JP2002520008A5 - - Google Patents

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Publication number
JP2002520008A5
JP2002520008A5 JP2000559128A JP2000559128A JP2002520008A5 JP 2002520008 A5 JP2002520008 A5 JP 2002520008A5 JP 2000559128 A JP2000559128 A JP 2000559128A JP 2000559128 A JP2000559128 A JP 2000559128A JP 2002520008 A5 JP2002520008 A5 JP 2002520008A5
Authority
JP
Japan
Prior art keywords
pna
library
oligomer
nucleotide
base
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000559128A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002520008A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1999/014969 external-priority patent/WO2000002899A1/en
Publication of JP2002520008A publication Critical patent/JP2002520008A/ja
Publication of JP2002520008A5 publication Critical patent/JP2002520008A5/ja
Pending legal-status Critical Current

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JP2000559128A 1998-07-09 1999-07-01 Ｄｎａ配列ハイブリッド形成を最適化するための改良されたペプチド核酸汎用ライブラリーの使用法 Pending JP2002520008A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11321198A 1998-07-09 1998-07-09
US09/113,211 1998-07-09
PCT/US1999/014969 WO2000002899A1 (en) 1998-07-09 1999-07-01 Method of using an improved peptide nucleic acid universal library to optimize dna sequence hybridation

Publications (2)

Publication Number Publication Date
JP2002520008A JP2002520008A (ja) 2002-07-09
JP2002520008A5 true JP2002520008A5 (enExample) 2006-08-17

Family

ID=22348188

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000559128A Pending JP2002520008A (ja) 1998-07-09 1999-07-01 Ｄｎａ配列ハイブリッド形成を最適化するための改良されたペプチド核酸汎用ライブラリーの使用法

Country Status (8)

Country Link
US (1) US6433134B1 (enExample)
EP (1) EP1095054B1 (enExample)
JP (1) JP2002520008A (enExample)
KR (1) KR100694914B1 (enExample)
AT (1) ATE343586T1 (enExample)
AU (1) AU4965499A (enExample)
DE (1) DE69933770D1 (enExample)
WO (1) WO2000002899A1 (enExample)

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ATE346950T1 (de) 2001-03-09 2006-12-15 Boston Probes Inc Kombinationsoligomere betreffende verfahren, kits und zusammensetzungen
ATE365792T1 (de) * 2001-04-03 2007-07-15 Biocept Inc Verfahren und gelzusammensetzungen zum einkapseln lebender zellen und organischer moleküle
EP1421216A4 (en) 2001-09-01 2006-05-17 Samsung Electronics Co Ltd PROCESS FOR PRODUCING A HYDROGEL BIOPUCE USING AN ETOILE POLYETHYLENE GLYCOL DERIVATIVE COMPRISING AN EPOXY GROUP
WO2003040395A2 (en) * 2001-11-07 2003-05-15 Applera Corporation Universal nucleotides for nucleic acid analysis
AU2002351164A1 (en) * 2001-11-26 2003-06-10 Molecular Reflections, Inc. Microscale immobilization of molecules using a hydrogel and methods of use thereof
KR100464261B1 (ko) 2002-01-24 2005-01-03 주식회사 파나진 Ｐｎａ 올리고머를 합성하기 위한 신규한 단량체 및 그의제조방법
US20030175828A1 (en) * 2002-03-15 2003-09-18 Lazar James G. Signal amplification by Hybrid Capture
KR20030084444A (ko) 2002-04-26 2003-11-01 주식회사 파나진 Ｐｎａ 올리고머를 합성하기 위한 신규한 단량체 및 그의제조방법
ATE449103T1 (de) * 2002-09-08 2009-12-15 Applera Corp Festphasengebundene pna-dimere und deren synthese
WO2004111072A2 (en) * 2003-06-12 2004-12-23 Applera Corporation Combinatorial nucleobase oligomers comprising universal base analogues and methods for making and using same
US7211668B2 (en) * 2003-07-28 2007-05-01 Panagene, Inc. PNA monomer and precursor
WO2006076650A2 (en) * 2005-01-12 2006-07-20 Applera Corporation Compositions, methods, and kits for selective amplification of nucleic acids
US7482353B2 (en) 2005-06-15 2009-01-27 Applied Biosystems Inc. Compositions and methods pertaining to PNA synthons and oligomers comprising a universal base
EP1943348B1 (en) 2005-10-03 2013-01-02 Life Technologies Corporation Compositions, methods, and kits for amplifying nucleic acids
US20070172842A1 (en) * 2006-01-25 2007-07-26 Andreas Braun Methods for isolating and identifying novel target-specific structuremers for use in the biological sciences
US9174216B2 (en) 2013-03-13 2015-11-03 DeNovo Science, Inc. System for capturing and analyzing cells
CA2842359A1 (en) 2011-08-01 2013-02-07 Denovo Sciences Cell capture system and method of use
US10466160B2 (en) 2011-08-01 2019-11-05 Celsee Diagnostics, Inc. System and method for retrieving and analyzing particles
US9404864B2 (en) 2013-03-13 2016-08-02 Denovo Sciences, Inc. System for imaging captured cells
US9606102B2 (en) 2013-01-26 2017-03-28 Denovo Sciences, Inc. System and method for capturing and analyzing cells
US9707562B2 (en) 2013-03-13 2017-07-18 Denovo Sciences, Inc. System for capturing and analyzing cells
US9856535B2 (en) 2013-05-31 2018-01-02 Denovo Sciences, Inc. System for isolating cells
US10391490B2 (en) 2013-05-31 2019-08-27 Celsee Diagnostics, Inc. System and method for isolating and analyzing cells
US10159652B2 (en) 2013-10-16 2018-12-25 The University Of British Columbia Device for formulating particles at small volumes
WO2016138175A1 (en) 2015-02-24 2016-09-01 The University Of British Columbia Continuous flow microfluidic system
WO2017117647A1 (en) 2016-01-06 2017-07-13 The University Of British Columbia Bifurcating mixers and methods of their use and manufacture
CN106117153B (zh) * 2016-07-05 2018-11-23 淮阴师范学院 2-哌嗪酮的制备方法
EP3609897A1 (en) * 2017-04-12 2020-02-19 H. Hoffnabb-La Roche Ag A method for labeling of aldehyde containing target molecules
CN111295245B (zh) 2017-08-29 2021-03-16 伯乐实验室有限公司 用于分离和分析细胞的系统和方法
WO2019089567A1 (en) 2017-10-30 2019-05-09 Massachusetts Institute Of Technology Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
US10633693B1 (en) 2019-04-16 2020-04-28 Celsee Diagnostics, Inc. System and method for leakage control in a particle capture system
US11273439B2 (en) 2019-05-07 2022-03-15 Bio-Rad Laboratories, Inc. System and method for target material retrieval from microwells
JP7413408B2 (ja) 2019-05-07 2024-01-15 バイオ－ラッド ラボラトリーズ インコーポレイテッド 自動化された単一細胞処理のためのシステムおよび方法
EP3975841A1 (en) 2019-05-30 2022-04-06 Massachusetts Institute of Technology Peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids
CN118291246A (zh) 2019-06-14 2024-07-05 伯乐实验室有限公司 用于自动化单细胞处理和分析的系统和方法
CN110511973B (zh) * 2019-07-16 2021-05-07 杭州原合生物科技有限公司 一种用于核酸原位合成的固相载体及其制备方法
KR102403904B1 (ko) * 2019-12-24 2022-06-02 주식회사 시선바이오머티리얼스 용액공정상 pna 올리고머의 제조방법
US11504719B2 (en) 2020-03-12 2022-11-22 Bio-Rad Laboratories, Inc. System and method for receiving and delivering a fluid for sample processing
KR102978222B1 (ko) 2020-10-29 2026-06-16 엘지전자 주식회사 청소기
WO2023107539A1 (en) 2021-12-10 2023-06-15 Bio-Rad Laboratories, Inc. Compositions, methods, and systems for sample processing with morphology-adjustable functionalized particles
KR102804687B1 (ko) 2023-02-10 2025-05-12 엘지전자 주식회사 청소기 및 청소기 제어 방법

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JP2528107B2 (ja) 1985-03-15 1996-08-28 サマ−トン，ジエ−ムス ポリヌクレオチド測定試薬と方法
US5539082A (en) 1993-04-26 1996-07-23 Nielsen; Peter E. Peptide nucleic acids
DK51092D0 (da) 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
US5641625A (en) 1992-05-22 1997-06-24 Isis Pharmaceuticals, Inc. Cleaving double-stranded DNA with peptide nucleic acids
US5714331A (en) 1991-05-24 1998-02-03 Buchardt, Deceased; Ole Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
US5766855A (en) 1991-05-24 1998-06-16 Buchardt, Deceased; Ole Peptide nucleic acids having enhanced binding affinity and sequence specificity
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US5438131A (en) 1992-09-16 1995-08-01 Bergstrom; Donald E. 3-nitropyrrole nucleoside
US5539083A (en) * 1994-02-23 1996-07-23 Isis Pharmaceuticals, Inc. Peptide nucleic acid combinatorial libraries and improved methods of synthesis
US5738996A (en) 1994-06-15 1998-04-14 Pence, Inc. Combinational library composition and method
EP0804456B1 (en) 1994-10-06 2002-08-21 Isis Pharmaceuticals, Inc. Peptide nucleic acid conjugates
EP0792283A1 (en) 1994-11-14 1997-09-03 Chiron Corporation SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH
WO1996020212A2 (en) * 1994-12-28 1996-07-04 Buchardt, Dorte Peptide nucleic acid incorporating a chiral backbone
DE19532553A1 (de) 1995-09-04 1997-03-06 Hoechst Ag Verfahren zur Herstellung substituierter N-Ethyl-Glycinderivate
DE19627898A1 (de) 1996-07-11 1998-01-15 Hoechst Ag Festphasensynthese von Oligonucleotiden

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