JP2002526455A - 治療用たんぱく質に対する免疫応答を下方変調する方法 - Google Patents
治療用たんぱく質に対する免疫応答を下方変調する方法Info
- Publication number
- JP2002526455A JP2002526455A JP2000573762A JP2000573762A JP2002526455A JP 2002526455 A JP2002526455 A JP 2002526455A JP 2000573762 A JP2000573762 A JP 2000573762A JP 2000573762 A JP2000573762 A JP 2000573762A JP 2002526455 A JP2002526455 A JP 2002526455A
- Authority
- JP
- Japan
- Prior art keywords
- agent
- antibody
- factor viii
- cells
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15817898A | 1998-09-21 | 1998-09-21 | |
US09/158,178 | 1998-09-21 | ||
PCT/US1999/021991 WO2000016801A1 (en) | 1998-09-21 | 1999-09-21 | Methods of downmodulating the immune response to therapeutic proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2002526455A true JP2002526455A (ja) | 2002-08-20 |
Family
ID=22566971
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000573762A Withdrawn JP2002526455A (ja) | 1998-09-21 | 1999-09-21 | 治療用たんぱく質に対する免疫応答を下方変調する方法 |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP1115423A1 (ko) |
JP (1) | JP2002526455A (ko) |
KR (1) | KR20010085830A (ko) |
CN (1) | CN1331602A (ko) |
AU (1) | AU761206B2 (ko) |
BR (1) | BR9913991A (ko) |
CA (1) | CA2343916A1 (ko) |
CZ (1) | CZ20011021A3 (ko) |
EA (1) | EA005236B1 (ko) |
HK (1) | HK1039059A1 (ko) |
HU (1) | HUP0103960A3 (ko) |
IL (1) | IL142069A0 (ko) |
LT (1) | LT4920B (ko) |
LV (1) | LV12768B (ko) |
MX (1) | MXPA01002898A (ko) |
NO (1) | NO20011412L (ko) |
NZ (1) | NZ511034A (ko) |
PL (1) | PL346796A1 (ko) |
SI (1) | SI20626A (ko) |
WO (1) | WO2000016801A1 (ko) |
ZA (1) | ZA200103156B (ko) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20180006390A (ko) * | 2015-05-11 | 2018-01-17 | 해모스타틱스 리미티드 | 지혈 조성물 |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5397703A (en) | 1992-07-09 | 1995-03-14 | Cetus Oncology Corporation | Method for generation of antibodies to cell surface molecules |
WO2001089564A2 (en) * | 2000-05-19 | 2001-11-29 | The Center For Blood Research, Inc. | Methods for diagnosing and treating hemostatic disorders by modulating p-selectin activity |
JP2007516509A (ja) * | 2003-06-10 | 2007-06-21 | スミスズ ディテクション インコーポレイティド | センサ装置 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5171569A (en) | 1985-03-15 | 1992-12-15 | National Research Development Corporation | Factor IX preparations uncontaminated by plasma components or pox virus |
JPH0788399B2 (ja) | 1985-04-12 | 1995-09-27 | ジェネティックス・インスチチュ−ト・インコ−ポレ−テッド | 新規プロコアギュラント蛋白質 |
US5422260A (en) | 1986-05-29 | 1995-06-06 | Genetics Institute, Inc. -Legal Affairs | Human factor VIII:c muteins |
US4994371A (en) | 1987-08-28 | 1991-02-19 | Davie Earl W | DNA preparation of Christmas factor and use of DNA sequences |
FR2657884B1 (fr) | 1990-02-05 | 1994-09-02 | Tm Innovation | Procede pour la preparation du facteur viii humain et d'analogues du facteur viii. |
US5661008A (en) | 1991-03-15 | 1997-08-26 | Kabi Pharmacia Ab | Recombinant human factor VIII derivatives |
US5770197A (en) | 1991-06-27 | 1998-06-23 | Bristol-Myers Squibb Company | Methods for regulating the immune response using B7 binding molecules and IL4-binding molecules |
JP3722375B2 (ja) | 1991-06-27 | 2005-11-30 | ブリストル−マイヤーズ スクイブ カンパニー | Ctla4レセプター、それを含有する融合タンパク質およびそれらの使用 |
WO1993009804A1 (en) | 1991-11-18 | 1993-05-27 | The Scripps Research Institute | Serine protease derived-polypeptides and anti-peptide antibodies, systems and therapeutic methods for inhibiting coagulation |
US5744446A (en) | 1992-04-07 | 1998-04-28 | Emory University | Hybrid human/animal factor VIII |
US5364771A (en) | 1992-04-07 | 1994-11-15 | Emory University | Hybrid human/porcine factor VIII |
US5663060A (en) | 1992-04-07 | 1997-09-02 | Emory University | Hybrid human/animal factor VIII |
US5621039A (en) | 1993-06-08 | 1997-04-15 | Hallahan; Terrence W. | Factor IX- polymeric conjugates |
EP0776217A1 (en) * | 1994-08-19 | 1997-06-04 | Novo Nordisk A/S | A method of treating a patient with a biologically active compound |
EP0804076A4 (en) * | 1994-10-19 | 1998-10-21 | Genetic Therapy Inc | GENTHERAPY THROUGH SIMULTANEOUS AND REPEATED ADMINISTRATION OF ADENOVIRUS AND IMMUNE SUPPRESSIVES |
US5714583A (en) | 1995-06-07 | 1998-02-03 | Genetics Institute, Inc. | Factor IX purification methods |
US5916560A (en) * | 1996-03-20 | 1999-06-29 | Bristol-Myers Squibb Company | Methods for inhibiting an immune response by blocking the GP39/CD40 and CTLA4/CD28/B7 pathways and compositions for use therewith |
BR9807471A (pt) * | 1997-01-10 | 2000-03-21 | Biogen Inc | Uso do composto anti-cd40l |
BR9810755A (pt) * | 1997-06-20 | 2000-08-15 | Biogen Inc | Terapia de bloqueio de cd 154 para a sìndrome inibidora de proteìna terapêutica |
US8151477B2 (en) | 2009-11-06 | 2012-04-10 | Hexagon Metrology Ab | CMM with modular functionality |
-
1999
- 1999-09-21 NZ NZ511034A patent/NZ511034A/xx unknown
- 1999-09-21 IL IL14206999A patent/IL142069A0/xx unknown
- 1999-09-21 CA CA002343916A patent/CA2343916A1/en not_active Abandoned
- 1999-09-21 EA EA200100385A patent/EA005236B1/ru not_active IP Right Cessation
- 1999-09-21 MX MXPA01002898A patent/MXPA01002898A/es unknown
- 1999-09-21 WO PCT/US1999/021991 patent/WO2000016801A1/en not_active Application Discontinuation
- 1999-09-21 SI SI9920084A patent/SI20626A/sl not_active IP Right Cessation
- 1999-09-21 KR KR1020017003611A patent/KR20010085830A/ko not_active Application Discontinuation
- 1999-09-21 CN CN99813510A patent/CN1331602A/zh active Pending
- 1999-09-21 EP EP99969339A patent/EP1115423A1/en not_active Withdrawn
- 1999-09-21 PL PL99346796A patent/PL346796A1/xx not_active Application Discontinuation
- 1999-09-21 CZ CZ20011021A patent/CZ20011021A3/cs unknown
- 1999-09-21 JP JP2000573762A patent/JP2002526455A/ja not_active Withdrawn
- 1999-09-21 AU AU60578/99A patent/AU761206B2/en not_active Ceased
- 1999-09-21 HU HU0103960A patent/HUP0103960A3/hu unknown
- 1999-09-21 BR BR9913991-0A patent/BR9913991A/pt not_active IP Right Cessation
-
2001
- 2001-03-20 NO NO20011412A patent/NO20011412L/no not_active Application Discontinuation
- 2001-04-18 ZA ZA200103156A patent/ZA200103156B/xx unknown
- 2001-04-20 LT LT2001045A patent/LT4920B/lt not_active IP Right Cessation
- 2001-04-20 LV LVP-01-62A patent/LV12768B/lv unknown
-
2002
- 2002-01-10 HK HK02100157.7A patent/HK1039059A1/zh unknown
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20180006390A (ko) * | 2015-05-11 | 2018-01-17 | 해모스타틱스 리미티드 | 지혈 조성물 |
JP2018515216A (ja) * | 2015-05-11 | 2018-06-14 | ハエモスタティクス リミテッド | 止血組成物 |
KR102645212B1 (ko) | 2015-05-11 | 2024-03-07 | 해모스타틱스 리미티드 | 지혈 조성물 |
Also Published As
Publication number | Publication date |
---|---|
WO2000016801A1 (en) | 2000-03-30 |
EP1115423A1 (en) | 2001-07-18 |
CN1331602A (zh) | 2002-01-16 |
HUP0103960A3 (en) | 2003-09-29 |
LV12768A (en) | 2001-12-20 |
EA200100385A1 (ru) | 2001-10-22 |
NZ511034A (en) | 2004-03-26 |
LT4920B (lt) | 2002-06-25 |
HK1039059A1 (zh) | 2002-04-12 |
AU761206B2 (en) | 2003-05-29 |
WO2000016801A9 (en) | 2000-10-26 |
BR9913991A (pt) | 2001-07-03 |
LT2001045A (en) | 2002-01-25 |
PL346796A1 (en) | 2002-02-25 |
ZA200103156B (en) | 2002-07-18 |
KR20010085830A (ko) | 2001-09-07 |
NO20011412D0 (no) | 2001-03-20 |
SI20626A (sl) | 2002-02-28 |
HUP0103960A2 (hu) | 2002-02-28 |
MXPA01002898A (es) | 2002-06-04 |
IL142069A0 (en) | 2002-03-10 |
AU6057899A (en) | 2000-04-10 |
LV12768B (lv) | 2002-06-20 |
CZ20011021A3 (cs) | 2001-10-17 |
CA2343916A1 (en) | 2000-03-30 |
NO20011412L (no) | 2001-05-16 |
EA005236B1 (ru) | 2004-12-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A300 | Application deemed to be withdrawn because no request for examination was validly filed |
Free format text: JAPANESE INTERMEDIATE CODE: A300 Effective date: 20061205 |