JP2003504020A - 新規な哺乳動物カルシウムチャネルならびに関連するプローブ、細胞株および方法 - Google Patents
新規な哺乳動物カルシウムチャネルならびに関連するプローブ、細胞株および方法Info
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- JP2003504020A JP2003504020A JP2001508334A JP2001508334A JP2003504020A JP 2003504020 A JP2003504020 A JP 2003504020A JP 2001508334 A JP2001508334 A JP 2001508334A JP 2001508334 A JP2001508334 A JP 2001508334A JP 2003504020 A JP2003504020 A JP 2003504020A
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- calcium channel
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- calcium
- channels
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/346,794 | 1999-07-02 | ||
| US09/346,794 US7297504B1 (en) | 1997-02-28 | 1999-07-02 | Methods for identifying agonists and antagonists of human T-type calcium channels |
| PCT/CA2000/000794 WO2001002561A2 (en) | 1999-07-02 | 2000-07-04 | Mammalian calcium channels and related probes, cell lines and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003504020A true JP2003504020A (ja) | 2003-02-04 |
| JP2003504020A5 JP2003504020A5 (enExample) | 2007-08-23 |
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Family Applications (1)
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| JP2001508334A Pending JP2003504020A (ja) | 1999-07-02 | 2000-07-04 | 新規な哺乳動物カルシウムチャネルならびに関連するプローブ、細胞株および方法 |
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| US (3) | US7157243B1 (enExample) |
| EP (2) | EP1190053A2 (enExample) |
| JP (1) | JP2003504020A (enExample) |
| AU (1) | AU5957100A (enExample) |
| CA (1) | CA2377931A1 (enExample) |
| WO (1) | WO2001002561A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020009772A1 (en) * | 1997-02-28 | 2002-01-24 | Terry P. Snutch | Novel human calcium channels and related probes, cell lines and mehtods |
| US6358706B1 (en) * | 1999-10-26 | 2002-03-19 | Ortho-Mcneil Pharmaceutical, Inc. | DNA encoding human alpha1G-C T-Type calcium channel |
| EP1465609A2 (en) * | 2001-11-07 | 2004-10-13 | Medical Research Council | Modulation of dopaminergic neurons |
| WO2004035000A2 (en) * | 2002-10-17 | 2004-04-29 | Merck & Co., Inc. | Enhancement of sleep with t-type calcium channel antagonists |
| WO2004060917A2 (en) | 2003-01-07 | 2004-07-22 | Neuromed Technologies, Inc. | Fluorescence based t-type channel assay |
| US7157461B2 (en) | 2003-07-23 | 2007-01-02 | Bristol-Myers Squibb Co. | Substituted dihydropyrimidine inhibitors of calcium channel function |
| US7166603B2 (en) | 2003-07-23 | 2007-01-23 | Bristol-Myers Squibb Co. | Dihydropyrimidone inhibitors of calcium channel function |
| US7195893B2 (en) | 2003-08-14 | 2007-03-27 | Neuromed Pharmaceuticals Ltd. | Nucleic acids encoding α2δ calcium channel subunits and methods for making and using them |
| US7504431B2 (en) | 2004-04-16 | 2009-03-17 | Bristol-Myers Squibb Company | Sulfonyl amide inhibitors of calcium channel function |
| ES2842289T3 (es) | 2008-02-29 | 2021-07-13 | Vm Therapeutics Llc | Compuestos para tratar el síndrome del dolor y otros trastornos |
| US12365898B2 (en) | 2021-06-29 | 2025-07-22 | The Medical College Of Wisconsin, Inc. | Calcium channel 3.2 inhibitory peptides and uses thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998038301A1 (en) * | 1997-02-28 | 1998-09-03 | Neuromed Technologies Inc. | Human calcium channels alfa1 subunits and related probes, cell lines and methods |
| WO1999028342A2 (en) * | 1997-12-03 | 1999-06-10 | Merck & Co., Inc. | Low-voltage activated calcium channel compositions and methods |
| WO1999029847A1 (en) * | 1997-12-05 | 1999-06-17 | Loyola University Of Chicago | T-type voltage-gated calcium channels and method of using same |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5386025A (en) * | 1990-02-20 | 1995-01-31 | The Salk Institute Biotechnology/Industrial Associates | Calcium channel compositions and methods |
| US5429921A (en) * | 1988-04-04 | 1995-07-04 | The Salk Institute Biotechnology/Industrial Assoc. Inc. | Assays for agonists and antagonists of recombinant human calcium channels |
| US5401629A (en) * | 1990-08-07 | 1995-03-28 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Assay methods and compositions useful for measuring the transduction of an intracellular signal |
| DE4110785A1 (de) | 1991-04-04 | 1992-10-08 | Bayer Ag | Gewebe-spezifische humane neuronale calcium-kanal-subtypen und deren verwendung |
| US5688938A (en) * | 1991-08-23 | 1997-11-18 | The Brigham & Women's Hospital, Inc. | Calcium receptor-active molecules |
| US5837479A (en) * | 1992-09-22 | 1998-11-17 | Young; Donald A. | Screening assays for inhibitors of mammalian prostaglandin H synthase-2 |
| EP0778890B1 (en) | 1993-07-30 | 2000-09-27 | Elan Pharmaceuticals, Inc. | Dna encoding a human calcium channel alpha-1e subunit |
| US5712158A (en) | 1995-06-06 | 1998-01-27 | Warner-Lambert Company | Cell line for the rapid expression of functional calcium channels |
| US5804436A (en) * | 1996-08-02 | 1998-09-08 | Axiom Biotechnologies, Inc. | Apparatus and method for real-time measurement of cellular response |
| US7297504B1 (en) * | 1997-02-28 | 2007-11-20 | Neuromed Pharmaceuticals Ltd. | Methods for identifying agonists and antagonists of human T-type calcium channels |
| US6528630B1 (en) | 1997-12-03 | 2003-03-04 | Merck & Co., Inc. | Calcium channel compositions and methods |
| US20030125269A1 (en) | 1998-08-26 | 2003-07-03 | Ming Li | T-type calcium channel |
| US6309858B1 (en) | 1998-09-29 | 2001-10-30 | Syntex (U.S.A.) Llc | T-type calcium channel variants; compositions thereof; and uses |
| WO2000070044A2 (en) | 1999-05-13 | 2000-11-23 | The Johns Hopkins University | Human brain t calcium channel alpha-subunit splice variants |
| US6783933B1 (en) | 1999-09-15 | 2004-08-31 | The Johns Hopkins University School Of Medicine | CACNA1G polynucleotide, polypeptide and methods of use therefor |
| US6358706B1 (en) * | 1999-10-26 | 2002-03-19 | Ortho-Mcneil Pharmaceutical, Inc. | DNA encoding human alpha1G-C T-Type calcium channel |
-
2000
- 2000-07-04 EP EP00945479A patent/EP1190053A2/en not_active Withdrawn
- 2000-07-04 JP JP2001508334A patent/JP2003504020A/ja active Pending
- 2000-07-04 CA CA002377931A patent/CA2377931A1/en not_active Abandoned
- 2000-07-04 EP EP06115615A patent/EP1780278A3/en not_active Withdrawn
- 2000-07-04 WO PCT/CA2000/000794 patent/WO2001002561A2/en not_active Ceased
- 2000-07-04 AU AU59571/00A patent/AU5957100A/en not_active Abandoned
- 2000-07-06 US US09/611,257 patent/US7157243B1/en not_active Expired - Fee Related
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2007
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- 2007-01-03 US US11/649,452 patent/US7517672B2/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998038301A1 (en) * | 1997-02-28 | 1998-09-03 | Neuromed Technologies Inc. | Human calcium channels alfa1 subunits and related probes, cell lines and methods |
| WO1999028342A2 (en) * | 1997-12-03 | 1999-06-10 | Merck & Co., Inc. | Low-voltage activated calcium channel compositions and methods |
| WO1999029847A1 (en) * | 1997-12-05 | 1999-06-17 | Loyola University Of Chicago | T-type voltage-gated calcium channels and method of using same |
Also Published As
| Publication number | Publication date |
|---|---|
| US20070207523A1 (en) | 2007-09-06 |
| EP1780278A3 (en) | 2007-06-27 |
| WO2001002561A3 (en) | 2001-06-28 |
| AU5957100A (en) | 2001-01-22 |
| WO2001002561A2 (en) | 2001-01-11 |
| US7157243B1 (en) | 2007-01-02 |
| CA2377931A1 (en) | 2001-01-11 |
| EP1190053A2 (en) | 2002-03-27 |
| US7517672B2 (en) | 2009-04-14 |
| US7501263B2 (en) | 2009-03-10 |
| US20070178553A1 (en) | 2007-08-02 |
| EP1780278A2 (en) | 2007-05-02 |
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