JP2003500059A5 - - Google Patents
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- Publication number
- JP2003500059A5 JP2003500059A5 JP2000620108A JP2000620108A JP2003500059A5 JP 2003500059 A5 JP2003500059 A5 JP 2003500059A5 JP 2000620108 A JP2000620108 A JP 2000620108A JP 2000620108 A JP2000620108 A JP 2000620108A JP 2003500059 A5 JP2003500059 A5 JP 2003500059A5
- Authority
- JP
- Japan
- Prior art keywords
- host cell
- bacteriophage
- temperature
- protein
- coli
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000623 proteins and genes Proteins 0.000 description 17
- 241000588724 Escherichia coli Species 0.000 description 12
- 241000701959 Escherichia virus Lambda Species 0.000 description 12
- 238000000034 method Methods 0.000 description 12
- 102000004169 proteins and genes Human genes 0.000 description 9
- 230000035772 mutation Effects 0.000 description 8
- 230000009089 cytolysis Effects 0.000 description 7
- 208000015181 infectious disease Diseases 0.000 description 4
- 230000000975 bioactive effect Effects 0.000 description 3
- 230000002950 deficient Effects 0.000 description 3
- 238000012258 culturing Methods 0.000 description 2
- 230000002458 infectious effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000013612 plasmid Substances 0.000 description 2
- 102000014150 Interferons Human genes 0.000 description 1
- 108010050904 Interferons Proteins 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 229940079322 interferon Drugs 0.000 description 1
- 230000002934 lysing effect Effects 0.000 description 1
- 230000002101 lytic effect Effects 0.000 description 1
- 101150079601 recA gene Proteins 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/318,288 US6268178B1 (en) | 1999-05-25 | 1999-05-25 | Phage-dependent super-production of biologically active protein and peptides |
| US09/318,288 | 1999-05-25 | ||
| PCT/US2000/040020 WO2000071731A1 (en) | 1999-05-25 | 2000-05-24 | Phage-dependent super-production of biologically active protein and peptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003500059A JP2003500059A (ja) | 2003-01-07 |
| JP2003500059A5 true JP2003500059A5 (enExample) | 2007-07-19 |
Family
ID=23237514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000620108A Pending JP2003500059A (ja) | 1999-05-25 | 2000-05-24 | 生物活性タンパク質およびペプチドのファージ依存大量生成 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6268178B1 (enExample) |
| EP (1) | EP1180153B1 (enExample) |
| JP (1) | JP2003500059A (enExample) |
| AT (1) | ATE293170T1 (enExample) |
| AU (1) | AU5049100A (enExample) |
| DE (1) | DE60019411T2 (enExample) |
| WO (1) | WO2000071731A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7252818B2 (en) * | 1998-07-24 | 2007-08-07 | Cardiovascular Biotherapeutics, Inc. | Method of producing biologically active human acidic fibroblast growth factor and its use in promoting angiogenesis |
| US6268178B1 (en) * | 1999-05-25 | 2001-07-31 | Phage Biotechnology Corp. | Phage-dependent super-production of biologically active protein and peptides |
| KR100861240B1 (ko) | 2000-08-15 | 2008-10-02 | 카디오배스큘러 바이오 떼러퓨틱스, 인크. | 생물학적으로 활성인 인간 산성 섬유아세포 성장인자의제조방법과 맥관형성 촉진을 위한 그 용도 |
| US6773899B2 (en) * | 2000-08-15 | 2004-08-10 | Phage Biotechnology Corporation | Phage-dependent superproduction of biologically active protein and peptides |
| WO2004027064A2 (en) * | 2002-09-18 | 2004-04-01 | Centre Hospitalier De L'universite De Montreal (Chum) | Ghrh analogues |
| WO2019068006A1 (en) * | 2017-09-29 | 2019-04-04 | The Charles Stark Draper Laboratory, Inc. | CELLULAR LYSE CONTROLLED BY STIMULUS |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE276694C (enExample) | ||||
| IN151589B (enExample) | 1978-12-22 | 1983-05-28 | Biogen Nv | |
| CH657141A5 (de) | 1980-07-01 | 1986-08-15 | Hoffmann La Roche | Dns-sequenzen, rekombinante expressionsvektoren zur mikrobiellen herstellung von human-leukozyten-interferonen und transformierte mikroorganismen. |
| US4775622A (en) | 1982-03-08 | 1988-10-04 | Genentech, Inc. | Expression, processing and secretion of heterologous protein by yeast |
| CA1209501A (en) | 1982-09-16 | 1986-08-12 | Nikos Panayotatos | Expression vector |
| JPS5979746A (ja) | 1982-10-30 | 1984-05-09 | Mitsubishi Heavy Ind Ltd | 加硫機用制御装置 |
| SU1089119A1 (ru) * | 1982-11-29 | 1984-04-30 | Институт Молекулярной Биологии И Генетики Ан Усср | Способ получени @ -лактамазы |
| GB2143238A (en) | 1983-03-31 | 1985-02-06 | Dr Anthony Stuart Breeze | A method for enzyme liberation from bacterial cells |
| US4637980A (en) * | 1983-08-09 | 1987-01-20 | Smithkline Beckman Corporation | Externalization of products of bacteria |
| CA1309044C (en) | 1987-11-09 | 1992-10-20 | Toshiya Takano | Method of producing foreign gene products |
| IL92124A (en) | 1988-10-28 | 1996-10-31 | Sidney Pestka | Recombinant proteins modified to contain post-phosphorylation that do not occur in nature |
| US5102797A (en) | 1989-05-26 | 1992-04-07 | Dna Plant Technology Corporation | Introduction of heterologous genes into bacteria using transposon flanked expression cassette and a binary vector system |
| US5196318A (en) | 1990-06-26 | 1993-03-23 | The Texas A&M University System | Precisely regulated expression of deleterious genes |
| NZ314630A (en) | 1991-01-17 | 2000-11-24 | Harvard College | Use of trans-splicing ribozymes for genetic modification and cell ablation in a host cell |
| US5346830A (en) | 1991-06-11 | 1994-09-13 | The Center For Innovative Technology | Gene expression system based on regulatory elements of bateriophage P2 and satellite phage P4 |
| US5834233A (en) | 1992-04-06 | 1998-11-10 | Gx Biosystems A/S | Method of limiting the survival of genetically engineered microorganisms in their enivronment |
| US5622852A (en) | 1994-10-31 | 1997-04-22 | Washington University | Bcl-x/Bcl-2 associated cell death regulator |
| US5861273A (en) | 1993-12-21 | 1999-01-19 | Celtrix Phamraceuticals, Inc. | Chromosomal expression of heterologous genes in bacterial cells |
| US6268178B1 (en) * | 1999-05-25 | 2001-07-31 | Phage Biotechnology Corp. | Phage-dependent super-production of biologically active protein and peptides |
| KR100861240B1 (ko) * | 2000-08-15 | 2008-10-02 | 카디오배스큘러 바이오 떼러퓨틱스, 인크. | 생물학적으로 활성인 인간 산성 섬유아세포 성장인자의제조방법과 맥관형성 촉진을 위한 그 용도 |
| US6773899B2 (en) * | 2000-08-15 | 2004-08-10 | Phage Biotechnology Corporation | Phage-dependent superproduction of biologically active protein and peptides |
-
1999
- 1999-05-25 US US09/318,288 patent/US6268178B1/en not_active Expired - Fee Related
-
2000
- 2000-05-24 AU AU50491/00A patent/AU5049100A/en not_active Abandoned
- 2000-05-24 JP JP2000620108A patent/JP2003500059A/ja active Pending
- 2000-05-24 EP EP00932819A patent/EP1180153B1/en not_active Expired - Lifetime
- 2000-05-24 DE DE60019411T patent/DE60019411T2/de not_active Expired - Lifetime
- 2000-05-24 WO PCT/US2000/040020 patent/WO2000071731A1/en not_active Ceased
- 2000-05-24 AT AT00932819T patent/ATE293170T1/de active
-
2001
- 2001-05-17 US US09/859,651 patent/US6794162B2/en not_active Expired - Fee Related
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