JP2002518348A5 - - Google Patents
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- Publication number
- JP2002518348A5 JP2002518348A5 JP2000554404A JP2000554404A JP2002518348A5 JP 2002518348 A5 JP2002518348 A5 JP 2002518348A5 JP 2000554404 A JP2000554404 A JP 2000554404A JP 2000554404 A JP2000554404 A JP 2000554404A JP 2002518348 A5 JP2002518348 A5 JP 2002518348A5
- Authority
- JP
- Japan
- Prior art keywords
- benzyl alcohol
- water
- concentration
- prostaglandin
- dinoprost tromethamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- WVDDGKGOMKODPV-UHFFFAOYSA-N benzyl alcohol Substances OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 description 40
- 235000019445 benzyl alcohol Nutrition 0.000 description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 11
- ABYGSZMCWVXFCQ-UHFFFAOYSA-N 4-propylheptane Chemical compound CCCC(CCC)CCC ABYGSZMCWVXFCQ-UHFFFAOYSA-N 0.000 description 7
- 229960004280 dinoprost tromethamine Drugs 0.000 description 7
- 150000003180 prostaglandins Chemical class 0.000 description 6
- 239000007864 aqueous solution Substances 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 239000007788 liquid Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000002253 acid Substances 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/094,985 US6187818B1 (en) | 1998-06-17 | 1998-06-17 | Prostaglandins formulation and process |
| US09/094,985 | 1998-06-17 | ||
| PCT/US1999/011808 WO1999065527A1 (en) | 1998-06-17 | 1999-06-08 | Solution comprising prostaglandins and benzyl alcohol |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002518348A JP2002518348A (ja) | 2002-06-25 |
| JP2002518348A5 true JP2002518348A5 (https=) | 2006-06-15 |
| JP4472175B2 JP4472175B2 (ja) | 2010-06-02 |
Family
ID=22248341
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000554404A Expired - Lifetime JP4472175B2 (ja) | 1998-06-17 | 1999-06-08 | プロスタグランジンおよびベンジルアルコールを含む液剤 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6187818B1 (https=) |
| EP (1) | EP1085907B1 (https=) |
| JP (1) | JP4472175B2 (https=) |
| KR (1) | KR100608176B1 (https=) |
| CN (1) | CN1188170C (https=) |
| AT (1) | ATE263576T1 (https=) |
| AU (1) | AU752047B2 (https=) |
| CA (1) | CA2331284C (https=) |
| DE (1) | DE69916266T2 (https=) |
| DK (1) | DK1085907T3 (https=) |
| ES (1) | ES2219036T3 (https=) |
| NZ (1) | NZ508947A (https=) |
| PT (1) | PT1085907E (https=) |
| WO (1) | WO1999065527A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE281432T1 (de) | 1999-03-05 | 2004-11-15 | Univ Duke | C-16 ungesätigte fp-selektive prostaglandin analoge |
| US6894175B1 (en) | 1999-08-04 | 2005-05-17 | The Procter & Gamble Company | 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use |
| US20020172693A1 (en) | 2000-03-31 | 2002-11-21 | Delong Michell Anthony | Compositions and methods for treating hair loss using non-naturally occurring prostaglandins |
| US20020037914A1 (en) | 2000-03-31 | 2002-03-28 | Delong Mitchell Anthony | Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins |
| US20020013294A1 (en) | 2000-03-31 | 2002-01-31 | Delong Mitchell Anthony | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives |
| CN108078998B (zh) * | 2017-11-23 | 2018-09-21 | 宁波三生生物科技有限公司 | 一种氨基丁三醇前列腺素F2α注射液及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3885041A (en) * | 1970-12-28 | 1975-05-20 | Searle & Co | Antiinflammatory use of prostaglandins |
| US3917864A (en) | 1973-02-12 | 1975-11-04 | Sultanali M M Karim | Use of prostaglandins E and F for induction of labor |
| US3903297A (en) | 1973-11-01 | 1975-09-02 | Upjohn Co | Method of treatment and prophylaxis of gastric hypersecretion and gastric and duodenal ulcers using prostaglandin analogs |
| EP0268066A3 (en) | 1986-10-17 | 1990-07-11 | Syntex (U.S.A.) Inc. | Fertility control and uterine therapy in dogs with luteinizing hormone releasing hormone antagonists |
| AR002194A1 (es) | 1997-03-17 | 1998-01-07 | Sanchez Reynaldo Alemany | Instrumento computarizado para el analisis del movimiento. |
-
1998
- 1998-06-17 US US09/094,985 patent/US6187818B1/en not_active Expired - Lifetime
-
1999
- 1999-06-08 EP EP99935286A patent/EP1085907B1/en not_active Expired - Lifetime
- 1999-06-08 CN CNB998062677A patent/CN1188170C/zh not_active Expired - Lifetime
- 1999-06-08 JP JP2000554404A patent/JP4472175B2/ja not_active Expired - Lifetime
- 1999-06-08 PT PT99935286T patent/PT1085907E/pt unknown
- 1999-06-08 NZ NZ508947A patent/NZ508947A/en not_active IP Right Cessation
- 1999-06-08 AT AT99935286T patent/ATE263576T1/de active
- 1999-06-08 DE DE69916266T patent/DE69916266T2/de not_active Expired - Lifetime
- 1999-06-08 ES ES99935286T patent/ES2219036T3/es not_active Expired - Lifetime
- 1999-06-08 KR KR1020007014321A patent/KR100608176B1/ko not_active Expired - Lifetime
- 1999-06-08 WO PCT/US1999/011808 patent/WO1999065527A1/en not_active Ceased
- 1999-06-08 DK DK99935286T patent/DK1085907T3/da active
- 1999-06-08 CA CA002331284A patent/CA2331284C/en not_active Expired - Lifetime
- 1999-06-08 AU AU50796/99A patent/AU752047B2/en not_active Expired
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