JP2002518993A - アミノ酸欠失および置換を有するセリンプロテアーゼ変異体 - Google Patents

アミノ酸欠失および置換を有するセリンプロテアーゼ変異体

Info

Publication number
JP2002518993A
JP2002518993A JP2000538017A JP2000538017A JP2002518993A JP 2002518993 A JP2002518993 A JP 2002518993A JP 2000538017 A JP2000538017 A JP 2000538017A JP 2000538017 A JP2000538017 A JP 2000538017A JP 2002518993 A JP2002518993 A JP 2002518993A
Authority
JP
Japan
Prior art keywords
variants
amino acid
present
acid sequence
variant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2000538017A
Other languages
English (en)
Japanese (ja)
Inventor
ドン、ネルトン、ルービン
エリザベス、エレン、シコルスキー
ポール、エリオット、コレア
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Publication of JP2002518993A publication Critical patent/JP2002518993A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208—Tissues; Wipes; Patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/86—Products or compounds obtained by genetic engineering
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2000538017A 1998-03-26 1999-03-25 アミノ酸欠失および置換を有するセリンプロテアーゼ変異体 Withdrawn JP2002518993A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7947798P 1998-03-26 1998-03-26
US60/079,477 1998-03-26
PCT/IB1999/000520 WO1999049057A1 (fr) 1998-03-26 1999-03-25 Variants de serine-proteases ayant des deletions et des substitutions d'acides amines

Publications (1)

Publication Number Publication Date
JP2002518993A true JP2002518993A (ja) 2002-07-02

Family

ID=22150818

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000538017A Withdrawn JP2002518993A (ja) 1998-03-26 1999-03-25 アミノ酸欠失および置換を有するセリンプロテアーゼ変異体

Country Status (9)

Country Link
EP (1) EP1082443A1 (fr)
JP (1) JP2002518993A (fr)
KR (1) KR20010052223A (fr)
CN (1) CN1303437A (fr)
AR (1) AR023021A1 (fr)
AU (1) AU750336B2 (fr)
BR (1) BR9909147A (fr)
CA (1) CA2324422A1 (fr)
WO (1) WO1999049057A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5928100A (en) * 1999-07-22 2001-02-13 Procter & Gamble Company, The Subtilisin protease variants having amino acid deletions and substitutions in defined epitope regions
US6803222B2 (en) 2000-11-22 2004-10-12 Kao Corporation Alkaline proteases
DE10360805A1 (de) 2003-12-23 2005-07-28 Henkel Kgaa Neue Alkalische Protease und Wasch- und Reinigungsmittel, enthaltend diese neue Alkalische Protease
DE102007003143A1 (de) 2007-01-16 2008-07-17 Henkel Kgaa Neue Alkalische Protease aus Bacillus gibsonii und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease
DE102007032111B4 (de) 2007-07-09 2017-07-20 Henkel Ag & Co. Kgaa Neue Proteasen und Wasch- und Reinigungsmittel enthaltend diese Proteasen
DE102007036756A1 (de) 2007-08-03 2009-02-05 Henkel Ag & Co. Kgaa Neue Proteasen und Wasch- und Reinigungsmittel, enthaltend diese neuen Proteasen
DE102007051092A1 (de) 2007-10-24 2009-04-30 Henkel Ag & Co. Kgaa Subtilisin aus Becillus pumilus und Wasch- und Reinigungsmittel enthaltend dieses neue Subtilisin
DK2421973T3 (en) * 2009-04-24 2018-07-30 Danisco Us Inc PROTEAS WITH MODIFIED PRO AREAS
RU2639534C2 (ru) * 2009-09-25 2017-12-21 Новозимс А/С Применение вариантов протеазы
WO2013076269A1 (fr) * 2011-11-25 2013-05-30 Novozymes A/S Variants de subtilase et polynucléotides codants pour ceux-ci
CN102839165B (zh) * 2012-09-26 2014-12-10 金普诺安生物科技（苏州）有限公司 基因突变型重组蛋白酶k及其工业化生产方法
EP4291647A1 (fr) * 2021-02-12 2023-12-20 Fresenius Kabi iPSUM S.r.l. Variants de subtilisine et leur utilisation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0916732B1 (fr) * 1987-04-06 2007-08-22 Novozymes A/S Stabilisation de protéines par mise au point des interactions électrostatiques aux sites de liaison d'ions métalliques
ES2227508T3 (es) * 1989-06-26 2005-04-01 Unilever N.V. Composiciones detergentes enzimaticas.
WO1992010755A1 (fr) * 1990-12-05 1992-06-25 Novo Nordisk A/S Proteines presentant des epitopes modifies et procedes de preparation de ces proteines
US5567601A (en) * 1993-06-01 1996-10-22 University Of Maryland Subtilisin mutants lacking a primary calcium binding site
WO1999049056A1 (fr) * 1998-03-26 1999-09-30 The Procter & Gamble Company Variants de serine-proteases ayant des substitutions d'acides amines

Also Published As

Publication number Publication date
CN1303437A (zh) 2001-07-11
CA2324422A1 (fr) 1999-09-30
BR9909147A (pt) 2000-12-05
EP1082443A1 (fr) 2001-03-14
AU750336B2 (en) 2002-07-18
AR023021A1 (es) 2002-09-04
KR20010052223A (ko) 2001-06-25
WO1999049057A1 (fr) 1999-09-30
AU2742699A (en) 1999-10-18

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Legal Events

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Effective date: 20060606