JP2003210513A - 眼科用治療装置 - Google Patents
眼科用治療装置Info
- Publication number
- JP2003210513A JP2003210513A JP2002014777A JP2002014777A JP2003210513A JP 2003210513 A JP2003210513 A JP 2003210513A JP 2002014777 A JP2002014777 A JP 2002014777A JP 2002014777 A JP2002014777 A JP 2002014777A JP 2003210513 A JP2003210513 A JP 2003210513A
- Authority
- JP
- Japan
- Prior art keywords
- electrode
- electrical stimulation
- ophthalmic treatment
- stimulation pulse
- retina
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000011282 treatment Methods 0.000 title claims abstract description 48
- 230000000638 stimulation Effects 0.000 claims abstract description 57
- 210000001525 retina Anatomy 0.000 claims abstract description 27
- 210000004087 cornea Anatomy 0.000 claims description 20
- 230000002051 biphasic effect Effects 0.000 claims description 5
- 230000034994 death Effects 0.000 abstract description 7
- 230000002207 retinal effect Effects 0.000 abstract description 3
- 210000005036 nerve Anatomy 0.000 abstract description 2
- 208000003098 Ganglion Cysts Diseases 0.000 abstract 1
- 208000005400 Synovial Cyst Diseases 0.000 abstract 1
- 238000002474 experimental method Methods 0.000 description 37
- 210000004027 cell Anatomy 0.000 description 32
- 210000003994 retinal ganglion cell Anatomy 0.000 description 17
- 230000004083 survival effect Effects 0.000 description 15
- 241000700159 Rattus Species 0.000 description 13
- 210000001328 optic nerve Anatomy 0.000 description 10
- 210000001508 eye Anatomy 0.000 description 8
- 230000030833 cell death Effects 0.000 description 7
- 239000003814 drug Substances 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 230000000052 comparative effect Effects 0.000 description 6
- 238000010586 diagram Methods 0.000 description 6
- 230000001225 therapeutic effect Effects 0.000 description 6
- 241001465754 Metazoa Species 0.000 description 5
- 229940124597 therapeutic agent Drugs 0.000 description 5
- 210000005252 bulbus oculi Anatomy 0.000 description 4
- 102000004219 Brain-derived neurotrophic factor Human genes 0.000 description 3
- 108090000715 Brain-derived neurotrophic factor Proteins 0.000 description 3
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 3
- 229940077737 brain-derived neurotrophic factor Drugs 0.000 description 3
- 230000007850 degeneration Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 229910052709 silver Inorganic materials 0.000 description 3
- 239000004332 silver Substances 0.000 description 3
- 201000004569 Blindness Diseases 0.000 description 2
- 208000010412 Glaucoma Diseases 0.000 description 2
- 241000700157 Rattus norvegicus Species 0.000 description 2
- 239000004904 UV filter Substances 0.000 description 2
- 239000007850 fluorescent dye Substances 0.000 description 2
- DVGHHMFBFOTGLM-UHFFFAOYSA-L fluorogold Chemical compound F[Au][Au]F DVGHHMFBFOTGLM-UHFFFAOYSA-L 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 210000004279 orbit Anatomy 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 210000003863 superior colliculi Anatomy 0.000 description 2
- 230000001629 suppression Effects 0.000 description 2
- 239000004129 EU approved improving agent Substances 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 108010025020 Nerve Growth Factor Proteins 0.000 description 1
- 102000007072 Nerve Growth Factors Human genes 0.000 description 1
- 208000030768 Optic nerve injury Diseases 0.000 description 1
- 201000007737 Retinal degeneration Diseases 0.000 description 1
- 206010038848 Retinal detachment Diseases 0.000 description 1
- 239000000150 Sympathomimetic Substances 0.000 description 1
- 208000034698 Vitreous haemorrhage Diseases 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001647 drug administration Methods 0.000 description 1
- 239000007772 electrode material Substances 0.000 description 1
- 238000001962 electrophoresis Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000000302 ischemic effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000003900 neurotrophic factor Substances 0.000 description 1
- 239000000734 parasympathomimetic agent Substances 0.000 description 1
- 230000001499 parasympathomimetic effect Effects 0.000 description 1
- 229940005542 parasympathomimetics Drugs 0.000 description 1
- 210000000608 photoreceptor cell Anatomy 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000004258 retinal degeneration Effects 0.000 description 1
- 230000004264 retinal detachment Effects 0.000 description 1
- 230000001975 sympathomimetic effect Effects 0.000 description 1
- 229940064707 sympathomimetics Drugs 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000004393 visual impairment Effects 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 210000004127 vitreous body Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36046—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of the eye
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
- A61N1/0543—Retinal electrodes
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Electrotherapy Devices (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002014777A JP2003210513A (ja) | 2002-01-23 | 2002-01-23 | 眼科用治療装置 |
| US10/185,003 US7020527B2 (en) | 2002-01-23 | 2002-07-01 | Ophthalmic treatment apparatus |
| US11/333,242 US7706886B2 (en) | 2002-01-23 | 2006-01-18 | Ophthalmic treatment stimulation method for inhibiting death of retinal cells |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002014777A JP2003210513A (ja) | 2002-01-23 | 2002-01-23 | 眼科用治療装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003210513A true JP2003210513A (ja) | 2003-07-29 |
| JP2003210513A5 JP2003210513A5 (enExample) | 2006-01-12 |
Family
ID=19191903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002014777A Pending JP2003210513A (ja) | 2002-01-23 | 2002-01-23 | 眼科用治療装置 |
Country Status (2)
| Country | Link |
|---|---|
| US (2) | US7020527B2 (enExample) |
| JP (1) | JP2003210513A (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011045672A (ja) * | 2009-08-28 | 2011-03-10 | Nidek Co Ltd | 眼科用電気刺激装置 |
| KR20110025691A (ko) * | 2008-06-12 | 2011-03-10 | 수프트 이탈리아 에스피에이 | 노안 및 녹내장의 예방을 위한 눈 치료 방법, 및 이러한 치료를 수행하기 위한 수단 |
| KR102431963B1 (ko) * | 2022-04-19 | 2022-08-16 | 주식회사 셀리코 | 각막 신경 자극이 가능한 콘택트 렌즈의 제조 방법 |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6427087B1 (en) * | 2000-05-04 | 2002-07-30 | Optobionics Corporation | Artificial retina device with stimulating and ground return electrodes disposed on opposite sides of the neuroretina and method of attachment |
| US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
| US20050004625A1 (en) * | 2001-06-29 | 2005-01-06 | Chow Alan Y. | Treatment of degenerative retinal disease via electrical stimulation of surface structures |
| US7031776B2 (en) * | 2001-06-29 | 2006-04-18 | Optobionics | Methods for improving damaged retinal cell function |
| US20050033202A1 (en) * | 2001-06-29 | 2005-02-10 | Chow Alan Y. | Mechanically activated objects for treatment of degenerative retinal disease |
| JP2003210513A (ja) * | 2002-01-23 | 2003-07-29 | Nidek Co Ltd | 眼科用治療装置 |
| US7321795B2 (en) * | 2003-03-24 | 2008-01-22 | Les Bogdanowicz | Compositions for electric stimulation of the eye |
| US7710923B2 (en) * | 2004-05-07 | 2010-05-04 | Interdigital Technology Corporation | System and method for implementing a media independent handover |
| ATE408432T1 (de) * | 2004-11-02 | 2008-10-15 | Sydney Biotech Pty Ltd | Extraokulare vorrichtung |
| US8103352B2 (en) * | 2004-12-03 | 2012-01-24 | Second Sight Medical Products, Inc. | Mimicking neural coding in retinal ganglion cells with short pulse electrical stimulation |
| WO2007013065A2 (en) | 2005-07-25 | 2007-02-01 | Rainbow Medical Ltd. | Electrical stimulation of blood vessels |
| DE102006021258B4 (de) * | 2006-04-28 | 2013-08-22 | Retina Implant Ag | Aktives subretinales Retina-Implantat |
| WO2008042278A2 (en) * | 2006-09-29 | 2008-04-10 | Second Sight Medical Products, Inc. | Method for measuring stable and reproducible electrode-tissue impedance |
| US8538535B2 (en) | 2010-08-05 | 2013-09-17 | Rainbow Medical Ltd. | Enhancing perfusion by contraction |
| US20100305392A1 (en) * | 2008-01-31 | 2010-12-02 | Enopace Biomedical Ltd. | Thoracic aorta and vagus nerve stimulation |
| US8626290B2 (en) | 2008-01-31 | 2014-01-07 | Enopace Biomedical Ltd. | Acute myocardial infarction treatment by electrical stimulation of the thoracic aorta |
| US9005106B2 (en) | 2008-01-31 | 2015-04-14 | Enopace Biomedical Ltd | Intra-aortic electrical counterpulsation |
| US8626299B2 (en) * | 2008-01-31 | 2014-01-07 | Enopace Biomedical Ltd. | Thoracic aorta and vagus nerve stimulation |
| RU2392910C1 (ru) * | 2008-12-25 | 2010-06-27 | Федеральное государственное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Федерального агентства по высокотехнологичной медицинской помощи" | Способ лечения хронического офтальмальгического синдрома |
| RU2406469C2 (ru) * | 2009-01-27 | 2010-12-20 | Федеральное государственное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Федерального агентства по высокотехнологичной медицинской помощи" | Способ лечения дистрофических заболеваний сетчатки и зрительного нерва |
| US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
| CA2979355C (en) | 2009-05-18 | 2023-02-21 | Dose Medical Corporation | Drug eluting ocular implant |
| US12478503B2 (en) | 2009-05-18 | 2025-11-25 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
| DE102010027201B4 (de) | 2010-01-15 | 2014-05-08 | Okuvision Gmbh | Vorrichtung zur Elektrostimulation |
| DE202010001150U1 (de) | 2010-01-15 | 2011-05-26 | Okuvision GmbH, 72770 | Vorrichtung zur Elektrostimulation |
| WO2012052912A2 (en) * | 2010-10-19 | 2012-04-26 | Bar Ilan University | Blind sight |
| US9821159B2 (en) | 2010-11-16 | 2017-11-21 | The Board Of Trustees Of The Leland Stanford Junior University | Stimulation devices and methods |
| JP2013542838A (ja) | 2010-11-16 | 2013-11-28 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | ドライアイを治療するためのシステムおよび方法 |
| EP2654715B1 (en) | 2010-11-24 | 2017-01-25 | Dose Medical Corporation | Drug eluting ocular implant |
| US8649863B2 (en) | 2010-12-20 | 2014-02-11 | Rainbow Medical Ltd. | Pacemaker with no production |
| US10245178B1 (en) | 2011-06-07 | 2019-04-02 | Glaukos Corporation | Anterior chamber drug-eluting ocular implant |
| US9526637B2 (en) | 2011-09-09 | 2016-12-27 | Enopace Biomedical Ltd. | Wireless endovascular stent-based electrodes |
| US8855783B2 (en) | 2011-09-09 | 2014-10-07 | Enopace Biomedical Ltd. | Detector-based arterial stimulation |
| US9386991B2 (en) | 2012-02-02 | 2016-07-12 | Rainbow Medical Ltd. | Pressure-enhanced blood flow treatment |
| EP2967817B1 (en) | 2013-03-12 | 2021-03-10 | Oculeve, Inc. | Implant delivery devices and systems |
| HK1220934A1 (zh) | 2013-04-19 | 2017-05-19 | Oculeve, Inc. | 鼻刺激装置和方法 |
| US20140371565A1 (en) | 2013-06-14 | 2014-12-18 | University Of Houston System | Accommodation stimulation and recording device |
| US10779965B2 (en) | 2013-11-06 | 2020-09-22 | Enopace Biomedical Ltd. | Posts with compliant junctions |
| EP3689338A1 (en) | 2014-02-25 | 2020-08-05 | Oculeve, Inc. | Polymer formulations for nasolacrimal stimulation |
| EP3677229A1 (en) | 2014-05-29 | 2020-07-08 | Glaukos Corporation | Implants with controlled drug delivery features |
| DK3171928T3 (da) | 2014-07-25 | 2020-05-18 | Oculeve Inc | Stimulationsmønstre til behandling af tørt øje |
| WO2016065215A1 (en) | 2014-10-22 | 2016-04-28 | Oculeve, Inc. | Stimulation devices and methods for treating dry eye |
| AU2015335772B2 (en) | 2014-10-22 | 2020-07-09 | Oculeve, Inc. | Contact lens for increasing tear production |
| WO2017040853A1 (en) | 2015-09-02 | 2017-03-09 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
| WO2017053885A1 (en) | 2015-09-25 | 2017-03-30 | Glaukos Corporation | Punctal implants with controlled drug delivery features and methods of using same |
| US10426958B2 (en) | 2015-12-04 | 2019-10-01 | Oculeve, Inc. | Intranasal stimulation for enhanced release of ocular mucins and other tear proteins |
| US10252048B2 (en) | 2016-02-19 | 2019-04-09 | Oculeve, Inc. | Nasal stimulation for rhinitis, nasal congestion, and ocular allergies |
| CN115120405A (zh) | 2016-04-20 | 2022-09-30 | 多斯医学公司 | 生物可吸收眼部药物的递送装置 |
| WO2017192572A1 (en) | 2016-05-02 | 2017-11-09 | Oculeve, Inc. | Intranasal stimulation for treatment of meibomian gland disease and blepharitis |
| US11400299B1 (en) | 2021-09-14 | 2022-08-02 | Rainbow Medical Ltd. | Flexible antenna for stimulator |
| CN115645739A (zh) * | 2022-12-26 | 2023-01-31 | 中国中医科学院眼科医院 | 一种中药组合物微电流刺激装置及其使用方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4232680A (en) * | 1978-05-16 | 1980-11-11 | Hudleson Bruce D | Apparatus and method for transcutaneous electrotherapy nerve stimulator |
| US4603697A (en) * | 1985-01-07 | 1986-08-05 | William Kamerling | System for preventing or treating open angle glaucoma and presbyopia |
| EP0325201A3 (de) | 1988-01-20 | 1990-01-31 | Etama Ag | Stimulationsgerät zur Verbesserung des Sehvermögens des Sehbehinderten |
| US4955378A (en) * | 1988-05-02 | 1990-09-11 | University Of South Florida | Apparatus and methods for performing electrofusion at specific anatomical sites |
| RU1799577C (ru) * | 1989-08-17 | 1993-03-07 | Межотраслевой научно-технический комплекс "Микрохирургия глаза" | Способ улучшени зрительных функций при заболевани х зрительного нерва и сетчатки и устройство дл его осуществлени |
| US5522864A (en) * | 1994-10-25 | 1996-06-04 | Wallace; Larry B. | Apparatus and method for ocular treatment |
| JPH08154897A (ja) | 1994-12-01 | 1996-06-18 | Kyoto Contact Lens Kk | 光源一体型コンタクトレンズ電極 |
| US5895415A (en) * | 1995-06-06 | 1999-04-20 | Optobionics Corporation | Multi-phasic microphotodiode retinal implant and adaptive imaging retinal stimulation system |
| JPH09266954A (ja) | 1996-04-03 | 1997-10-14 | Meiwa Shoji Kk | 電極付治療器具 |
| JP2000024122A (ja) | 1998-07-08 | 2000-01-25 | Uchiike Masahiro | 眼窩用マイクロアンペア治療装置 |
| US6101411A (en) * | 1998-09-24 | 2000-08-08 | Newsome; David A. | Dilation enhancer |
| US20040106965A1 (en) * | 2001-06-29 | 2004-06-03 | Chow Alan Y. | Methods and apparatus for treatment of degenerative retinal disease via indirect electrical stimulation |
| US7003355B1 (en) * | 2001-11-20 | 2006-02-21 | Suaning Gregg J | Vision prosthesis for the blind and method for implementing same |
| JP2003210513A (ja) * | 2002-01-23 | 2003-07-29 | Nidek Co Ltd | 眼科用治療装置 |
| US7142909B2 (en) * | 2002-04-11 | 2006-11-28 | Second Sight Medical Products, Inc. | Biocompatible bonding method and electronics package suitable for implantation |
-
2002
- 2002-01-23 JP JP2002014777A patent/JP2003210513A/ja active Pending
- 2002-07-01 US US10/185,003 patent/US7020527B2/en not_active Expired - Fee Related
-
2006
- 2006-01-18 US US11/333,242 patent/US7706886B2/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20110025691A (ko) * | 2008-06-12 | 2011-03-10 | 수프트 이탈리아 에스피에이 | 노안 및 녹내장의 예방을 위한 눈 치료 방법, 및 이러한 치료를 수행하기 위한 수단 |
| JP2011522662A (ja) * | 2008-06-12 | 2011-08-04 | ソーフト イタリア エスピーエー | 老眼および緑内障予防のための眼の治療方法およびこの治療を実行するための手段 |
| KR101675169B1 (ko) * | 2008-06-12 | 2016-11-10 | 수프트 이탈리아 에스피에이 | 노안 및 녹내장의 예방을 위한 방법, 및 이러한 처치를 수행하기 위한 수단 |
| JP2011045672A (ja) * | 2009-08-28 | 2011-03-10 | Nidek Co Ltd | 眼科用電気刺激装置 |
| KR102431963B1 (ko) * | 2022-04-19 | 2022-08-16 | 주식회사 셀리코 | 각막 신경 자극이 가능한 콘택트 렌즈의 제조 방법 |
Also Published As
| Publication number | Publication date |
|---|---|
| US7020527B2 (en) | 2006-03-28 |
| US7706886B2 (en) | 2010-04-27 |
| US20030139784A1 (en) | 2003-07-24 |
| US20060116740A1 (en) | 2006-06-01 |
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