JP2003061662A5 - - Google Patents

Info

Publication number

JP2003061662A5

JP2003061662A5 JP2001240947A JP2001240947A JP2003061662A5 JP 2003061662 A5 JP2003061662 A5 JP 2003061662A5 JP 2001240947 A JP2001240947 A JP 2001240947A JP 2001240947 A JP2001240947 A JP 2001240947A JP 2003061662 A5 JP2003061662 A5 JP 2003061662A5

Authority

JP

Japan

Prior art keywords

protein

salt

seq

amino acid

acid sequence

Prior art date

2001-08-08

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
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• 108090000623 proteins and genes Proteins 0.000 description 22
• 102000004169 proteins and genes Human genes 0.000 description 22
• 150000003839 salts Chemical class 0.000 description 19
• 125000003275 alpha amino acid group Chemical group 0.000 description 12
• 108090000765 processed proteins & peptides Proteins 0.000 description 12
• 230000000694 effects Effects 0.000 description 7
• 108090000371 Esterases Proteins 0.000 description 5
• 239000002157 polynucleotide Substances 0.000 description 5
• 102000040430 polynucleotide Human genes 0.000 description 5
• 108091033319 polynucleotide Proteins 0.000 description 5
• 206010003210 Arteriosclerosis Diseases 0.000 description 2
• 208000031226 Hyperlipidaemia Diseases 0.000 description 2
• 208000008589 Obesity Diseases 0.000 description 2
• 208000011775 arteriosclerosis disease Diseases 0.000 description 2
• 239000003795 chemical substances by application Substances 0.000 description 2
• 150000001875 compounds Chemical class 0.000 description 2
• 206010012601 diabetes mellitus Diseases 0.000 description 2
• 239000000032 diagnostic agent Substances 0.000 description 2
• 229940039227 diagnostic agent Drugs 0.000 description 2
• 239000003814 drug Substances 0.000 description 2
• 239000002773 nucleotide Substances 0.000 description 2
• 125000003729 nucleotide group Chemical group 0.000 description 2
• 235000020824 obesity Nutrition 0.000 description 2
• 238000012216 screening Methods 0.000 description 2
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 1
• 238000012258 culturing Methods 0.000 description 1
• 230000002401 inhibitory effect Effects 0.000 description 1
• 238000000034 method Methods 0.000 description 1
• 230000001737 promoting effect Effects 0.000 description 1