JP2002516568A5 - - Google Patents

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Publication number
JP2002516568A5
JP2002516568A5 JP1998538676A JP53867698A JP2002516568A5 JP 2002516568 A5 JP2002516568 A5 JP 2002516568A5 JP 1998538676 A JP1998538676 A JP 1998538676A JP 53867698 A JP53867698 A JP 53867698A JP 2002516568 A5 JP2002516568 A5 JP 2002516568A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998538676A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002516568A (ja
Filing date
Publication date
Priority claimed from US09/033,428 external-priority patent/US6254862B1/en
Application filed filed Critical
Publication of JP2002516568A publication Critical patent/JP2002516568A/ja
Publication of JP2002516568A5 publication Critical patent/JP2002516568A5/ja
Ceased legal-status Critical Current

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JP53867698A 1997-03-03 1998-03-03 α−フェトタンパク質を発現する細胞に特異的なアデノウイルスベクターおよびその使用の方法 Ceased JP2002516568A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US3959797P 1997-03-03 1997-03-03
US60/039,597 1997-03-03
US09/033,428 1998-03-02
US09/033,428 US6254862B1 (en) 1997-03-03 1998-03-02 Adenovirus vectors specific for cells expressing alpha-fetoprotein and methods of use thereof
PCT/US1998/004084 WO1998039465A2 (en) 1997-03-03 1998-03-03 Adenovirus vectors specific for cells expressing alpha-fetoprotein and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2002516568A JP2002516568A (ja) 2002-06-04
JP2002516568A5 true JP2002516568A5 (enExample) 2005-11-10

Family

ID=21906330

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53867698A Ceased JP2002516568A (ja) 1997-03-03 1998-03-03 α−フェトタンパク質を発現する細胞に特異的なアデノウイルスベクターおよびその使用の方法

Country Status (10)

Country Link
US (2) US6254862B1 (enExample)
EP (1) EP0972063B1 (enExample)
JP (1) JP2002516568A (enExample)
KR (1) KR20000075924A (enExample)
CN (1) CN100390292C (enExample)
AT (1) ATE385256T1 (enExample)
AU (1) AU745560B2 (enExample)
CA (1) CA2282706C (enExample)
DE (1) DE69839071T2 (enExample)
WO (1) WO1998039465A2 (enExample)

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US7011976B1 (en) * 1997-03-03 2006-03-14 Calydon, Inc. Adenovirus vectors specific for cells expressing alpha-fetoprotein and methods of use thereof
US6254862B1 (en) * 1997-03-03 2001-07-03 Calydon, Inc. Adenovirus vectors specific for cells expressing alpha-fetoprotein and methods of use thereof
US20020068049A1 (en) * 1998-09-10 2002-06-06 Henderson Daniel R. Tissue specific adenoviral vectors
US7001764B2 (en) * 1995-06-27 2006-02-21 Cell Genesys, Inc. Compositions comprising tissue specific adenoviral vectors
US20060165658A1 (en) * 1997-03-03 2006-07-27 Little Andrew S Adenovirus vectors specific for cells expressing alpha-fetoprotein and methods of use thereof
WO1999006576A1 (en) * 1997-08-04 1999-02-11 Calydon, Inc. A human glandular kallikrein enhancer, vectors comprising the enhancer and methods of use thereof
US6900049B2 (en) * 1998-09-10 2005-05-31 Cell Genesys, Inc. Adenovirus vectors containing cell status-specific response elements and methods of use thereof
JP2002530085A (ja) * 1998-11-18 2002-09-17 カンジ，インコーポレイテッド 後期導入遺伝子の発現を有するウイルスベクター
US20060024273A1 (en) * 1998-12-30 2006-02-02 Henderson Daniel R Target cell-specific adenoviral vectors containing E3 and methods of use thereof
US6495130B1 (en) * 1998-12-30 2002-12-17 Calydon, Inc. Target cell-specific adenoviral vectors containing E3 and methods of use thereof
US7589069B1 (en) * 1999-07-12 2009-09-15 Saint Louis University Replication-competent anti-cancer vectors
US6627190B2 (en) 1999-07-12 2003-09-30 Saint Louis University Recombinant adenovirus vectors that are replication-competent in tert-expressing cells
WO2001023001A2 (en) 1999-09-29 2001-04-05 The Trustees Of The University Of Pennsylvania Rapid peg-modification
IL151818A0 (en) * 2000-03-21 2003-04-10 Univ Virginia Osteocalcin promoter directed anenovirus replication for therapy
US6692736B2 (en) 2000-03-24 2004-02-17 Cell Genesys, Inc. Cell-specific adenovirus vectors comprising an internal ribosome entry site
WO2001072994A2 (en) 2000-03-24 2001-10-04 Cell Genesys, Inc Human urothelial cell specific uroplakin transcriptional regulatory sequences, vectors comprising the same, and methods of use thereof
US6911200B2 (en) 2000-03-24 2005-06-28 Cell Genesys, Inc. Methods of treating neoplasia with combination of target-cell specific adenovirus, chemotherapy and radiation
US7048920B2 (en) 2000-03-24 2006-05-23 Cell Genesys, Inc. Recombinant oncolytic adenovirus for human melanoma
US6673614B2 (en) 2000-06-27 2004-01-06 Cell Genesys, Inc. Rapid methods and kits for detection and semi-quantitation of anti-adenovirus antibody
US8071740B2 (en) 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
AU2003222427B8 (en) 2000-11-17 2010-04-29 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
EP1377672A2 (en) * 2001-02-23 2004-01-07 Novartis AG Vector constructs
CN100506284C (zh) 2001-10-19 2009-07-01 脉管生物生长有限公司 多核苷酸构建体、药物组合物以及靶向的下调血管生成和抗癌的治疗方法
US20030086903A1 (en) * 2001-11-02 2003-05-08 Genvec, Inc. Therapeutic regimen for treating cancer
CA2478616C (en) * 2002-03-26 2012-05-29 Oncolytics Biotech Inc. Use of adenoviruses mutated in the va genes for cancer treatment
US7364727B2 (en) * 2002-07-22 2008-04-29 Cell Genesys, Inc. Metastatic colon cancer specific promoter and uses thereof
RU2393221C2 (ru) * 2002-10-15 2010-06-27 Пер Сонне ХОЛЬМ Аденовирус с обращенной генной экспрессией и его применение
US20050136035A1 (en) * 2003-06-03 2005-06-23 Derek Ko Cell specific replication-competent viral vectors comprising a self processing peptide cleavage site
WO2005017149A1 (en) * 2003-06-03 2005-02-24 Cell Genesys, Inc. Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site
US20050186178A1 (en) * 2003-08-28 2005-08-25 Ennist David L. Oncolytic adenoviral vectors encoding GM-CSF
CN100420742C (zh) * 2003-09-29 2008-09-24 中国人民解放军军事医学科学院基础医学研究所 一种肝癌靶向性溶瘤腺病毒，其制备方法及用途
US7482156B2 (en) 2003-10-15 2009-01-27 Cell Genesys, Inc. Hepatocellular carcinoma specific promoter and uses thereof
EP1687032B1 (en) * 2003-11-14 2010-02-24 Genvec, Inc. Pharmaceutical composition for treating unresectable, locally advanced pancreatic cancer (lapc).
US7473418B2 (en) 2004-03-25 2009-01-06 Cell Genesys, Inc. Pan cancer oncolytic vectors and methods of use thereof
ES2292271B1 (es) * 2004-05-20 2009-02-16 Proyecto De Biomedicina Cima, S.L. Un vector hibrido adenovirus-alfavirus para la administracion eficaz y expresion de genes terapeuticos en celulas tumorales.
TWI293307B (en) 2004-09-30 2008-02-11 Ind Tech Res Inst A liver-specific chimeric regulatory sequence and use thereof
DE102005055128B4 (de) * 2005-11-15 2015-04-02 Universität Rostock Viraler Vektor, dessen Verwendung zur Therapie von Leberzellkarzinomen und pharmazeutische Mittel umfassend den Vektor
EP1900749A1 (en) * 2006-09-12 2008-03-19 Institut National De La Sante Et De La Recherche Medicale (Inserm) Nucleic acids for expressing a polynucleotide of interest in mammalian cancer cells
WO2008060357A2 (en) * 2006-09-29 2008-05-22 Canji, Inc. Methods of polypeptide production
CN102268454B (zh) * 2007-04-23 2013-07-24 深圳益世康宁生物科技有限公司 一种psma重组腺相关病毒载体及其构建方法与应用
US8968210B2 (en) 2008-10-01 2015-03-03 Covidien LLP Device for needle biopsy with integrated needle protection
US9782565B2 (en) 2008-10-01 2017-10-10 Covidien Lp Endoscopic ultrasound-guided biliary access system
US9186128B2 (en) 2008-10-01 2015-11-17 Covidien Lp Needle biopsy device
US11298113B2 (en) 2008-10-01 2022-04-12 Covidien Lp Device for needle biopsy with integrated needle protection
US9332973B2 (en) 2008-10-01 2016-05-10 Covidien Lp Needle biopsy device with exchangeable needle and integrated needle protection
US9605844B2 (en) * 2009-09-01 2017-03-28 Cree, Inc. Lighting device with heat dissipation elements

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US5328470A (en) 1989-03-31 1994-07-12 The Regents Of The University Of Michigan Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor
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GB8919607D0 (en) 1989-08-30 1989-10-11 Wellcome Found Novel entities for cancer therapy
DK0506945T3 (da) 1990-10-25 1999-04-26 Clague Pitman Hodgson Fremgangsmåde til genoverførsel under anvendelse af retrotransposoner
WO1993019768A1 (en) 1992-04-03 1993-10-14 The Regents Of The University Of California Self-assembling polynucleotide delivery system
US5501662A (en) 1992-05-22 1996-03-26 Genetronics, Inc. Implantable electroporation method and apparatus for drug and gene delivery
DE69431106T2 (de) 1993-05-10 2003-05-08 The Regents Of The University Of Michigan, Ann Arbor Gentransfer zu den pankreatischen epithelzellen
AU687829B2 (en) 1993-06-24 1998-03-05 Advec, Inc. Adenovirus vectors for gene therapy
JP3875990B2 (ja) 1993-10-25 2007-01-31 カンジ，インコーポレイテッド 組換えアデノウイルスベクターおよび使用方法
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US5698443A (en) 1995-06-27 1997-12-16 Calydon, Inc. Tissue specific viral vectors
US5830686A (en) 1994-01-13 1998-11-03 Calydon Tissue-specific enhancer active in prostate
JPH10509880A (ja) 1994-11-28 1998-09-29 ジェネティック セラピー， インコーポレイテッド 組織特異的複製のためのベクター
US5998205A (en) 1994-11-28 1999-12-07 Genetic Therapy, Inc. Vectors for tissue-specific replication
WO1996021036A2 (en) 1994-12-30 1996-07-11 Chiron Viagene, Inc. Nucleic acid condensing agents with reduced immunogenicity
US20030026789A1 (en) 1995-05-03 2003-02-06 Richard J. Gregory Gene therapy using replication competent targeted adenoviral vectors
US6254862B1 (en) * 1997-03-03 2001-07-03 Calydon, Inc. Adenovirus vectors specific for cells expressing alpha-fetoprotein and methods of use thereof
US6403370B1 (en) 1997-02-10 2002-06-11 Genstar Therapeutics Corporation Oncolytic/immunogenic complementary-adenoviral vector system

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