JP2002520286A - Ｇａｂａ類縁体及びカフェインを含んでなる組成物 - Google Patents
Ｇａｂａ類縁体及びカフェインを含んでなる組成物Info
- Publication number
- JP2002520286A JP2002520286A JP2000558822A JP2000558822A JP2002520286A JP 2002520286 A JP2002520286 A JP 2002520286A JP 2000558822 A JP2000558822 A JP 2000558822A JP 2000558822 A JP2000558822 A JP 2000558822A JP 2002520286 A JP2002520286 A JP 2002520286A
- Authority
- JP
- Japan
- Prior art keywords
- caffeine
- composition
- formula
- compound
- gabapentin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- JWBPVFVNISJVEM-UHFFFAOYSA-M sodium caffeine benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1.CN1C(=O)N(C)C(=O)C2=C1N=CN2C JWBPVFVNISJVEM-UHFFFAOYSA-M 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 239000008247 solid mixture Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 206010042772 syncope Diseases 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 238000010189 synthetic method Methods 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 229940095374 tabloid Drugs 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 206010044652 trigeminal neuralgia Diseases 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9213198P | 1998-07-09 | 1998-07-09 | |
| US60/092,131 | 1998-07-09 | ||
| PCT/US1999/013670 WO2000002562A1 (en) | 1998-07-09 | 1999-06-18 | Compositions comprising gaba analogs and caffeine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002520286A true JP2002520286A (ja) | 2002-07-09 |
| JP2002520286A5 JP2002520286A5 (enExample) | 2006-08-10 |
Family
ID=22231777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000558822A Withdrawn JP2002520286A (ja) | 1998-07-09 | 1999-06-18 | Ｇａｂａ類縁体及びカフェインを含んでなる組成物 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6326374B1 (enExample) |
| EP (1) | EP1094817A1 (enExample) |
| JP (1) | JP2002520286A (enExample) |
| KR (1) | KR20010071777A (enExample) |
| AU (1) | AU772156B2 (enExample) |
| BR (1) | BR9911917A (enExample) |
| CA (1) | CA2332915C (enExample) |
| ID (1) | ID28277A (enExample) |
| NO (1) | NO20010119D0 (enExample) |
| NZ (1) | NZ508490A (enExample) |
| PL (1) | PL345340A1 (enExample) |
| WO (1) | WO2000002562A1 (enExample) |
| ZA (1) | ZA200007168B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6001876A (en) | 1996-07-24 | 1999-12-14 | Warner-Lambert Company | Isobutylgaba and its derivatives for the treatment of pain |
| US6992109B1 (en) * | 1999-04-08 | 2006-01-31 | Segal Catherine A | Method for the treatment of incontinence |
| WO2000061188A1 (en) * | 1999-04-09 | 2000-10-19 | Euro-Celtique S.A. | Sodium channel blocker compositions and the use thereof |
| US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| ATE317280T1 (de) | 2001-09-03 | 2006-02-15 | Newron Pharm Spa | Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung |
| RU2335342C2 (ru) * | 2004-03-12 | 2008-10-10 | Уорнер-Ламберт Компани Ллс | C1-симметричные бисфосфиновые лиганды и их применение в асимметрическом синтезе прегабалина |
| JP2007530657A (ja) * | 2004-04-01 | 2007-11-01 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | Ｐキラル性ホスホランの調製および不斉合成でのその使用 |
| EA200800909A1 (ru) | 2004-06-21 | 2008-08-29 | УОРНЕР-ЛАМБЕРТ КОМПАНИ ЭлЭлСи | Получение прегабалина и родственных соединений |
| SI1809271T1 (sl) * | 2004-09-10 | 2010-10-29 | Newron Pharm Spa | Uporaba (R)-(halobenziloksi) benzilamino propanamidov kot selektivnih modulatorjev natrijevih in/ali kalcijevih kanalov |
| EP1963280B1 (en) | 2005-12-22 | 2015-10-28 | Newron Pharmaceuticals S.p.A. | 2-phenylethylamino derivatives as calcium and/or sodium channel modulators |
| US7645767B2 (en) * | 2006-08-31 | 2010-01-12 | Trinity Laboratories, Inc. | Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy |
| CH699327B1 (de) | 2007-02-14 | 2010-03-15 | Oerlikon Heberlein Temco Wattw | Vorrichtung zum gleichzeitigen Behandeln von mehreren multifilen Fäden. |
| JP5592790B2 (ja) | 2007-08-06 | 2014-09-17 | トリニティ ラボラトリーズ インコーポレイテッド | 慢性疼痛およびニューロパシーに関連する疼痛を治療する医薬組成物 |
| SG157299A1 (en) * | 2008-05-09 | 2009-12-29 | Agency Science Tech & Res | Diagnosis and treatment of kawasaki disease |
| US20100190752A1 (en) | 2008-09-05 | 2010-07-29 | Gruenenthal Gmbh | Pharmaceutical Combination |
| WO2011141923A2 (en) | 2010-05-14 | 2011-11-17 | Lupin Limited | Improved synthesis of optically pure (s) - 3-cyano-5-methyl-hexanoic acid alkyl ester, an intermediate of (s)- pregabalin |
| WO2012059797A1 (en) | 2010-11-04 | 2012-05-10 | Lupin Limited | Process for synthesis of (s) - pregabalin |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4656177A (en) | 1982-07-22 | 1987-04-07 | Analgesic Associates | Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same |
| US5248678A (en) * | 1992-06-30 | 1993-09-28 | Fractal Laboratories, Inc. | Methods for increasing arousal and alertness and for the amelioration of comatose states |
| CA2170485C (en) * | 1993-09-07 | 2000-11-07 | Sekhar Mitra | Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agents and caffeine |
| US5443838A (en) | 1993-09-15 | 1995-08-22 | Koenig, Jr.; Steven M. | Nutritional supplementation system |
| PL185991B1 (pl) * | 1996-03-14 | 2003-09-30 | Warner Lambert Co | Nowe podstawione cykliczne aminokwasy i kompozycja farmaceutyczna |
| DE69733081T2 (de) * | 1996-08-23 | 2006-05-11 | Endo Pharmaceuticals Inc. (n.d.Ges.d. Staates Delaware) | Antikonvulsive mitteln enthaltende zubereitung zur behandlung von neuropathischen schmerzen |
| AU733896B2 (en) * | 1996-10-23 | 2001-05-31 | Warner-Lambert Company | Substituted gamma aminobutyric acids as pharmaceutical agents |
| WO1999012537A1 (en) * | 1997-09-08 | 1999-03-18 | Warner-Lambert Company | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
-
1999
- 1999-06-18 ID IDW20010054A patent/ID28277A/id unknown
- 1999-06-18 WO PCT/US1999/013670 patent/WO2000002562A1/en not_active Ceased
- 1999-06-18 CA CA002332915A patent/CA2332915C/en not_active Expired - Fee Related
- 1999-06-18 KR KR1020017000260A patent/KR20010071777A/ko not_active Ceased
- 1999-06-18 JP JP2000558822A patent/JP2002520286A/ja not_active Withdrawn
- 1999-06-18 NZ NZ508490A patent/NZ508490A/en unknown
- 1999-06-18 EP EP99930357A patent/EP1094817A1/en not_active Ceased
- 1999-06-18 AU AU46910/99A patent/AU772156B2/en not_active Ceased
- 1999-06-18 PL PL99345340A patent/PL345340A1/xx not_active Application Discontinuation
- 1999-06-18 BR BR9911917-0A patent/BR9911917A/pt not_active Application Discontinuation
- 1999-06-18 US US09/743,371 patent/US6326374B1/en not_active Expired - Fee Related
-
2000
- 2000-12-04 ZA ZA200007168A patent/ZA200007168B/en unknown
-
2001
- 2001-01-08 NO NO20010119A patent/NO20010119D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR9911917A (pt) | 2001-03-27 |
| PL345340A1 (en) | 2001-12-17 |
| NZ508490A (en) | 2003-08-29 |
| CA2332915C (en) | 2006-10-24 |
| CA2332915A1 (en) | 2000-01-20 |
| US6326374B1 (en) | 2001-12-04 |
| NO20010119L (no) | 2001-01-08 |
| KR20010071777A (ko) | 2001-07-31 |
| ZA200007168B (en) | 2002-03-04 |
| AU4691099A (en) | 2000-02-01 |
| WO2000002562A1 (en) | 2000-01-20 |
| ID28277A (id) | 2001-05-10 |
| EP1094817A1 (en) | 2001-05-02 |
| AU772156B2 (en) | 2004-04-08 |
| NO20010119D0 (no) | 2001-01-08 |
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Legal Events
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| A521 | Request for written amendment filed |
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