JP2003500457A - 非ランゲルハンス島組織における調節された膵臓ホルモンを誘導する方法 - Google Patents

非ランゲルハンス島組織における調節された膵臓ホルモンを誘導する方法

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Publication number
JP2003500457A
JP2003500457A JP2000620991A JP2000620991A JP2003500457A JP 2003500457 A JP2003500457 A JP 2003500457A JP 2000620991 A JP2000620991 A JP 2000620991A JP 2000620991 A JP2000620991 A JP 2000620991A JP 2003500457 A JP2003500457 A JP 2003500457A
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JP
Japan
Prior art keywords
pdx
nucleic acid
subject
acid encoding
expression
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Pending
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JP2000620991A
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English (en)
Japanese (ja)
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JP2003500457A5 (https=
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サラ ファーバー，
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Individual
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Publication of JP2003500457A publication Critical patent/JP2003500457A/ja
Publication of JP2003500457A5 publication Critical patent/JP2003500457A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2000620991A 1999-06-01 2000-06-01 非ランゲルハンス島組織における調節された膵臓ホルモンを誘導する方法 Pending JP2003500457A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US13714399P 1999-06-01 1999-06-01
US60/137,143 1999-06-01
US19853200P 2000-04-19 2000-04-19
US60/198,532 2000-04-19
US09/584,216 US6774120B1 (en) 1999-06-01 2000-05-31 Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues
US09/584,216 2000-05-31
PCT/IB2000/000824 WO2000072885A2 (en) 1999-06-01 2000-06-01 Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010288937A Division JP2011057716A (ja) 1999-06-01 2010-12-24 非ランゲルハンス島組織における調節された膵臓ホルモンを誘導する方法

Publications (2)

Publication Number Publication Date
JP2003500457A true JP2003500457A (ja) 2003-01-07
JP2003500457A5 JP2003500457A5 (https=) 2011-02-17

Family

ID=27384964

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000620991A Pending JP2003500457A (ja) 1999-06-01 2000-06-01 非ランゲルハンス島組織における調節された膵臓ホルモンを誘導する方法
JP2010288937A Pending JP2011057716A (ja) 1999-06-01 2010-12-24 非ランゲルハンス島組織における調節された膵臓ホルモンを誘導する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010288937A Pending JP2011057716A (ja) 1999-06-01 2010-12-24 非ランゲルハンス島組織における調節された膵臓ホルモンを誘導する方法

Country Status (8)

Country Link
US (3) US6774120B1 (https=)
EP (1) EP1180143B1 (https=)
JP (2) JP2003500457A (https=)
AT (1) ATE361977T1 (https=)
AU (1) AU779619B2 (https=)
CA (1) CA2371995C (https=)
DE (1) DE60034781T2 (https=)
WO (1) WO2000072885A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006525994A (ja) * 2003-05-12 2006-11-16 サラ ファーバー， 非膵島組織における調節された膵ホルモンの産生を誘導する方法

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US6774120B1 (en) 1999-06-01 2004-08-10 Sarah Ferber Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues
US8778899B2 (en) 1999-06-01 2014-07-15 Sarah Ferber Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues
US7567870B1 (en) * 2000-07-31 2009-07-28 Institute For Systems Biology Multiparameter analysis for predictive medicine
CA2442177A1 (en) 2001-03-29 2002-10-10 Ixion Biotechnology, Inc. Method for transdifferentiation of non-pancreatic stem cells to the pancreatic differentiation pathway
US7343247B2 (en) * 2001-07-30 2008-03-11 The Institute For Systems Biology Methods of classifying drug responsiveness using multiparameter analysis
CA2463914A1 (en) * 2001-10-18 2003-04-24 Ixion Biotechnology, Inc. Conversion of liver stem and progenitor cells to pancreatic functional cells
CN1599793A (zh) 2001-12-07 2005-03-23 杰龙公司 人胚胎干细胞衍生的软骨细胞前体
IL162131A0 (en) 2001-12-07 2005-11-20 Geron Corp Islet cells from human embryonic stem cells
JP2003189875A (ja) * 2001-12-28 2003-07-08 Japan Science & Technology Corp 膵β細胞関連転写因子の遺伝子導入によるインスリン産生細胞の形成誘導
GB0206357D0 (en) * 2002-03-18 2002-05-01 Univ Bath Cells
JP4136434B2 (ja) * 2002-04-17 2008-08-20 進 清野 インスリン産生細胞の誘導
GB0300208D0 (en) * 2003-01-06 2003-02-05 Oxford Biomedica Ltd Insulin producing cells
EP1617888B1 (en) 2003-04-23 2019-06-12 Valeritas, Inc. Hydraulically actuated pump for long duration medicament administration
WO2005083059A1 (en) * 2004-02-23 2005-09-09 University Of Florida Compositions and methods for making insulin-producing cells
WO2006014425A1 (en) 2004-07-02 2006-02-09 Biovalve Technologies, Inc. Methods and devices for delivering glp-1 and uses thereof
WO2006010531A1 (en) * 2004-07-28 2006-02-02 F. Hoffmann-La Roche Ag Prohormone convertase i as target/marker for beta cell failure
CA2593549C (en) * 2005-01-07 2016-04-26 Wake Forest University Health Sciences Regeneration of pancreatic islets by amniotic fluid stem cell therapy
JP2007061096A (ja) * 2005-08-31 2007-03-15 Lifescan Inc 細胞分化を促進する方法
JP2007063225A (ja) 2005-09-01 2007-03-15 Takeda Chem Ind Ltd イミダゾピリジン化合物
US8673635B2 (en) 2005-12-21 2014-03-18 Universite Catholique De Louvain Isolated liver stem cells
EP2001875A2 (en) 2006-03-08 2008-12-17 Takeda San Diego, Inc. Glucokinase activators
KR101361376B1 (ko) 2006-03-30 2014-02-10 발레리타스 인코포레이티드 복합-카트리지 유체 전달 장치
EP2049518B1 (en) 2006-05-31 2011-08-31 Takeda San Diego, Inc. Indazole and isoindole derivatives as glucokinase activating agents.
US8415153B2 (en) 2006-06-19 2013-04-09 Geron Corporation Differentiation and enrichment of islet-like cells from human pluripotent stem cells
US8163779B2 (en) 2006-12-20 2012-04-24 Takeda San Diego, Inc. Glucokinase activators
US8173645B2 (en) 2007-03-21 2012-05-08 Takeda San Diego, Inc. Glucokinase activators
CN102154210A (zh) * 2010-12-28 2011-08-17 沈达青 一种胰岛素基因修饰的肝干细胞制法及其应用和制剂
JP6650393B2 (ja) 2013-06-13 2020-02-19 オージェネシス リミテッド 細胞の集団、分化転換の方法及びその使用方法
ES2759228T3 (es) 2013-07-05 2020-05-08 Univ Catholique Louvain Medio acondicionado de células madre de hígado de adultos y su uso en el tratamiento de trastornos del hígado
MA41296A (fr) 2014-12-30 2017-11-07 Orgenesis Ltd Procédés de transdifférenciation et procédés d'utilisation de ceux-ci
EP3635106A4 (en) 2017-05-08 2021-01-06 Orgenesis Ltd. POPULATIONS OF TRANSDIFFERENTIATED CELLS AND THEIR METHODS OF USE

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WO1997049728A1 (en) * 1996-06-24 1997-12-31 Vivorx Pharmaceuticals, Inc. Methods for the isolation and proliferation of insulin-secreting cells
JP2000501290A (ja) * 1995-11-30 2000-02-08 リサーチ ディベロップメント ファンデーション ソマトスタチン及びインシュリン生成を刺激する化合物のスクリーニング・アッセイ

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CA2463914A1 (en) 2001-10-18 2003-04-24 Ixion Biotechnology, Inc. Conversion of liver stem and progenitor cells to pancreatic functional cells
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JP2000501290A (ja) * 1995-11-30 2000-02-08 リサーチ ディベロップメント ファンデーション ソマトスタチン及びインシュリン生成を刺激する化合物のスクリーニング・アッセイ
WO1997049728A1 (en) * 1996-06-24 1997-12-31 Vivorx Pharmaceuticals, Inc. Methods for the isolation and proliferation of insulin-secreting cells

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006525994A (ja) * 2003-05-12 2006-11-16 サラ ファーバー， 非膵島組織における調節された膵ホルモンの産生を誘導する方法
JP2011068660A (ja) * 2003-05-12 2011-04-07 Sarah Ferber 非膵島組織における調節された膵ホルモンの産生を誘導する方法

Also Published As

Publication number Publication date
US8119405B2 (en) 2012-02-21
US20040213769A1 (en) 2004-10-28
WO2000072885A2 (en) 2000-12-07
ATE361977T1 (de) 2007-06-15
US20120329710A1 (en) 2012-12-27
EP1180143B1 (en) 2007-05-09
EP1180143A2 (en) 2002-02-20
WO2000072885A9 (en) 2001-03-01
AU779619B2 (en) 2005-02-03
AU5097400A (en) 2000-12-18
DE60034781D1 (de) 2007-06-21
JP2011057716A (ja) 2011-03-24
CA2371995C (en) 2014-01-21
WO2000072885A3 (en) 2001-05-10
DE60034781T2 (de) 2008-01-17
US6774120B1 (en) 2004-08-10
CA2371995A1 (en) 2000-12-07

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