NZ511034A - Methods of downmodulating the immune response to therapeutic proteins - Google Patents

Methods of downmodulating the immune response to therapeutic proteins

Info

Publication number
NZ511034A
NZ511034A NZ511034A NZ51103499A NZ511034A NZ 511034 A NZ511034 A NZ 511034A NZ 511034 A NZ511034 A NZ 511034A NZ 51103499 A NZ51103499 A NZ 51103499A NZ 511034 A NZ511034 A NZ 511034A
Authority
NZ
New Zealand
Prior art keywords
immune response
downmodulating
methods
therapeutic proteins
composition
Prior art date
Application number
NZ511034A
Other languages
English (en)
Inventor
Jiahua Qian
Leon W Hoyer
Mary Collins
Gary Gray
Original Assignee
American Nat Red Cross
Inst Genetics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Nat Red Cross, Inst Genetics Llc filed Critical American Nat Red Cross
Publication of NZ511034A publication Critical patent/NZ511034A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • A61K38/37Factors VIII
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4846Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NZ511034A 1998-09-21 1999-09-21 Methods of downmodulating the immune response to therapeutic proteins NZ511034A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15817898A 1998-09-21 1998-09-21
PCT/US1999/021991 WO2000016801A1 (en) 1998-09-21 1999-09-21 Methods of downmodulating the immune response to therapeutic proteins

Publications (1)

Publication Number Publication Date
NZ511034A true NZ511034A (en) 2004-03-26

Family

ID=22566971

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ511034A NZ511034A (en) 1998-09-21 1999-09-21 Methods of downmodulating the immune response to therapeutic proteins

Country Status (21)

Country Link
EP (1) EP1115423A1 (xx)
JP (1) JP2002526455A (xx)
KR (1) KR20010085830A (xx)
CN (1) CN1331602A (xx)
AU (1) AU761206B2 (xx)
BR (1) BR9913991A (xx)
CA (1) CA2343916A1 (xx)
CZ (1) CZ20011021A3 (xx)
EA (1) EA005236B1 (xx)
HK (1) HK1039059A1 (xx)
HU (1) HUP0103960A3 (xx)
IL (1) IL142069A0 (xx)
LT (1) LT4920B (xx)
LV (1) LV12768B (xx)
MX (1) MXPA01002898A (xx)
NO (1) NO20011412L (xx)
NZ (1) NZ511034A (xx)
PL (1) PL346796A1 (xx)
SI (1) SI20626A (xx)
WO (1) WO2000016801A1 (xx)
ZA (1) ZA200103156B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5397703A (en) 1992-07-09 1995-03-14 Cetus Oncology Corporation Method for generation of antibodies to cell surface molecules
EP1289552B1 (en) * 2000-05-19 2006-03-29 The Center for Blood Research, INC. Methods for treating hemostatic disorders by soluble p-selectin
EP1636579A4 (en) * 2003-06-10 2011-10-05 Smiths Detection Inc SENSOR ASSEMBLY
GB201508024D0 (en) 2015-05-11 2015-06-24 Haemostatix Ltd Haemostatic compositions

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171569A (en) 1985-03-15 1992-12-15 National Research Development Corporation Factor IX preparations uncontaminated by plasma components or pox virus
CA1341174C (en) 1985-04-12 2001-01-30 John J. Toole Jr. Procoagulant proteins derived from factor viii: c
US5422260A (en) 1986-05-29 1995-06-06 Genetics Institute, Inc. -Legal Affairs Human factor VIII:c muteins
US4994371A (en) 1987-08-28 1991-02-19 Davie Earl W DNA preparation of Christmas factor and use of DNA sequences
FR2657884B1 (fr) 1990-02-05 1994-09-02 Tm Innovation Procede pour la preparation du facteur viii humain et d'analogues du facteur viii.
US5661008A (en) 1991-03-15 1997-08-26 Kabi Pharmacia Ab Recombinant human factor VIII derivatives
US5770197A (en) 1991-06-27 1998-06-23 Bristol-Myers Squibb Company Methods for regulating the immune response using B7 binding molecules and IL4-binding molecules
DE69226871T3 (de) 1991-06-27 2009-09-24 Bristol-Myers Squibb Co. CTL4A-Rezeptor, ihn enthaltenden Fusionsproteine und deren Verwendung
WO1993009804A1 (en) 1991-11-18 1993-05-27 The Scripps Research Institute Serine protease derived-polypeptides and anti-peptide antibodies, systems and therapeutic methods for inhibiting coagulation
US5663060A (en) 1992-04-07 1997-09-02 Emory University Hybrid human/animal factor VIII
US5364771A (en) 1992-04-07 1994-11-15 Emory University Hybrid human/porcine factor VIII
US5744446A (en) 1992-04-07 1998-04-28 Emory University Hybrid human/animal factor VIII
US5621039A (en) 1993-06-08 1997-04-15 Hallahan; Terrence W. Factor IX- polymeric conjugates
WO1996005860A1 (en) * 1994-08-19 1996-02-29 Novo Nordisk A/S A method of treating a patient with a biologically active compound
JPH10507758A (ja) * 1994-10-19 1998-07-28 ジェネティック セラピー,インコーポレイテッド アデノウイルスおよび免疫抑制剤同時反復投与を伴う遺伝子治療
US5714583A (en) 1995-06-07 1998-02-03 Genetics Institute, Inc. Factor IX purification methods
AU710998B2 (en) * 1996-03-20 1999-10-07 Bristol-Myers Squibb Company Methods for inhibiting an immune response by blocking the GP39/CD40 and CTLA4 /CD28/B7 pathways and compositions for use therewith
DE69837322T2 (de) * 1997-01-10 2007-11-22 Biogen Idec Ma Inc., Cambridge Verfahren zur therapeutischen verabreichung von anti-cd40l-mitteln
EP1034001B1 (en) * 1997-06-20 2004-08-04 Biogen Idec MA Inc. Cd154 blockade therapy for therapeutic protein inhibitor syndrome
US8112896B2 (en) 2009-11-06 2012-02-14 Hexagon Metrology Ab Articulated arm

Also Published As

Publication number Publication date
LT4920B (lt) 2002-06-25
BR9913991A (pt) 2001-07-03
IL142069A0 (en) 2002-03-10
HUP0103960A2 (hu) 2002-02-28
WO2000016801A9 (en) 2000-10-26
AU6057899A (en) 2000-04-10
WO2000016801A1 (en) 2000-03-30
LT2001045A (en) 2002-01-25
MXPA01002898A (es) 2002-06-04
CA2343916A1 (en) 2000-03-30
HUP0103960A3 (en) 2003-09-29
EA200100385A1 (ru) 2001-10-22
HK1039059A1 (zh) 2002-04-12
LV12768A (en) 2001-12-20
KR20010085830A (ko) 2001-09-07
LV12768B (lv) 2002-06-20
CZ20011021A3 (cs) 2001-10-17
JP2002526455A (ja) 2002-08-20
SI20626A (sl) 2002-02-28
PL346796A1 (en) 2002-02-25
EA005236B1 (ru) 2004-12-30
NO20011412D0 (no) 2001-03-20
CN1331602A (zh) 2002-01-16
ZA200103156B (en) 2002-07-18
AU761206B2 (en) 2003-05-29
EP1115423A1 (en) 2001-07-18
NO20011412L (no) 2001-05-16

Similar Documents

Publication Publication Date Title
DK0643726T3 (da) Peptider af humant p53-protein til anvendelse i sammensætninger, som inducerer humant T-celle-respons, og humane p53-protei
EA200000445A1 (ru) Способы лечения состояния гиперкоагуляции или приобретенной недостаточности белка c
FI953442A0 (fi) Gonadotropiinia sisältäviä pakastekuivattuja pallosia
ATE517922T1 (de) Stabilisierte einzel-domänen-antikörper in einer pharmazeutischen zusammensetzung ausgestaltet für inhalation
FI961621A0 (fi) Proteiini:farnesyylitranseraasin substituoidut tetra- ja pentapeptidi-inhibiittorit
CY1111863T1 (el) Αντισωματα εναντιον υποδοχεα θανατου 4 (dr4) και χρησεις αυτων
WO1998022136A3 (de) Stabile lyophilisierte pharmazeutische zubereitungen von mono- oder polyklonalen antikörpern
UA95438C2 (ru) Биспецифические антитела, которые замещают функциональные белки
IL160641A0 (en) Carbohydrate binding domain containing fusion proteins for delivery of therapeutic and other agents, and compositions containing them
IL127558A0 (en) Hepatocyte growth factor receptor agonists and uses thereof
TR199901174T2 (xx) Yeni heterosiklilmetil-ikameli pirazol t�revleri.
CA2413190A1 (en) Methods for treating rheumatic diseases using a soluble ctla4 molecule
DK0836485T3 (da) Kaskade-polymer-komplekser, fremgangsmåde til deres fremstilling og farmaceutiske midler indeholdende disse
DK0915974T3 (da) Modificerede tie-2 receptor-ligander
CY1109868T1 (el) Cd81 πρωτεϊνη υποδοχεας ηπατιτιδας c
WO2001068708A3 (en) Human and humanized fap-alpha-specific antibodies
AU6832398A (en) Multiple antigen glycopeptide carbohydrate, vaccine comprising the same and use thereof
DE69434384D1 (de) Metalkomplexbildner
ATE234111T1 (de) Therapeutische verwendungen von bpi-protein produkten bei menschen mit durch trauma verursachter blutung
DK0845998T3 (da) Lægemidler til immunbehandling indeholdende antistoffer, der specifikt genkender MHCII-antigenet hos en patient, der skal behandles
WO1997029199A3 (en) Prostate specific antigen peptides and uses thereof
EP1064005A4 (en) USE OF THE UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR AS A TARGET IN THE DIAGNOSIS OF METASTASES
MX9101958A (es) Inhibidores de acat de urea de aminosulfonilo
NZ511034A (en) Methods of downmodulating the immune response to therapeutic proteins
WO2002046767A3 (en) Diagnosis and treatment of alzheimer's disease

Legal Events

Date Code Title Description
ASS Change of ownership

Owner name: AMERICAN RED CROSS, US

Free format text: OLD OWNER(S): AMERICAN RED CROSS; GENETICS INSTITUTE, INC.

Owner name: GENETICS INSTITUTE, US

Free format text: OLD OWNER(S): AMERICAN RED CROSS; GENETICS INSTITUTE, INC.

PSEA Patent sealed
RENW Renewal (renewal fees accepted)