ATE293170T1 - Phage-abhängige superproduktion von biologisch aktiven proteinen und peptiden - Google Patents

Phage-abhängige superproduktion von biologisch aktiven proteinen und peptiden

Info

Publication number
ATE293170T1
ATE293170T1 AT00932819T AT00932819T ATE293170T1 AT E293170 T1 ATE293170 T1 AT E293170T1 AT 00932819 T AT00932819 T AT 00932819T AT 00932819 T AT00932819 T AT 00932819T AT E293170 T1 ATE293170 T1 AT E293170T1
Authority
AT
Austria
Prior art keywords
phage
peptides
biologically active
active proteins
cells
Prior art date
Application number
AT00932819T
Other languages
German (de)
English (en)
Inventor
Vitaliy A Kordyum
Svetlana I Chernykh
Irina Y Slavchenko
Oleksandr F Vozianov
Original Assignee
Phage Biotechnology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phage Biotechnology Corp filed Critical Phage Biotechnology Corp
Application granted granted Critical
Publication of ATE293170T1 publication Critical patent/ATE293170T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/73—Expression systems using phage (lambda) regulatory sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10111—Myoviridae
    • C12N2795/10141—Use of virus, viral particle or viral elements as a vector
    • C12N2795/10143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT00932819T 1999-05-25 2000-05-24 Phage-abhängige superproduktion von biologisch aktiven proteinen und peptiden ATE293170T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/318,288 US6268178B1 (en) 1999-05-25 1999-05-25 Phage-dependent super-production of biologically active protein and peptides
PCT/US2000/040020 WO2000071731A1 (en) 1999-05-25 2000-05-24 Phage-dependent super-production of biologically active protein and peptides

Publications (1)

Publication Number Publication Date
ATE293170T1 true ATE293170T1 (de) 2005-04-15

Family

ID=23237514

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00932819T ATE293170T1 (de) 1999-05-25 2000-05-24 Phage-abhängige superproduktion von biologisch aktiven proteinen und peptiden

Country Status (7)

Country Link
US (2) US6268178B1 (enExample)
EP (1) EP1180153B1 (enExample)
JP (1) JP2003500059A (enExample)
AT (1) ATE293170T1 (enExample)
AU (1) AU5049100A (enExample)
DE (1) DE60019411T2 (enExample)
WO (1) WO2000071731A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7252818B2 (en) * 1998-07-24 2007-08-07 Cardiovascular Biotherapeutics, Inc. Method of producing biologically active human acidic fibroblast growth factor and its use in promoting angiogenesis
US6268178B1 (en) * 1999-05-25 2001-07-31 Phage Biotechnology Corp. Phage-dependent super-production of biologically active protein and peptides
KR100861240B1 (ko) 2000-08-15 2008-10-02 카디오배스큘러 바이오 떼러퓨틱스, 인크. 생물학적으로 활성인 인간 산성 섬유아세포 성장인자의제조방법과 맥관형성 촉진을 위한 그 용도
US6773899B2 (en) * 2000-08-15 2004-08-10 Phage Biotechnology Corporation Phage-dependent superproduction of biologically active protein and peptides
WO2004027064A2 (en) * 2002-09-18 2004-04-01 Centre Hospitalier De L'universite De Montreal (Chum) Ghrh analogues
WO2019068006A1 (en) * 2017-09-29 2019-04-04 The Charles Stark Draper Laboratory, Inc. CELLULAR LYSE CONTROLLED BY STIMULUS

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE276694C (enExample)
IN151589B (enExample) 1978-12-22 1983-05-28 Biogen Nv
CH657141A5 (de) 1980-07-01 1986-08-15 Hoffmann La Roche Dns-sequenzen, rekombinante expressionsvektoren zur mikrobiellen herstellung von human-leukozyten-interferonen und transformierte mikroorganismen.
US4775622A (en) 1982-03-08 1988-10-04 Genentech, Inc. Expression, processing and secretion of heterologous protein by yeast
CA1209501A (en) 1982-09-16 1986-08-12 Nikos Panayotatos Expression vector
JPS5979746A (ja) 1982-10-30 1984-05-09 Mitsubishi Heavy Ind Ltd 加硫機用制御装置
SU1089119A1 (ru) * 1982-11-29 1984-04-30 Институт Молекулярной Биологии И Генетики Ан Усср Способ получени @ -лактамазы
GB2143238A (en) 1983-03-31 1985-02-06 Dr Anthony Stuart Breeze A method for enzyme liberation from bacterial cells
US4637980A (en) * 1983-08-09 1987-01-20 Smithkline Beckman Corporation Externalization of products of bacteria
CA1309044C (en) 1987-11-09 1992-10-20 Toshiya Takano Method of producing foreign gene products
IL92124A (en) 1988-10-28 1996-10-31 Sidney Pestka Recombinant proteins modified to contain post-phosphorylation that do not occur in nature
US5102797A (en) 1989-05-26 1992-04-07 Dna Plant Technology Corporation Introduction of heterologous genes into bacteria using transposon flanked expression cassette and a binary vector system
US5196318A (en) 1990-06-26 1993-03-23 The Texas A&M University System Precisely regulated expression of deleterious genes
NZ314630A (en) 1991-01-17 2000-11-24 Harvard College Use of trans-splicing ribozymes for genetic modification and cell ablation in a host cell
US5346830A (en) 1991-06-11 1994-09-13 The Center For Innovative Technology Gene expression system based on regulatory elements of bateriophage P2 and satellite phage P4
US5834233A (en) 1992-04-06 1998-11-10 Gx Biosystems A/S Method of limiting the survival of genetically engineered microorganisms in their enivronment
US5622852A (en) 1994-10-31 1997-04-22 Washington University Bcl-x/Bcl-2 associated cell death regulator
US5861273A (en) 1993-12-21 1999-01-19 Celtrix Phamraceuticals, Inc. Chromosomal expression of heterologous genes in bacterial cells
US6268178B1 (en) * 1999-05-25 2001-07-31 Phage Biotechnology Corp. Phage-dependent super-production of biologically active protein and peptides
KR100861240B1 (ko) * 2000-08-15 2008-10-02 카디오배스큘러 바이오 떼러퓨틱스, 인크. 생물학적으로 활성인 인간 산성 섬유아세포 성장인자의제조방법과 맥관형성 촉진을 위한 그 용도
US6773899B2 (en) * 2000-08-15 2004-08-10 Phage Biotechnology Corporation Phage-dependent superproduction of biologically active protein and peptides

Also Published As

Publication number Publication date
DE60019411T2 (de) 2006-03-09
JP2003500059A (ja) 2003-01-07
WO2000071731A1 (en) 2000-11-30
US6268178B1 (en) 2001-07-31
AU5049100A (en) 2000-12-12
US20010044133A1 (en) 2001-11-22
US6794162B2 (en) 2004-09-21
DE60019411D1 (de) 2005-05-19
EP1180153B1 (en) 2005-04-13
EP1180153A1 (en) 2002-02-20

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