JP2002530354A - 移植の拒絶反応の出現の処置に使用するためのｃｄ２５結合分子 - Google Patents

移植の拒絶反応の出現の処置に使用するためのｃｄ２５結合分子

Info

Publication number
JP2002530354A
JP2002530354A JP2000583562A JP2000583562A JP2002530354A JP 2002530354 A JP2002530354 A JP 2002530354A JP 2000583562 A JP2000583562 A JP 2000583562A JP 2000583562 A JP2000583562 A JP 2000583562A JP 2002530354 A JP2002530354 A JP 2002530354A
Authority
JP
Japan
Prior art keywords
monoclonal antibody
antibody specific
recipient
effective amount
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000583562A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002530354A5 (https=
Inventor
ジル・フートラン
リチャード・ケイ・ハウエル
ペーター・マルバッハ
アンドリュー・ロバーツ
マックス・ハー・シュライアー
マンフレート・シュルツ
Original Assignee
ノバルティス アクチエンゲゼルシャフト
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ノバルティス アクチエンゲゼルシャフト filed Critical ノバルティス アクチエンゲゼルシャフト
Publication of JP2002530354A publication Critical patent/JP2002530354A/ja
Publication of JP2002530354A5 publication Critical patent/JP2002530354A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2000583562A 1998-11-23 1999-11-22 移植の拒絶反応の出現の処置に使用するためのｃｄ２５結合分子 Pending JP2002530354A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9825632.4A GB9825632D0 (en) 1998-11-23 1998-11-23 Organic compounds
GB9825632.4 1998-11-23
PCT/EP1999/008988 WO2000030679A1 (en) 1998-11-23 1999-11-22 Cd25 binding molecules for use in the treatment of manifestations of rejection in transplantation

Publications (2)

Publication Number Publication Date
JP2002530354A true JP2002530354A (ja) 2002-09-17
JP2002530354A5 JP2002530354A5 (https=) 2007-01-11

Family

ID=10842889

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000583562A Pending JP2002530354A (ja) 1998-11-23 1999-11-22 移植の拒絶反応の出現の処置に使用するためのｃｄ２５結合分子

Country Status (6)

Country Link
US (2) US20010041179A1 (https=)
EP (1) EP1131098A1 (https=)
JP (1) JP2002530354A (https=)
AU (1) AU1384600A (https=)
GB (1) GB9825632D0 (https=)
WO (1) WO2000030679A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007536431A (ja) * 2004-05-06 2007-12-13 キャボット　コーポレイション スパッタターゲット及び回転軸方向鍛造によるその形成方法

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7438907B2 (en) 2002-11-15 2008-10-21 Genmab A/S Human monoclonal antibodies against CD25
US10610104B2 (en) 2016-12-07 2020-04-07 Progenity, Inc. Gastrointestinal tract detection methods, devices and systems
US20210138213A1 (en) 2017-03-30 2021-05-13 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device
WO2019246312A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immunomodulator
US12227565B2 (en) 2018-06-20 2025-02-18 Biora Therapeutics, Inc. Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine
US20220249814A1 (en) 2018-11-19 2022-08-11 Progenity, Inc. Methods and devices for treating a disease with biotherapeutics
CN121197633A (zh) 2019-12-13 2025-12-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3815472A1 (de) * 1988-05-06 1989-11-16 Centre Regional De Transfusion Monoklonaler antikoerper und seine verwendung
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
HUT60768A (en) 1990-03-16 1992-10-28 Sandoz Ag Process for producing cd25 fixing molecules
JPH05244982A (ja) * 1991-12-06 1993-09-24 Sumitomo Chem Co Ltd 擬人化ｂ−ｂ１０
US5428040A (en) * 1993-08-31 1995-06-27 The Du Pont Merck Pharmaceutical Company Carbocyclic fused-ring quinolinecarboxylic acids useful as immunosuppressive agents
EP1208847B8 (en) * 1996-07-30 2007-02-14 Novartis AG Pharmaceutical compositions for the treatment of transplant rejection, as well as autoimmune or inflammatory conditions
US6013256A (en) * 1996-09-24 2000-01-11 Protein Design Labs, Inc. Method of preventing acute rejection following solid organ transplantation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007536431A (ja) * 2004-05-06 2007-12-13 キャボット　コーポレイション スパッタターゲット及び回転軸方向鍛造によるその形成方法

Also Published As

Publication number Publication date
US20010041179A1 (en) 2001-11-15
US20080286281A1 (en) 2008-11-20
EP1131098A1 (en) 2001-09-12
WO2000030679A1 (en) 2000-06-02
GB9825632D0 (en) 1999-01-13
AU1384600A (en) 2000-06-13

Similar Documents

Publication Publication Date Title
US6013256A (en) Method of preventing acute rejection following solid organ transplantation
CN113924318A (zh) 具有抗BCMA抗体和gamma分泌酶抑制剂的联合疗法
JP2002502824A (ja) 同種移植における補刺激遮断および混合キメラ現象
MXPA05012965A (es) Uso de inhibidores de miostatina (gdf8) en conjuncion con corticoesteroides para el tratamiento de desordenes neuromusculares y composiciones farmaceuticas para ello.
JP2002500648A (ja) 反適応性の免疫応答、特に移植片拒絶を防ぐためのｃｄ４０：ｃｄ１５４結合妨害剤の使用
US20080286281A1 (en) Cd25 binding molecules for the use in the treatment of manifestations of rejection in transplantation
JP2021130668A (ja) 多発性骨髄腫（ｍｍ）の処置
JP2021525735A (ja) 抗ｃｄ３７免疫コンジュゲート投薬レジメン
EP3478713B1 (en) Compositions for treating amyloidosis
EP0680336A1 (fr) Anticorps monoclonaux anti-lfa-1 pour la preparation d'un medicament destine a prevenir le rejet des greffes d'organes
EP4442702A1 (en) Method for treating myasthenia gravis with taci-fc fusion protein
JP2003528890A (ja) 胃腸管の炎症性疾患の処置におけるｃｄ２５結合分子の使用
JP2024525870A (ja) 抗ｐｌａ２ｒ自己抗体媒介膜性腎症の治療
CA3123024A1 (en) Compositions and methods for enhancing body weight and lean muscle mass using antagonists against leptin receptor, gdf8 and activin a
US20250011417A1 (en) Methods for the treatment of thyroid eye disease
JP2002530354A5 (https=)
CA3204187A1 (en) Anti-cd38 antibodies and their uses
TW202120546A (zh) 使用介白素-17（il-17）拮抗劑治療狼瘡性腎炎之方法
CN112773802B (zh) 一种化合物用于预防或治疗移植物抗宿主病的用途
JP3973360B2 (ja) 関節リウマチまたは皮膚疾患の処置に使用するためのｃｄ２５結合分子
JP2024517796A (ja) 抗ｂａｆｆｒ抗体を使用するループス腎炎の治療
CN114728046A (zh) 联合抗cd30 adc、抗pd-1和化疗以治疗血液癌症
HK40077034A (en) Combination anti-cd30 adc, anti-pd-1 and chemotherapeutic for treatment of hematopoietic cancers
WO2023230554A1 (en) Combination of a braf inhibitor, an egfr inhibitor, and a pd-1 antagonist for the treatment of braf v600e-mutant, msi-h/dmmr colorectal cancer
CN118076640A (zh) 抗-pla2r自身抗体介导的膜性肾病的治疗

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20061109

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20061109

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100202

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100506

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20110426