; compositions thereof; and uses |
| WO2000070044A2 (en) | 1999-05-13 | 2000-11-23 | The Johns Hopkins University | Human brain t calcium channel alpha-subunit splice variants |
| US6783933B1 (en) | 1999-09-15 | 2004-08-31 | The Johns Hopkins University School Of Medicine | CACNA1G polynucleotide, polypeptide and methods of use therefor |
| US6358706B1 (en) * | 1999-10-26 | 2002-03-19 | Ortho-Mcneil Pharmaceutical, Inc. | DNA encoding human alpha1G-C T-Type calcium channel |
-
2000
- 2000-07-04 EP EP00945479A patent/EP1190053A2/en not_active Withdrawn
- 2000-07-04 JP JP2001508334A patent/JP2003504020A/ja active Pending
- 2000-07-04 CA CA002377931A patent/CA2377931A1/en not_active Abandoned
- 2000-07-04 EP EP06115615A patent/EP1780278A3/en not_active Withdrawn
- 2000-07-04 WO PCT/CA2000/000794 patent/WO2001002561A2/en not_active Ceased
- 2000-07-04 AU AU59571/00A patent/AU5957100A/en not_active Abandoned
- 2000-07-06 US US09/611,257 patent/US7157243B1/en not_active Expired - Fee Related
-
2007
- 2007-01-03 US US11/649,451 patent/US7501263B2/en not_active Expired - Fee Related
- 2007-01-03 US US11/649,452 patent/US7517672B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Dulhanty et al. | Phosphorylation by cAMP-dependent protein kinase causes a conformational change in the R domain of the cystic fibrosis transmembrane conductance regulator | |
| KR102366078B1 (ko) | Pkk 발현을 조절하는 조성물 및 방법 | |
| JP2003504020A5 (enExample) | ||
| CA2738209C (en) | Recombinant proteins having haemostatic activity and capable of inducing platelet aggregation | |
| AU2024205598A1 (en) | Chimeric antigen receptors and uses thereof. | |
| MacNeil et al. | Cloning and pharmacological characterization of a rabbit bradykinin B1 receptor | |
| Mital et al. | RNA polymerase III transcription from the human U6 and adenovirus type 2 VAI promoters has different requirements for human BRF, a subunit of human TFIIIB | |
| ES2625316T3 (es) | Neuquinasa, una proteína corriente abajo de neuregulina | |
| JP2004267216A5 (enExample) | ||
| CA2443617A1 (en) | Repeat sequences of the ca125 gene and their use for diagnostic and therapeutic interventions | |
| Kludkiewicz et al. | Structure and expression of the silk adhesive protein Ser2 in Bombyx mori | |
| Wehrli et al. | Cloning and characterization of αPS1, a novel Drosophila melanogaster integrin | |
| CN114929735A (zh) | 因子viii构建体 | |
| JP2004536585A5 (enExample) | ||
| IE66333B1 (en) | Compositions and methods for the syntheses and assay of enkephalinase | |
| Luneau et al. | Shaw‐like rat brain potassium channel cDNA's with divergent 3′ ends | |
| JP2013526840A5 (enExample) | ||
| WO2002050258A1 (en) | Novel aggrecanase | |
| JP2013502217A5 (enExample) | ||
| JP2003530821A5 (enExample) | ||
| JP2003524389A5 (enExample) | ||
| Paesen et al. | A tick homologue of the human Ki nuclear autoantigen | |
| Ishikawa et al. | Cloning of the mouse desmoglein 3 gene (Dsg3): interspecies conservation within the cadherin superfamily | |
| JPWO2021226348A5 (enExample) | ||
| WO2003070768A3 (en) | Cd40 splice variants,method of detection thereof, compositions comprising said variant(s) or nucleic acid encoding the same and use thereof |