JP2002525266A5 - - Google Patents
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- Publication number
- JP2002525266A5 JP2002525266A5 JP2000569816A JP2000569816A JP2002525266A5 JP 2002525266 A5 JP2002525266 A5 JP 2002525266A5 JP 2000569816 A JP2000569816 A JP 2000569816A JP 2000569816 A JP2000569816 A JP 2000569816A JP 2002525266 A5 JP2002525266 A5 JP 2002525266A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- antimicrobial
- combination
- drug
- gastric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000004599 antimicrobial Substances 0.000 description 6
- 229940126409 proton pump inhibitor Drugs 0.000 description 6
- 239000000612 proton pump inhibitor Substances 0.000 description 6
- 239000003814 drug Substances 0.000 description 5
- 230000002496 gastric effect Effects 0.000 description 5
- AJKIRUJIDFJUKJ-UHFFFAOYSA-N taurolidine Chemical compound C1NS(=O)(=O)CCN1CN1CNS(=O)(=O)CC1 AJKIRUJIDFJUKJ-UHFFFAOYSA-N 0.000 description 5
- 229960004267 taurolidine Drugs 0.000 description 5
- 229940124350 antibacterial drug Drugs 0.000 description 4
- 239000008194 pharmaceutical composition Substances 0.000 description 4
- 229960004157 rabeprazole Drugs 0.000 description 4
- YREYEVIYCVEVJK-UHFFFAOYSA-N rabeprazole Chemical compound COCCCOC1=CC=NC(CS(=O)C=2NC3=CC=CC=C3N=2)=C1C YREYEVIYCVEVJK-UHFFFAOYSA-N 0.000 description 4
- RJGYJMFQWGPBGM-UHFFFAOYSA-N 1,2,4-thiadiazinane 1,1-dioxide Chemical compound O=S1(=O)CCNCN1 RJGYJMFQWGPBGM-UHFFFAOYSA-N 0.000 description 3
- 230000000845 anti-microbial effect Effects 0.000 description 3
- 229950007343 taurultam Drugs 0.000 description 3
- SUBDBMMJDZJVOS-UHFFFAOYSA-N 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical class [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- 206010053155 Epigastric discomfort Diseases 0.000 description 2
- 229940069428 antacid Drugs 0.000 description 2
- 239000003159 antacid agent Substances 0.000 description 2
- 230000001458 anti-acid effect Effects 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 210000001156 gastric mucosa Anatomy 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000002458 infectious effect Effects 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 229960000381 omeprazole Drugs 0.000 description 2
- 239000011253 protective coating Substances 0.000 description 2
- 208000007882 Gastritis Diseases 0.000 description 1
- 206010061459 Gastrointestinal ulcer Diseases 0.000 description 1
- 241000589989 Helicobacter Species 0.000 description 1
- 241000590002 Helicobacter pylori Species 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 210000004211 gastric acid Anatomy 0.000 description 1
- 229940037467 helicobacter pylori Drugs 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15445198A | 1998-09-16 | 1998-09-16 | |
| US09/154,451 | 1999-05-20 | ||
| US09/316,115 | 1999-05-20 | ||
| US09/316,115 US6117868A (en) | 1998-09-16 | 1999-05-20 | Treatment of gastrointestinal ulcers or gastritis caused by microbial infection |
| PCT/GB1999/003030 WO2000015232A1 (en) | 1998-09-16 | 1999-09-13 | Taurolidine and/or taurultam against infectious ulcer or gastritis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002525266A JP2002525266A (ja) | 2002-08-13 |
| JP2002525266A5 true JP2002525266A5 (enExample) | 2006-11-02 |
| JP4981208B2 JP4981208B2 (ja) | 2012-07-18 |
Family
ID=26851461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000569816A Expired - Fee Related JP4981208B2 (ja) | 1998-09-16 | 1999-09-13 | 感染性潰瘍又は胃炎に対するタウロリジン及び／又はタウルルタム |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6117868A (enExample) |
| EP (1) | EP1112074B1 (enExample) |
| JP (1) | JP4981208B2 (enExample) |
| CA (1) | CA2344308C (enExample) |
| DE (1) | DE69916629T2 (enExample) |
| ES (1) | ES2219061T3 (enExample) |
| RU (1) | RU2227033C2 (enExample) |
| WO (1) | WO2000015232A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050124608A1 (en) * | 2001-04-03 | 2005-06-09 | Redmond H. P. | Treatment of cancers |
| US8304390B2 (en) * | 1997-07-31 | 2012-11-06 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of treatment for preventing or reducing tumor growth in the liver of patient |
| US7345039B2 (en) * | 1999-06-04 | 2008-03-18 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer |
| US7892530B2 (en) * | 1999-06-04 | 2011-02-22 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of tumor metastases and cancer |
| US8030301B2 (en) * | 1999-06-04 | 2011-10-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of cancers with methylol-containing compounds and at least one electrolyte |
| JP2001122777A (ja) * | 1999-10-27 | 2001-05-08 | Nagase & Co Ltd | 抗潰瘍剤 |
| CA2393252A1 (en) | 1999-12-06 | 2001-06-07 | Paul Calabresi | Use of methylol-containing compounds to treat tumors |
| CN100519525C (zh) * | 1999-12-06 | 2009-07-29 | 葛兰素集团有限公司 | 芳香砜类及其医疗用途 |
| FR2803206A1 (fr) * | 1999-12-30 | 2001-07-06 | Aventis Pharma Sa | Composition comprenant des acides nucleiques, preparation et utilisation |
| US6365198B1 (en) * | 2001-01-28 | 2002-04-02 | Gulf Pharmaceutical Industries | Pharmaceutical preparation for the treatment of gastrointestinal ulcers and hemorrhoids |
| WO2003028642A2 (en) | 2001-10-01 | 2003-04-10 | Rhode Island Hospital, A Lifespan Partner | Methods of inhibiting metastases |
| FI20021819A0 (fi) * | 2002-10-14 | 2002-10-14 | Pekka Untamo Heino | Valmiste alkoholin metabolian tehostamiseksi |
| RU2265437C2 (ru) * | 2003-07-02 | 2005-12-10 | Суханов Александр Владимирович | Способ лечения заболеваний желудка и двенадцатиперстной кишки, вызванных helicobacter pylori |
| JP2007537200A (ja) * | 2004-05-14 | 2007-12-20 | ハンス−ディートリヒ・ポラシェグ | タウロリジン製剤及び投与：細菌マイクロフィルム形成に対する治療処置及び抗菌保護 |
| PL1967195T3 (pl) * | 2006-12-20 | 2012-03-30 | Kyowa Chem Ind Co Ltd | Środek zobojętniający kwas |
| RU2410100C2 (ru) | 2009-03-30 | 2011-01-27 | Александр Владимирович Диковский | Фармацевтическая композиция ингибитора протонной помпы и пребиотика для лечения язвенных поражений желудка и 12-перстной кишки |
| AR080292A1 (es) * | 2010-02-24 | 2012-03-28 | Emisphere Tech Inc | Metodo para normalizar en forma rapida los niveles de vitamina b12 en un paciente que tiene deficiencia de vitamina b12 y un nivel promedio de vitamina b12 por debajo de 350 pg/ml |
| EP2601947A1 (en) * | 2011-12-05 | 2013-06-12 | Abo Bakr Mohammed Ali Al-Mehdar | Fixed-dose combination for treatment of helicobacter pylori associated diseases |
| US9241943B2 (en) | 2012-06-18 | 2016-01-26 | Geistlich Pharma Ag | Oxathiazine derivatives as antibacterial and anticancer agents |
| US20170100407A1 (en) * | 2015-10-07 | 2017-04-13 | Cormedix Inc. | Skin-penetrating formulation of taurolidine |
| CN117159461A (zh) * | 2023-07-26 | 2023-12-05 | 合肥远志医药科技开发有限公司 | 一种铝碳酸镁混悬液及其制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1124285A (en) * | 1964-10-06 | 1968-08-21 | Geistlich Soehne Ag | Novel perhydro-1,2,4-thiadiazine dioxides-(1,1), their preparation and compositionscontaining them |
| US5256684A (en) * | 1985-06-13 | 1993-10-26 | The Procter & Gamble Company | Methods and compositions for the treatment of gastrointestinal disorders |
| DE3533612A1 (de) * | 1985-09-20 | 1987-04-02 | Johannes Reinmueller | Neuartige verwendung von taurolin |
| GB8617482D0 (en) * | 1986-07-17 | 1986-08-28 | Geistlich Soehne Ag | Pharmaceutical composition |
| US5210083A (en) * | 1986-07-17 | 1993-05-11 | Ed. Geistlich Sohne A.G. Fur Chemische Industrie | Pharmaceutical compositions |
| EP0406248B1 (de) * | 1989-01-19 | 1994-06-08 | Alfred Schmidt | Verwendung von dimethylpolysiloxan zur behandlung von erkrankungen des gastrointestinaltraktes |
| GB9005856D0 (en) * | 1990-03-15 | 1990-05-09 | Geistlich Soehne Ag | Compositions |
| TW276996B (enExample) * | 1992-04-24 | 1996-06-01 | Astra Ab | |
| SE9500422D0 (sv) * | 1995-02-06 | 1995-02-06 | Astra Ab | New oral pharmaceutical dosage forms |
| JPH09121890A (ja) * | 1995-10-30 | 1997-05-13 | Mitsubishi Kagaku B C L:Kk | ヘリコバクター属細菌の検出方法 |
| SE507682C2 (sv) * | 1996-03-29 | 1998-07-06 | Marcin Krotkiewski | Farmaceutisk beredning för behandling av gastrit, refluxesofagit, duodenit, dyspepsi och magsårssjukdom innehållande en blandning av ammoniumvismutcitrat och ett alginat |
| JPH1017471A (ja) * | 1996-07-04 | 1998-01-20 | Yoshitomi Pharmaceut Ind Ltd | ピリジン化合物系併用医薬 |
| JP3677376B2 (ja) * | 1996-08-13 | 2005-07-27 | 武田薬品工業株式会社 | 医薬 |
| US5972933A (en) * | 1998-01-08 | 1999-10-26 | Ed. Geistlich Sohne Ag Fur Chemische Industrie | Method of treating microbial infections |
-
1999
- 1999-05-20 US US09/316,115 patent/US6117868A/en not_active Expired - Lifetime
- 1999-09-13 RU RU2001107149/15A patent/RU2227033C2/ru not_active IP Right Cessation
- 1999-09-13 CA CA002344308A patent/CA2344308C/en not_active Expired - Fee Related
- 1999-09-13 DE DE69916629T patent/DE69916629T2/de not_active Expired - Lifetime
- 1999-09-13 ES ES99946325T patent/ES2219061T3/es not_active Expired - Lifetime
- 1999-09-13 WO PCT/GB1999/003030 patent/WO2000015232A1/en not_active Ceased
- 1999-09-13 EP EP99946325A patent/EP1112074B1/en not_active Expired - Lifetime
- 1999-09-13 JP JP2000569816A patent/JP4981208B2/ja not_active Expired - Fee Related
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