JP2002530112A5 - - Google Patents
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- Publication number
- JP2002530112A5 JP2002530112A5 JP2000584082A JP2000584082A JP2002530112A5 JP 2002530112 A5 JP2002530112 A5 JP 2002530112A5 JP 2000584082 A JP2000584082 A JP 2000584082A JP 2000584082 A JP2000584082 A JP 2000584082A JP 2002530112 A5 JP2002530112 A5 JP 2002530112A5
- Authority
- JP
- Japan
- Prior art keywords
- cam
- enzyme
- amino acid
- electron transfer
- reductase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 description 17
- 101150053185 P450 gene Proteins 0.000 description 6
- 102000004190 Enzymes Human genes 0.000 description 5
- 108090000790 Enzymes Proteins 0.000 description 5
- 230000027756 respiratory electron transport chain Effects 0.000 description 5
- -1 cyclic terpene Chemical class 0.000 description 4
- 239000012634 fragment Substances 0.000 description 4
- 230000035772 mutation Effects 0.000 description 4
- 239000002253 acid Substances 0.000 description 3
- 150000001413 amino acids Chemical class 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 125000002015 acyclic group Chemical group 0.000 description 1
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
- 150000001925 cycloalkenes Chemical class 0.000 description 1
- 108020001507 fusion proteins Proteins 0.000 description 1
- 102000037865 fusion proteins Human genes 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 102200128618 rs397508403 Human genes 0.000 description 1
- 102220020518 rs397508403 Human genes 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9825421.2 | 1998-11-19 | ||
| GBGB9825421.2A GB9825421D0 (en) | 1998-11-19 | 1998-11-19 | Process for oxidising terpenes |
| PCT/GB1999/003873 WO2000031273A2 (en) | 1998-11-19 | 1999-11-19 | Process for oxidising terpenes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011184705A Division JP5611151B2 (ja) | 1998-11-19 | 2011-08-26 | テルペン類を酸化する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002530112A JP2002530112A (ja) | 2002-09-17 |
| JP2002530112A5 true JP2002530112A5 (enExample) | 2007-01-11 |
| JP4886930B2 JP4886930B2 (ja) | 2012-02-29 |
Family
ID=10842737
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000584082A Expired - Lifetime JP4886930B2 (ja) | 1998-11-19 | 1999-11-19 | テルペン類を酸化する方法 |
| JP2011184705A Expired - Lifetime JP5611151B2 (ja) | 1998-11-19 | 2011-08-26 | テルペン類を酸化する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011184705A Expired - Lifetime JP5611151B2 (ja) | 1998-11-19 | 2011-08-26 | テルペン類を酸化する方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7211420B1 (enExample) |
| EP (1) | EP1131440B1 (enExample) |
| JP (2) | JP4886930B2 (enExample) |
| AT (1) | ATE510021T1 (enExample) |
| AU (1) | AU1281900A (enExample) |
| GB (1) | GB9825421D0 (enExample) |
| WO (1) | WO2000031273A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9914373D0 (en) | 1999-06-18 | 1999-08-18 | Isis Innovation | Process for oxidising aromatic compounds |
| CA2379518A1 (en) | 1999-07-27 | 2001-02-01 | Basf Aktiengesellschaft | Electron donor system for enzymes and its use for the biochemical conversion of substrates |
| MY126592A (en) * | 1999-07-27 | 2006-10-31 | Basf Ag | Novel cytochrome p450 monooxygenases and their use for the oxidation of organic compounds |
| GB0002201D0 (en) * | 2000-01-31 | 2000-03-22 | Imperial College | Process |
| EP1470219A4 (en) | 2001-04-16 | 2005-10-05 | California Inst Of Techn | PEROXIDE MOLDED CYTOCHROME OXYGENASE P450 OXYGENASE VARIANTS |
| WO2003008563A2 (en) | 2001-07-20 | 2003-01-30 | California Institute Of Technology | Improved cytochrome p450 oxygenases |
| WO2005017105A2 (en) | 2003-06-17 | 2005-02-24 | California University Of Technology | Regio- and enantioselective alkane hydroxylation with modified cytochrome p450 |
| DK1660646T3 (en) | 2003-08-11 | 2015-03-09 | California Inst Of Techn | Thermostable peroxide-driven cytochrome P450 oxygenase variants and methods of use |
| US11214817B2 (en) | 2005-03-28 | 2022-01-04 | California Institute Of Technology | Alkane oxidation by modified hydroxylases |
| US8715988B2 (en) | 2005-03-28 | 2014-05-06 | California Institute Of Technology | Alkane oxidation by modified hydroxylases |
| US8026085B2 (en) | 2006-08-04 | 2011-09-27 | California Institute Of Technology | Methods and systems for selective fluorination of organic molecules |
| US8252559B2 (en) | 2006-08-04 | 2012-08-28 | The California Institute Of Technology | Methods and systems for selective fluorination of organic molecules |
| WO2008073498A2 (en) * | 2006-12-12 | 2008-06-19 | The Regents Of The University Of California | Artemisinic epoxide and methods for producing same |
| US8802401B2 (en) | 2007-06-18 | 2014-08-12 | The California Institute Of Technology | Methods and compositions for preparation of selectively protected carbohydrates |
| GB0719620D0 (en) * | 2007-10-08 | 2007-11-14 | Isis Innovation | Mutant Enzymes |
| WO2010019489A2 (en) * | 2008-08-13 | 2010-02-18 | Salk Institute For Biological Studies | Method for making terpene derivatives |
| WO2013016207A2 (en) | 2011-07-22 | 2013-01-31 | California Institute Of Technology | Stable fungal cel6 enzyme variants |
| RU2625224C2 (ru) * | 2011-11-01 | 2017-07-12 | Фирмениш Са | Цитохром p450 и его применение для энзиматического окисления терпенов |
| JP6435261B2 (ja) * | 2012-08-31 | 2018-12-05 | ノバルティス アーゲー | Staphylococcusaureusに対する免疫化のための安定化されたタンパク質 |
| KR20160138283A (ko) * | 2014-03-31 | 2016-12-02 | 베링거잉겔하임베트메디카게엠베하 | 개선된 모듈러 항원 운반 분자 및 이의 용도 |
| CN107002109A (zh) | 2014-08-21 | 2017-08-01 | 马努斯生物合成股份有限公司 | 含氧萜烯的生产方法 |
| EP3297442A4 (en) | 2015-05-18 | 2018-11-07 | Zymtronix, LLC | Magnetically immobilized microbiocidal enzymes |
| CN109788762B (zh) | 2016-08-13 | 2023-07-11 | 齐姆特罗尼克斯催化系统股份有限公司 | 磁性固定化的杀生物酶和杀生物化学品 |
| WO2018102319A1 (en) * | 2016-12-03 | 2018-06-07 | Zymtronix Catalytic Systems, Inc. | Magnetically immobilized metabolic enzymes and cofactor systems |
| EP3858986A1 (en) | 2020-02-03 | 2021-08-04 | Bayer Aktiengesellschaft | P450 bm3 monooxygenase variants for c19-hydroxylation of steroids |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB334841A (en) | 1929-06-04 | 1930-09-04 | John Pinder | Theft alarm or signal for use on motor vehicles |
| DE3629890A1 (de) | 1986-08-29 | 1988-03-10 | Schering Ag | Mikroorganismen und plasmide fuer die 2,4-dichlorphenoxyessigsaeure (2,4-d)-monooxigenase - bildung und verfahren zur herstellung dieser plasmide und staemme |
| FR2693207B1 (fr) | 1992-07-03 | 1994-09-30 | Orsan | Souche de levure permettant la co-expression d'une activité mono-oxygénase de cytochrome P450 hétérologue et d'une NADPH-cytochrome P450-réductase endogène ou hétérologue et son utilisation à des fins de bioconversion. |
| GB9422205D0 (en) * | 1994-11-03 | 1994-12-21 | British Gas Plc | Enzyme mutant and method |
| EP0906431A1 (en) * | 1995-11-01 | 1999-04-07 | BG plc | MUTANT MONO-OXYGENASE CYTOCHROME P450cam |
| WO1997016553A1 (en) | 1995-11-01 | 1997-05-09 | Bg Plc | MUTANT MONO-OXYGENASE CYTOCHROME P450cam |
| US5763237A (en) | 1996-05-21 | 1998-06-09 | Board Of Trustees Operating Michigan State University | Method for production of monoterpene derivatives of limonene |
-
1998
- 1998-11-19 GB GBGB9825421.2A patent/GB9825421D0/en not_active Ceased
-
1999
- 1999-11-19 AU AU12819/00A patent/AU1281900A/en not_active Abandoned
- 1999-11-19 EP EP99956167A patent/EP1131440B1/en not_active Expired - Lifetime
- 1999-11-19 JP JP2000584082A patent/JP4886930B2/ja not_active Expired - Lifetime
- 1999-11-19 WO PCT/GB1999/003873 patent/WO2000031273A2/en not_active Ceased
- 1999-11-19 US US09/856,339 patent/US7211420B1/en not_active Expired - Lifetime
- 1999-11-19 AT AT99956167T patent/ATE510021T1/de not_active IP Right Cessation
-
2011
- 2011-08-26 JP JP2011184705A patent/JP5611151B2/ja not_active Expired - Lifetime
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